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Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

Forbidden fruit: Scientists venture into “embryoid” manufacturing

After working on stem cells for several years, scientists have now announced that they have found a way to synthesize structures that look like very primitive human embryos. While some hailed the discovery, others questioned the ethical basis of manufacturing synthetic humans.

12 Sep 2019

Too much vitamin D may reduce bone density, say scientists

Excessive supplementation with vitamin D can cause bone loss and bone weakening, according to a new study.

6 Sep 2019

Neurobiological pathophysiology of schizophrenia differs based on gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study.

4 Sep 2019

Study reshapes the understanding of telomerase's function in normal cells

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase.

3 Sep 2019

Lab-grown brain organoids and the brains of preemie babies generate similar electrical impulses

Brain organoids — also called mini-brains — are 3D cellular models that represent aspects of the human brain in the laboratory. Brain organoids help researchers track human development, unravel the molecular events that lead to disease and test new treatments.

30 Aug 2019

Psychopathy associated with robust alterations in expression of genes, study shows

The expression of many genes that have previously been associated with autism is abnormal also in violent psychopathy, a new study shows.

30 Aug 2019

“Mini Brains” in the lab show electrical activity similar to a preemie’s brain

Researchers have developed successfully mini brains in the labs which are essentially a cluster of brain cells perfused in fluids. These brain tissues are now showing electrical activity akin to real brain, explain the researchers and this is a path-breaking development in brain research.

29 Aug 2019

New study reveals mechanism of ultraviolet-induced skin breakdown

The sunscreen industry has been plugging the use of various sun-protective creams for decades, ever since researchers found that certain skin cancers, including malignant melanoma, were due to sunlight-induced skin damage.

22 Aug 2019

MSD collaborates with Francis Crick to find causes of motor neurone disease

Scientists at global biopharmaceutical company MSD and the Francis Crick Institute have started a unique new collaboration to understand the causes of Motor Neurone Disease and identify potential targets for future treatments, co-funded by MSD and the UK Medical Research Council.

21 Aug 2019

Study identifies key epigenetic regulator that controls skin cell turnover

The outer layer of the skin completely replaces itself every two to four weeks, but when this process is blocked, cancer can grow.

21 Aug 2019

Mini kidneys grown in the lab could be used to better understand kidney diseases

An international team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients.

20 Aug 2019

Pitt researchers first to grow genetically modified miniature human livers in the lab

Researchers at the University of Pittsburgh School of Medicine are the first to grow genetically modified miniature human livers in the laboratory, to emulate human liver disease progression and test therapeutics.

7 Aug 2019

Sheffield academic receives funding to protect brain cells affected by Parkinson's

A Sheffield academic has been awarded £100,000 of funding by the Virtual Biotech Programme - the drug development arm of charity Parkinson's UK - to develop a new treatment that could protect brain cells affected by Parkinson's disease, potentially slowing, or stopping its progression for the first time.

6 Aug 2019

Tel Aviv researchers develop a nano-vaccine for the most aggressive skin cancer

Researchers at Tel Aviv University have developed a novel nano-vaccine for melanoma, the most aggressive type of skin cancer.

5 Aug 2019

First-of-its-kind study in space station seeks to find causes of major diseases

High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking for what triggers these diseases by studying how nerve and immune brain cells interact.

1 Aug 2019

Skin cancer risk falls with higher dietary vitamin A intake

A new study from Brown University shows that the dietary intake of vitamin A from plant sources is associated with a lower risk of a common type of skin cancer called squamous cell carcinoma. This is the second most common carcinoma of the skin in fair-skinned people.

1 Aug 2019