Steatosis News and Research

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Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

An international study has discovered that people living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time.

17 Jul 2024

CePA: Novel nanomedicine for alleviating MASH via mTOR repression

Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic liver diseases, primarily caused by metabolic disorders and systemic inflammatory responses.

16 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Aging aggravates liver fibrosis in Down Syndrome, new study finds

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 12, entitled, "Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome."

10 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Short-term alcohol abstinence worsens gut health in alcohol use disorder patients

A study published in PLoS ONE found that short-term abstinence from alcohol in AUD patients exacerbates gut dysbiosis and increases mental distress, contrary to expected improvements.

14 Jun 2024

Melatonin shows promise in preventing obesity, study finds

Two international studies led by the University of Granada (UGR) have confirmed that melatonin helps prevent obesity.

16 Apr 2024

To ban or not to ban, the case for reformulating ultra-processed foods

Despite concerns about ultra-processed foods (UPFs) and non-communicable diseases (NCDs), evidence of causality remains unclear; reformulating UPFs may offer significant health advantages.

1 Apr 2024

Quibim introduces QP-Liver for enhancing liver disease diagnosis through MRI analysis

Quibim, a global company pioneering imaging biomarkers for precision medicine, is today announcing the launch of a new product, QP-Liver, which improves the diagnosis of diffuse liver diseases through highly accurate quantification of tissue fat and iron from MRI scans. It has been given a CE and UKCA mark for the European Union and United Kingdom respectively, meaning it is cleared to be used in those markets.

24 Mar 2024

Exploring the role of iodine in obesity, diabetes, and other metabolic conditions

The metabolic implications of iodine consumption and elucidated the underlying mechanisms.

21 Mar 2024

Maternal obesity linked to liver cancer risk in offspring

Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern.

12 Mar 2024

Boosting curcumin's absorption and effectiveness for disease prevention and therapy

The potential of nano-formulations to boost the bioavailability and bioactivity of curcumin.

12 Mar 2024

Resistant starch diet proves a game changer for weight loss and diabetes control

Supplementation with resistant starch leads to weight loss and improved insulin sensitivity by altering the gut microbiome and increasing secondary bile acids, according to a recent study in Nature Metabolism.

27 Feb 2024

Beyond just a berry: The multifaceted health benefits of black chokeberry

Review highlights the potential of black chokeberry (Aronia melanocarpa) in disease control and prevention, focusing on its rich polyphenol content and the diverse mechanisms through which it exerts anti-disease properties on the human body.

12 Feb 2024

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Whether higher dietary niacin intake lowers the risk of all-cause, heart and cerebrovascular disease(s).

6 Feb 2024

Noninvasive diagnostic tool for identification of NASH by visualizing hepatic steatosis and inflammation

Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated fatty liver disease (MAFLD), is spectrum of diseases that ranges from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).

26 Jan 2024

Dietary carotenoids may reduce risk of non-alcoholic fatty liver disease, study suggests

Study found no direct link between total dietary vitamin A intake and non-alcoholic fatty liver disease (NAFLD) risk, but observed an inverse correlation between provitamin A carotenoid consumption and NAFLD risk.

23 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).