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New insights into the molecular basis of schizophrenia during early brain development

Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated.

24 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

Lab-grown skin organoids help scientists understand monkeypox infection

Skin organoids offer a powerful platform for drug discovery in the ongoing fight against the virus formerly known as monkeypox.

16 Oct 2023

Save the environment and protect your skin while doing it – the 'cherry on top'

Researchers discover a sustainable way to repurpose tart cherry waste, harnessing its bioactive compounds for skin care applications. The study reveals that these extracts significantly protect human skin cells from oxidative stress, offering an eco-friendly solution to both food waste and skin health.

16 Oct 2023

Skin under pressure: tension affects skin's reaction to pollution

Researchers ratified previous findings that ozone (O3) exposure (an air pollutant) alters the antimicrobial peptide expression in the skin with and without tension.

27 Sep 2023

Gene-silencer study could pave the way for novel cancer therapeutics

Deep inside our cells-;each one complete with an identical set of genes-;a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, versus brain or muscle or skin cells.

26 Sep 2023

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

University of Arkansas receives $3.1 million NIH award to study pediatric mitochondrial disorders

The Eunice Kennedy Shriver National Institute of Child Health and Human Development awarded $3.1 million to the University of Arkansas to study a spectrum of pediatric mitochondrial disorders caused by mutations in the mitochondria.

20 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Global team of experts outlines roadmap for human skin cell atlas

As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking.

21 Aug 2023

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions.

10 Aug 2023

GABA transfer between skin cells promotes melanoma initiation

The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in Cancer Discovery, a journal of the American Association for Cancer Research.

9 Aug 2023

Researchers discover cause of cholesteatomas

Chronic inflammation of the middle ear can cause several problems and complications that can affect a person's hearing and balance.

3 Aug 2023

Study uncovers the science behind the body's tanning process after leaving the beach

Beachgoers are familiar with the experience of spending hours in the sun, going home, and noticing only hours later that their skin has changed color.

3 Aug 2023

Study provides valuable insights into the UV susceptibility of SARS-CoV-2 omicron variants

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens.

27 Jul 2023

STEMCELL Technologies celebrates 30 years with unprecedented annual growth

STEMCELL Technologies, Canada’s largest biotechnology company, is marking its 30th year of accelerating research into cancer and other diseases by celebrating its culture of collaboration, curiosity, and discovery.

26 Jul 2023

Vitamin D levels could play an important role in psoriasis severity

More than eight million people in the U.S. experience psoriasis, a condition in which skin cells build up and form itchy dry patches.

25 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

Study explores how ultraviolet radiation can alter the microstructure of human skin

Received wisdom says that staying out in the sun too long can make your skin tougher over time. Think about the "leathery" complexions of farmers, road crews and others who work long hours outdoors, or someone who spends too much time in tanning booths, or too much time on the beach during the summer.

19 Jul 2023