Squamous Cell Carcinoma News and Research

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Squamous Cell Carcinoma is cancer that begins in squamous cells, which are thin, flat cells that look like fish scales. Squamous cells are found in the tissue that forms the surface of the skin, the lining of the hollow organs of the body, and the passages of the respiratory and digestive tracts. Also called epidermoid carcinoma.

Change in genome of Caucasians could explain higher rates of esophageal cancer

A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

21 Dec 2018

New study shows added benefit of ingenol mebutate for patients with actinic keratosis

Already in 2013, the German Institute for Quality and Efficiency in Health Care examined in an early benefit assessment whether ingenol mebutate offers greater benefit than the appropriate comparator therapy for patients with actinic keratosis.

7 Dec 2018

New discovery offers parameter for predicting progression of oral cancer

Researchers in Brazil have identified a correlation between oral cancer progression and the abundance of certain proteins present in tumor tissue and saliva.

5 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Skin cancer rates 350% more than previous estimates suggested, new UK database reveals

Data from the newly established UK skin cancer database, the largest database of its kind in the world, has revealed that there are over 45,000 cutaneous squamous cell carcinomas (cSCC) every year in England, 350 per cent more than previous estimates suggested.

29 Nov 2018

Lower levels of protein make squamous carcinoma cells more invasive

Loss of a protein called TRIM29 promotes cancer cell invasion in a common type of skin cancer, suggesting a novel diagnostic marker and a possible therapeutic target.

21 Nov 2018

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Over 90% of malign tumors in the head and neck are originated from carcinomas of squamous cells that appear in superficial areas of the oral cavity. Their detection with salivary biomarkers can contribute to their early treatment, before they transform into tumors.

14 Nov 2018

Breakthrough research could lead to a new wave of cancer-fighting antibodies

Scientists at the University of Southampton have developed a new antibody that could hold the key to unlocking cancer's defense against the body's immune system.

13 Nov 2018

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Two recent studies find advances in radiation therapy are helping to prolong or improve the lives of people with anal cancer, including those whose cancer has advanced to stage IV.

8 Nov 2018

Head and neck cancer survivors more likely to commit suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers.

25 Oct 2018

New liquid biopsy test confirms remission in patients with HPV-associated oropharyngeal cancer

A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous cell carcinoma are free from cancer following radiation therapy.

23 Oct 2018

Novel blood test shows promise for monitoring HPV-linked head and neck cancer after treatment

A new blood test developed by University of North Carolina Lineberger Comprehensive Cancer Center researchers shows promise for tracking HPV-linked head and neck cancer patients to ensure they remain cancer-free after treatment.

23 Oct 2018

Immunotherapy with pembrolizumab extends survival in metastatic or recurrent head and neck cancer

Immunotherapy with pembrolizumab improves survival in patients with head and neck cancer that has recurred or metastasized, according to late-breaking results from the KEYNOTE-048 study reported at the ESMO 2018 Congress in Munich.

22 Oct 2018

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Bristol-Myers Squibb Company today announced four-year data from the Phase 3 CheckMate -067 clinical trial - the longest follow-up to date - which continues to demonstrate durable, long-term survival benefits with the first-line combination of Opdivo (nivolumab) and Yervoy (ipilimumab), versus Yervoy alone, in patients with advanced melanoma.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

Researchers at La Jolla Institute for Immunology and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute's Cancer Moonshot initiative.

19 Oct 2018

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Squamous cell carcinomas are aggressive malignancies arising from squamous epithelium of various organs, such as esophagus, head and neck, lung and skin. Previous studies demonstrated that two master transcription factors, TP63 and SOX2, effect genomic activation in SCCs.

15 Oct 2018

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

The U.S. Food and Drug Administration today approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma or locally advanced CSCC who are not candidates for curative surgery or curative radiation.

28 Sep 2018

Squamous Cell Carcinoma News and Research

Further Reading

Change in genome of Caucasians could explain higher rates of esophageal cancer

New study shows added benefit of ingenol mebutate for patients with actinic keratosis

New discovery offers parameter for predicting progression of oral cancer

Researcher discovers key differences in protein production between healthy cells and tumors

International study increases group of lung cancer patients who may benefit from immunotherapy

Skin cancer rates 350% more than previous estimates suggested, new UK database reveals

Lower levels of protein make squamous carcinoma cells more invasive

Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer

Breakthrough research could lead to a new wave of cancer-fighting antibodies

Advances in radiation treatment help prolong, improve lives of people with anal cancer

Head and neck cancer survivors more likely to commit suicide

New liquid biopsy test confirms remission in patients with HPV-associated oropharyngeal cancer

Novel blood test shows promise for monitoring HPV-linked head and neck cancer after treatment

Immunotherapy with pembrolizumab extends survival in metastatic or recurrent head and neck cancer

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

FDA approves first intravenous treatment for metastatic cutaneous squamous cell carcinoma

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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