Severe Acute Respiratory News and Research

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Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2

Researchers demonstrated that a trivalent vaccine against SARS-CoV-2 improved the breadth of humoral immune responses in mice.

19 Dec 2022

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Researchers reported the waning of antibodies against SARS-CoV-2 in the six months following a booster dose of the mRNA COVID-19 vaccine.

19 Dec 2022

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

Researchers evaluated the immunogenicity and safety of the COVID-19 bivalent mRNA vaccine mRNA-1273.222 and tested the neutralizing ability of the two bivalent vaccines — mRNA-1273.222 and mRNA-1273.214 — against the newly emergent Omicron subvariants.

19 Dec 2022

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

A new study in the journal Vaccines aimed to analyze the long-term kinetics of SARS-CoV-2 specific T cell and humoral responses following primary and booster vaccinations in previously infected individuals.

18 Dec 2022

Excess COVID-19-associated death estimates by World Health Organization

Researchers presented a comprehensive report on the estimated impact of the SARS-CoV-2 pandemic by estimating month-wise excess deaths for the years 2020 and 2021.

16 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Researchers developed a one-dose subunit vaccine for the induction of durable, potent, and broad immunity against SARS-CoV-2.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

Researchers demonstrated the exceptional immune evasion properties of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, BQ and XBB.

16 Dec 2022

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

A recent study reported that in the two years following the initiation of the US COVID-19 vaccination campaign, over 18 million hospitalizations and three million deaths have been prevented, and close to $1.15 trillion have been saved in medical costs.

16 Dec 2022

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

mRNA-FISH for the detection of viral RNA in SARS-CoV-2 infected cells and the determination of the kinetics of early RNA replication

Researchers evaluated the early replication kinetics of SARS-CoV-2.

15 Dec 2022

Protein expression signature distinguishes early from late stage diffuse alveolar damage

Researchers identified a protein expression signature that can distinguish early diffuse alveolar damage (DAD) from late DAD in coronavirus disease 2019 (COVID-19) patients.

15 Dec 2022

Severe Acute Respiratory News and Research

Study demonstrates robust antibody response elicited by trivalent protein subunit vaccine against SARS-CoV-2

Rise and waning of SARS-CoV-2 antibody responses induced by mRNA vaccine booster in a healthcare worker population

Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

Excess COVID-19-associated death estimates by World Health Organization

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

The UK's growing burden of long-COVID

Novel machine learning method detects animal coronaviruses that might infect humans

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

What influence has COVID-19 vaccination had on sperm characteristics?

mRNA-FISH for the detection of viral RNA in SARS-CoV-2 infected cells and the determination of the kinetics of early RNA replication

Protein expression signature distinguishes early from late stage diffuse alveolar damage

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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