Severe Acute Respiratory News and Research

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Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

A recent study published in the journal Circulation examines the immunological picture in this scenario, looking for clues to the etiology of this rare and potentially serious complication.

5 Jan 2023

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Researchers uncovered a novel mechanism that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses (CoVs) use to exploit host antiviral immune system to facilitate their replication.

5 Jan 2023

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

Researchers investigated whether using patient-preferred scents and a bimodal method of visual-olfactory training is more effective than unimodal olfactory training using scents assigned by physicians in treating patients experiencing anosmia after COVID-19.

5 Jan 2023

What was the effect of the COVID-19 pandemic on the mental well-being of university students?

Researchers evaluated changes in the mental health status of university-attending students in France 15.0 months post-commencement of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

5 Jan 2023

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Researchers investigated the reactogenicity of the COVID-19 vaccine in pediatric patients with MIS-C.

5 Jan 2023

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Researchers conducted a multicenter, cross-sectional seroprevalence study in emergency departments of five hospitals in North Rhine-Westphalia, Germany, between August and September 2022. They assessed point seroprevalence and neutralization activity against Wu01, BA.4/5, and BQ.1.1.

5 Jan 2023

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

Researchers presented a microbody recombinant decoy protein with high affinity to angiotensin-converting enzyme 2 (ACE2) as an option for coronavirus disease 2019 (COVID-19) treatment.

5 Jan 2023

How effective is the bivalent mRNA SARS-CoV-2 vaccine in preventing COVID-19 hospitalizations and deaths?

Researchers examined the effectiveness of the bivalent mRNA vaccine against severe outcomes of COVID-19.

5 Jan 2023

COVID booster shots cut Omicron transmission in closed environments

In a recent paper published in the journal Nature Medicine, researchers in the United States investigated the infectiousness of incarcerated individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infections in prisons, high-risk settings where transmission is intense.

3 Jan 2023

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to compare the effectiveness of the third dose of BNT162b2 or messenger ribonucleic acid (mRNA)-1273 vaccine among United States (US) veterans.

3 Jan 2023

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Researchers evaluated the seroprevalence and durability of antibodies against SARS-CoV-2 nucleocapsid protein among pregnant individuals and investigated transplacental antibody transfer.

3 Jan 2023

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

Researchers collaborated with community partners to monitor SARS-CoV-2 infections among domestic and free-ranging animals with known susceptibility to the virus and proximity to humans in Ohio, United States.

3 Jan 2023

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Scientists have described the utility of gram-negative bacteria-derived outer membrane vesicles as vaccines and methods to expand their applications.

3 Jan 2023

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

Researchers analyzed the ribonucleic acid (RNA) transcriptome associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV-1-infected human cells.

3 Jan 2023

What is the global state of SARS-CoV-2 seroprevalence in children?

Researchers conducted a systematic review to assess global pediatric SARS-CoV-2 seroprevalence.

3 Jan 2023

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

How can we characterize the burden of post-acute sequelae of COVID-19 in the community?

Researchers characterized the burden of post-acute sequelae of coronavirus disease 2019 (COVID-19) [PASC] in community-dwelling individuals.

3 Jan 2023

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

Researchers longitudinally evaluated humoral immune responses to the second and third doses of COVID-19 mRNA vaccines among individuals with and without prior history of SARS-CoV-2 infections.

3 Jan 2023

What is the impact of COVID-19 on the human genetic architecture?

Researchers recently described the second update on the study of human genetic architecture with respect to the effect of coronavirus disease 2019 (COVID-19).

3 Jan 2023

Why do some people develop persistent lung sequelae after severe COVID-19?

Clinical presentation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from mild self-limiting illness to severe respiratory failure. Many studies have analyzed the early acute phases of coronavirus disease 2019(COVID-19), but few focused on the longer-term sequelae following infection.

2 Jan 2023

Severe Acute Respiratory News and Research

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Does bimodal visual-olfactory training with patient-preferred scents improve olfaction in individuals with COVID-19 postviral olfactory loss?

What was the effect of the COVID-19 pandemic on the mental well-being of university students?

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Seroprevalence study demonstrates vaccination could boost impaired humoral immunity against Omicron BQ.1.1 subvariant

Study shows angiotensin-converting enzyme 2 decoy protein as a promising anti-SARS-CoV-2 agent

How effective is the bivalent mRNA SARS-CoV-2 vaccine in preventing COVID-19 hospitalizations and deaths?

COVID booster shots cut Omicron transmission in closed environments

Study compares effectiveness of Pfizer vs. Moderna booster COVID vaccines after third dose

Longitudinal seroprevalence study among pregnant people indicates waning of immunity from natural SARS-CoV-2 infections

Scientists collaborate to monitor SARS-CoV-2 RNA among domestic and free-ranging animal species

Bacterial outer membrane vesicles: utility as vaccines and novel engineering approaches

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

What is the global state of SARS-CoV-2 seroprevalence in children?

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

How can we characterize the burden of post-acute sequelae of COVID-19 in the community?

Effects of hybrid immunity on humoral immune response following COVID mRNA vaccination in a cohort of essential and frontline workers

What is the impact of COVID-19 on the human genetic architecture?

Why do some people develop persistent lung sequelae after severe COVID-19?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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