Small Intestine News and Research

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Limited gut inflammation in COVID-19

A new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in September 2020 shows that gut infection with this virus produces primarily mucosal immunity but also a limited inflammatory response.

8 Sep 2020

Host tissue T cells play a previously unappreciated role in acute graft-versus-host disease

Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor's healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer.

28 Aug 2020

Gastric bypass surgery is the most effective therapy to treat type 2 diabetes

Gastric bypass surgery is the most effective therapy to treat or reverse type 2 diabetes in severely obese patients.

20 Aug 2020

Membrane nanoparticles acts as a bait to trap SARS-CoV-2

In an exciting new bioRxiv preprint research paper, Chinese researchers describe the development of membrane nanoparticles from ACE2-rich cells with a potent capacity to block the adherence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2020

Diet, not gastric bypass surgery, accounts for improved health

In many studies, bariatric surgery has been highlighted as an almost magical method for weight loss and reversing type 2 diabetes.

13 Aug 2020

Researchers develop new tool that acts like colonoscopy

Your gut bacteria could say a lot about you, such as why you're diabetic or how you respond to certain drugs. But scientists can see only so much of the gastrointestinal tract to study the role of gut bacteria in your health.

13 Aug 2020

FDA issues final rule to establish compliance requirements for fermented and hydrolyzed foods

Today, the U.S. Food and Drug Administration issued a final rule to establish compliance requirements for fermented and hydrolyzed foods, or foods that contain fermented or hydrolyzed ingredients, and that bear the "gluten-free" claim. The rule pertains to foods such as soy sauce, yogurt, sauerkraut, pickles, cheese and green olives.

12 Aug 2020

Scientist explains why COVID-19 targets only some organs while others are spared

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the enzyme angiotensin-converting enzyme 2 (ACE2) to enter and infect human cells. It causes COVID-19 and can lead to a multitude of complications, including multi-organ impairment, partially due to the abundant expression of ACE2 in all human tissues.

11 Aug 2020

Antioxidant-rich foods may increase risk for bowel cancers, study finds

It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to "attract" cancer?

29 Jul 2020

Finding the right treatment for people with IBD may soon become easier

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease, might soon be getting easier.

27 Jul 2020

Study may lead to more effective treatments for chronic intestinal inflammation

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease (IBD), might soon be getting easier. World IBD Day happens on 19 May each year, with the goal to raise awareness about the disease and urge action.

23 Jul 2020

Mouse model of fatal COVID-19 developed for vaccine and drug testing

Now, a new study published on the preprint server bioRxiv in July 2020 presents an engineered transgenic mouse that reproduces the functional and clinical characteristics of severe human SARS-CoV-2 infection.

21 Jul 2020

Researchers to create AI-based pill to precisely diagnose gastrointestinal cancers

A team led by University of Saskatchewan (USask) researcher Khan Wahid has been awarded $250,000 from the federal New Frontiers in Research Fund to create a new pill-sized capsule that uses artificial intelligence (AI)-enabled sensing to diagnose gastrointestinal cancers and bleeding earlier and more precisely than is currently possible.

9 Jul 2020

New radiopharmaceutical shows excellent imaging performance in tumor detection

For neuroendocrine cancer patients with liver metastases, a new radiopharmaceutical, 68Ga-DOTA-JR11, has shown excellent imaging performance in tumor detection, staging, and restaging, providing important information to guide treatment.

26 Jun 2020

Irritable bowel disease heightens the risk of dementia

Scientists have long explored the link between the gut and the brain. Now, a new study shows that older adults with chronic inflammation of the digestive tract may develop dementia more than seven years earlier than those who do not have the condition.

26 Jun 2020

Prior infection provides protection against SARS-CoV-2 virus in hamsters

In an animal model for COVID-19 that shares important features of human disease, scientists at the University of Wisconsin–Madison, the University of Tokyo and the Icahn School of Medicine at Mount Sinai show that prior infection with the SARS-CoV-2 virus provides protection against reinfection, and treatment with convalescent serum limits virus replication in their lungs.

22 Jun 2020

Parasitic worms could offer new treatment hope for MS patients

Parasitic worms could offer a new treatment hope for patients suffering from the autoimmune disease multiple sclerosis, according to experts from the University of Nottingham.

18 Jun 2020

Antibiotic X-206 effective against SARS-CoV-2 in vitro

The current study published on the preprint server bioRxiv aims to understand how these compounds affect SARS-CoV-2 in vitro. The researchers from Aarhus University in Denmark examined 11 natural PEIs, with a single synthetic analog, screening them for inhibitory activity against the CPE of SARS-CoV-2 infecting cultured cells with overexpression of TMPRSS2, a serine protease that is instrumental in cleaving the spike protein of the virus.

16 Jun 2020

Study finds drivers of healthy gut maintenance

Researchers at the Francis Crick Institute have found two genes that regulate the differentiation of stem cells in the small intestine, offering valuable insight into how the body develops and maintains a healthy gut.

15 Jun 2020

COVID-19 may trigger the onset of diabetes in healthy people

Emerging evidence suggests that COVID-19 may actually trigger the onset of diabetes in healthy people and also cause severe complications of pre-existing diabetes.

12 Jun 2020