Spectrometer News and Research

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Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry

Understanding the chemical composition and organization of cell membranes - what components reside next to each other, how many of each there are and how they respond to their environment - may reveal the secret lives of cells in both health and disease.

9 Oct 2006

Dual-mode nanoscale imaging yields new details of cellular events

To create drugs capable of targeting malignancies, scientists must first decode exactly how a cell or a group of cells communicates with other cells and reacts to a broad spectrum of complex biomolecules surrounding it.

21 Aug 2006

FDA develops cost-effective way to identify bioterror agents used in hoax incidents

Researchers at the Food and Drug Administration (FDA) National Center for Toxicological Research (NCTR) are developing a quick, cost-effective way to screen for and identify bioterror agents and other substances used in hoax incidents.

3 Aug 2006

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes are caused by enzyme deficiencies and typically have crippling, even fatal, consequences starting at very early ages.

13 Apr 2006

Link between lead and osteoporosis strengthens

Bolstered by recent laboratory findings, researchers at the University of Rochester Medical Center are embarking on a National Institutes of Health-funded clinical study to better understand the deceptive role environmental lead exposure plays in bone maturation and loss.

4 Apr 2006

New technology - desorption electrospray ionization detects the boundaries of cancerous tumors

Researchers at Purdue University have shown how a new ultra-fast chemical-analysis tool has numerous promising uses for detecting everything from cancer in the liver to explosives residues on luggage and "biomarkers" in urine that provide an early warning for diseases.

21 Mar 2006

New system for analyzing how drugs bind to proteins

Researchers at Florida State University's National High Magnetic Field Laboratory and Scripps Florida have developed and evaluated a robust new system for analyzing how drugs bind to proteins. This groundbreaking work could speed the delivery of potential new drugs and improve existing ones.

19 Feb 2006

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions.

7 Feb 2006

Chemical warfare agent detection technology used to treat lung disease

A new technique based on the same technology used to detect chemical warfare agents and explosives is being employed by scientists at The University of Manchester to treat hospital patients with lung disease.

From The University of Manchester 23 Jan 2006

Robotic microbial protein analysis

Microorganisms have potential as living factories for manufacturing drugs and biochemical products. Rapid mass screening methods are needed to identify new species. A new robotic system also provides useful data for genetic engineering.

15 Dec 2005

Possible toxic damage from inhaled nanoparticles

A physicist and a medical researcher at the University of Leicester have received a grant of £100,000 from the Engineering and Physical Sciences Research Council to look at possible toxic damage from inhaled nanoparticles used for a range of everyday purposes.

27 Oct 2005

Fluorescence spectroscopy able to detect the presence of inflammatory cells that are associated with critical atherosclerotic plaques

Because atherosclerotic plaque typically builds up without symptoms and leads to more than 1 million deaths in America each year, the search is on to develop early detection devices that will enable physicians to offer treatment before the disease progresses to advanced stages.

13 Aug 2005

New device has the potential to significantly reduce sequencing of the human genome

The sequencing of the human genome was only the beginning of a much more complex task – deciphering the secrets of cellular chemistry and the mechanisms of disease. While the genome serves as a blueprint to understanding the body, proteins represent the materials that carry out these plans.

8 Jun 2005

Fluorescence device to diagnose atherosclerosis and tumors

In a presentation at the Conference on Lasers and Electro-Optics (CLEO), researchers from Cedars-Sinai Medical Center's Biophotonics Research and Technology Development Laboratory described recent progress on a device that stimulates, collects and measures light emissions from body tissues to diagnose critical atherosclerotic plaques (vulnerable plaques) and aggressive brain tumors.

29 May 2005

Ultrafast laser detection of cancer cells also may improve understanding of stem cells

To investigate tumors, pathologists currently rely on labor-intensive microscopic examination, using century-old cell-staining methods that can take days to complete and may give false readings.

23 Mar 2005

Novel method of testing exhaled breath to detect infection

Researchers from Johns Hopkins University are developing a novel method of testing exhaled breath to detect infection rapidly after potential exposure to a biological warfare agent. They report their findings today at the 2005 ASM Biodefense Research Meeting.

22 Mar 2005

Spectrometer News and Research

Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry

Dual-mode nanoscale imaging yields new details of cellular events

FDA develops cost-effective way to identify bioterror agents used in hoax incidents

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Link between lead and osteoporosis strengthens

New technology - desorption electrospray ionization detects the boundaries of cancerous tumors

New system for analyzing how drugs bind to proteins

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

Chemical warfare agent detection technology used to treat lung disease

Robotic microbial protein analysis

Possible toxic damage from inhaled nanoparticles

Fluorescence spectroscopy able to detect the presence of inflammatory cells that are associated with critical atherosclerotic plaques

New device has the potential to significantly reduce sequencing of the human genome

Fluorescence device to diagnose atherosclerosis and tumors

Ultrafast laser detection of cancer cells also may improve understanding of stem cells

Novel method of testing exhaled breath to detect infection

Claims about the experimental protein-based assay are not biologically plausible

Researchers shed new light on the development of cancers, particularly breast and prostate cancer

Scientists and clinicians are pioneering the diagnosis and treatment of children's brain tumours

New optical technology will help date a persons bruises

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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