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Study sheds new light on cell division fidelity, can impact future regenerative medicine

Researchers discover that a specialized part of the chromosomes, essential for a correct cell division, is smaller and weaker in stem cells, when compared to the ones of differentiated cells.

29 Oct 2020

Genetic analysis with RNA sequencing can increase diagnostic yield, shows study

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

28 Oct 2020

Researchers discover gene that may help the body sense a full urinary bladder

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be responsible for the powerful urge to urinate that we normally feel several times a day. The

19 Oct 2020

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, epidermis and hair follicles.

16 Oct 2020

Novel findings on mole growth could pave way for skin cancer treatments

Moles stop growing when they reach a certain size due to normal interactions between cells, despite having cancer-associated gene mutations, says a new study published today in eLife.

13 Oct 2020

New efficacies of Ganoderma lucidum as anti-inflammatory agent for the skin

Ganoderma lucidum, known as Yeongji mushroom in Korea, is called a modern-day elixir plant and has long been used medicinally in China, Japan and Korea.

7 Oct 2020

First biobank in Australia for chromosome 15 disorders

The first biobank in Australia aiming to improve research and treatments into rare genetic diseases caused by changes to genes on chromosome 15, including Prader-Willi Syndrome and Angelman Syndrome, will be established at the Murdoch Children's Research Institute.

5 Oct 2020

Scientists discover small molecules that may reduce cellular stress

For many, getting older can unfortunately mean an increased risk of illness from cardiovascular disease to cancer.

5 Oct 2020

Planaria flatworm can be used as reliable alternative for testing topical skin products

Tests for skin treatments could be screened using flatworms rather than other animals such as rabbits, according to new research.

1 Oct 2020

Stanford researchers unravel how a common genetic deletion elevates schizophrenia risk

A common genetic deletion boosts the risk for schizophrenia by 30-fold. Generating nerve cells from people with the deletion has showed Stanford researchers why.

28 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

Scientists elucidate cause for Parkinson's disease and identify potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

12 Sep 2020

New research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

14 Aug 2020

Researchers develop skin-friendly, antimicrobial wound dressing

If germs invade a wound, they can trigger a long-lasting infection that may fail to heal or even spread throughout the body, leading to life-threatening blood poisoning (sepsis).

11 Aug 2020

Applying "temporal pressure" to the skin can help deliver more drugs

Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR) have showed that applying "temporal pressure" to the skin of mice can create a new way to deliver drugs.

4 Aug 2020

siRNA-based treatment can reduce psoriasis symptoms

Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide.

23 Jul 2020

Sanford Burnham Prebys receives CIRM award to advance promising drug candidates for COVID-19

Sanford Burnham Prebys Medical Discovery Institute has received an award from the California Institute for Regenerative Medicine to advance promising drug candidates for COVID-19.

21 Jul 2020

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.

21 Jul 2020

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

30 Jun 2020

Study sheds new light on eczema

A new study from researchers at Binghamton University, State University of New York may help to peel back the layers of unhealthy skin -- at least metaphorically speaking -- and get closer to a cure.

24 Jun 2020