Splicing News and Research

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New SARS-CoV-2 mechanism of host gene suppression

New SARS-CoV-2 mechanism of host gene suppression

Study uncovers a subset of human short introns spliced out by a distinct mechanism

Study uncovers a subset of human short introns spliced out by a distinct mechanism

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Next-generation CRISPR tools and therapies improved by modified RNA guides

Next-generation CRISPR tools and therapies improved by modified RNA guides

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Researchers gain new insights into the pathology of Usher syndrome

Researchers gain new insights into the pathology of Usher syndrome

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

New components for oligonucleotide drugs show safety, efficacy in treating spinal muscular atrophy

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Leducq Foundation  provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Could CRISPR be used as a SARS-CoV-2 antiviral?

Could CRISPR be used as a SARS-CoV-2 antiviral?

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

RNA secondary structures can contribute strongly to gene regulation, research shows

RNA secondary structures can contribute strongly to gene regulation, research shows

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Study sheds light on how tau aggregates promote Alzheimer’s disease

Study sheds light on how tau aggregates promote Alzheimer’s disease

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Cell receptor neuropilin-1 offers a promising anti-tumor strategy

Researchers examine circRNAs encoded by MERS-CoV, SARS-CoV-1 and SARS-CoV-2

Researchers examine circRNAs encoded by MERS-CoV, SARS-CoV-1 and SARS-CoV-2

Researchers examine SARS-CoV-2 RNA interactome

Researchers examine SARS-CoV-2 RNA interactome

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