Squamous Cell Carcinoma News and Research

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Squamous Cell Carcinoma is cancer that begins in squamous cells, which are thin, flat cells that look like fish scales. Squamous cells are found in the tissue that forms the surface of the skin, the lining of the hollow organs of the body, and the passages of the respiratory and digestive tracts. Also called epidermoid carcinoma.

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year.

30 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Researchers find way to inactivate cancer protein with the help of another protein

Squamous cell carcinoma is a very unusual type of cancer. They occur in many tissues – for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin.

10 Mar 2020

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

A new phase II trial finds that a combination of radiation therapy and immunotherapy led to encouraging survival outcomes and acceptable toxicity for patients with locally advanced head and neck squamous cell carcinoma

27 Feb 2020

Drug used for breast, renal cancers may provide survival benefit for patients with head and neck cancers

A targeted therapy drug used for breast and kidney cancers may also extend progression-free survival for patients with advanced head and neck cancer who are at high risk for recurrence after standard treatment.

27 Feb 2020

Researchers map the cellular diversity of entire salivary gland tumors

What goes on inside and between individual cells during the very earliest stages of tumor development? Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells.

20 Feb 2020

Cancer risk in psoriatic patients

A new study published in February 2020 in the journal JAMA Dermatology reports that there is a 21% increased risk of cancer in patients with psoriasis, but not with psoriatic arthritis alone.

19 Feb 2020

IU researcher identifies new genomic regions that increase skin cancer risk

An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer.

18 Feb 2020

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progression, researchers from The University of Texas MD Anderson Cancer Center report in the journal Nature today.

13 Feb 2020

Racial, socioeconomic disparities found among patients with HPV-positive oropharyngeal cancer

Survival outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck have made significant gains in recent years, but new research in the February 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds some groups are being left behind.

6 Feb 2020

UArizona receives $6.9 million grant to make advances in skin cancer prevention and treatment

Skin cancer is the most common malignancy worldwide, and one in three new cancers diagnosed is a form of skin cancer, according to the Skin Cancer Foundation. This amounts to about 5 million non-melanoma skin cancers in the United States each year.

6 Feb 2020

RNA affecting skin cancer progression discovered

Researchers at the University of Turku, Turku University Central Hospital, and Western Cancer Center have discovered a new RNA molecule, PRECSIT, which regulates the growth and invasion of squamous cell carcinoma of the skin.

4 Feb 2020

Study looks into the virome of early stage, p16-positive OPSCC and neck metastasis

In this prospective study, a pan-pathogen microarray was used to determine the virome of early stage, p16-positive OPSCC and neck metastasis treated with transoral robotic surgery and neck dissection.

27 Jan 2020

Researchers develop new isolated limb infusion method for melanoma treatment

Worldwide, the incidence rates of skin cancer, like other types of cancer, is increasing. People in Europe and the Nordic countries are, compared to other areas of the world, at a higher risk of developing skin cancer due to their predominantly light and sun-sensitive skin type. The number of new cases of cancer in Estonia and Nordic countries has reached the same level as in sunny Australia, New Zealand and Florida. The increasing trend among Estonians to travel to southern counties is also likely to play a role in this.

27 Jan 2020

GW expands clinical trial of neoadjuvant immunotherapy for high-risk cutaneous squamous cell carcinoma

The Cutaneous Oncology Program at the George Washington University (GW) Cancer Center was selected as the first global site for a clinical trial for patients with high-risk cutaneous squamous cell carcinoma.

22 Jan 2020

Researchers identify how marijuana accelerates growth of HPV-related head and neck cancer

University of California San Diego School of Medicine researchers have identified the molecular mechanism activated by the presence of tetrahydrocannabinol (THC) - the ingredient that causes people to feel the euphoria or "high" associated with cannabis - in the bloodstream that accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck squamous cell carcinoma.

13 Jan 2020

Squamous Cell Carcinoma News and Research

Further Reading

Moffitt scientists identify potential therapeutic targets for cutaneous squamous cell carcinoma

Immunotherapy treatment shows promise for some patients with advanced rare cancers

Researchers find way to inactivate cancer protein with the help of another protein

Combination of radiation and immunotherapy shows promise for advanced head and neck cancers

Drug used for breast, renal cancers may provide survival benefit for patients with head and neck cancers

Researchers map the cellular diversity of entire salivary gland tumors

Cancer risk in psoriatic patients

IU researcher identifies new genomic regions that increase skin cancer risk

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Racial, socioeconomic disparities found among patients with HPV-positive oropharyngeal cancer

UArizona receives $6.9 million grant to make advances in skin cancer prevention and treatment

RNA affecting skin cancer progression discovered

Study looks into the virome of early stage, p16-positive OPSCC and neck metastasis

Researchers develop new isolated limb infusion method for melanoma treatment

GW expands clinical trial of neoadjuvant immunotherapy for high-risk cutaneous squamous cell carcinoma

Researchers identify how marijuana accelerates growth of HPV-related head and neck cancer

Melanoma patients report 95% satisfaction rate with Mohs surgery

Bariatric surgery linked to reduction in malignant skin cancer risk

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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