Smallpox News and Research

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Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.

Animals diseases jumping to humans faster than ever before

According to scientists in the U.S. and Scotland, 75% of the 38 species of harmful organisms and viruses identified in the past 25 years are believed to have "jumped" from animals to humans.

21 Feb 2006

Protein finding could lead to new topical treatment for inflammatory diseases

A protein that undesirably shields a skin poxvirus from the immune system may become the key ingredient in a new topical treatment for inflammatory diseases, say medical researchers at the University of Illinois at Urbana-Champaign.

11 Jan 2006

New technique points to safer, more efficient vaccination

Researchers have demonstrated a technique that has the potential to reduce the toxicity of vaccines and to make smaller doses more effective, according to a study published in PLoS Pathogens.

6 Jan 2006

UCLA examines disease-versus-disease interactions

The knowledge that one disease may prevent the onset of another is not new. For example, the discovery that cowpox vaccines can prevent smallpox dates back to 1798.

5 Jan 2006

Technique to reduce the toxicity of vaccines demonstrated

Researchers have demonstrated a technique that has the potential to reduce the toxicity of vaccines and to make smaller doses more effective, according to a study published in PLoS Pathogens.

30 Dec 2005

Local health officials don't rate U.S. government bird flu plans

Health officials in the U.S. have predicted, in the event of a bird flu pandemic, businesses and government can expect 40 percent of their employees to be absent during it's peak.

6 Dec 2005

Video game prepares health workers for disasters

A video game that simulates biological, chemical, radiological and natural disasters in a major metropolitan area, developed by a team from the University of Illinois at Chicago, will be used to prepare public health workers and emergency responders for real life emergencies.

27 Oct 2005

Online education program improved physicians' knowledge about the diagnosis and management of diseases caused by bioterrorism

In the event of a biologic attack, physicians will be first responders and represent the front line of defense, but little is known about the ability of physicians to appropriately diagnose and treat patients infected with bioterrorism agents, according to background information in the article.

27 Sep 2005

Antibody in humans that quickly fights the smallpox virus

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) have made a major advancement toward protecting society against a smallpox outbreak by identifying an antibody in humans that quickly fights the smallpox virus.

26 Sep 2005

Healthcare workers may be unable or unwilling to report to work during certain disasters

In a first study of its kind, researchers at the Mailman School of Public Health assessed the ability and willingness of healthcare workers to report to work in the event of disasters involving weapons of mass destruction or virulent infectious disease outbreaks.

12 Sep 2005

Unexpected link between the viruses that cause feline and human AIDS

A University of Florida researcher has discovered an unexpected link between the viruses that cause feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS virus appear to be at least as well-protected against the feline version of the disease as those immunized with the vaccine currently used by veterinarians.

10 Sep 2005

Funding the "war on terror" could cost the lives of millions of Americans

Professor Erica Frank argues that the US government's decision to shift funds away from basic public health services towards preventing terrorism has cut funding for common diseases and for disaster relief, resulting in enormous numbers of unnecessary deaths.

10 Sep 2005

HHS orders 20 million doses of smallpox vaccine from Bavarian Nordic

Bavarian Nordic has announced that it has received the requirements from the U.S. government's Department of Health and Services (HHS), for the purchase of 20 million doses of an MVA-based smallpox vaccine.

16 Aug 2005

Researchers develop new diagnostic methods to better detect future monkeypox or smallpox outbreaks

The research also sheds new light on the 2003 monkeypox outbreak in the Midwest - monkeypox is closely related to smallpox. This new information suggests that the 2003 outbreak was larger than the 72 cases reported by the Centers for Disease Control and Prevention (CDC).

9 Aug 2005

Models may risk making overly optimistic predictions about the levels of public health interventions needed to bring a disease under control

Mathematical models have become invaluable decision-making tools for public health officials. As demonstrated during the United Kingdom's foot-and-mouth epidemic of 2001, models can be useful in two ways: they can reveal the underlying characteristics of an infection and they can allow the comparison of alternative control measures.

26 Jul 2005