Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

First-of-its-kind study examines whether fat tissues from different areas of the body vary in stem cell concentration

Fat removed from the lower abdomen and inner thigh through liposuction was found to be an excellent source of stem cells, with higher stem cell concentrations than other areas of the body, reports a Brazilian-based study in August's Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

23 Jul 2008

Notch protein helps human embryonic stem cells 'decide' their own fate

Researchers at Johns Hopkins have discovered that the Notch protein helps human embryonic stem cells 'decide' their own fate, a finding which may eventually be useful in programming cells for the development of stem cell therapies. Their results are reported in the May 2008 issue of Cell Stem Cell.

22 Jul 2008

Discovery of cells for spinal-cord repair

A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries.

22 Jul 2008

Stem cell chicken and egg debate moves to unlikely arena: the testes

Logic says it has to be the niche. As air and water preceded life, so the niche, that hospitable environment that shelters adult stem cells in many tissues and provides factors necessary to keep them young and vital, must have emerged before its stem cell dependents.

20 Jul 2008

Functional human blood vessels grown in mice using cells from adult human donors

For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors - an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association.

19 Jul 2008

Standards in stem cell research

Standards in stem cell research help both scientists and regulators to manage uncertainty and the unknown, according to new research funded by the Economic and Social Research Council. Efforts to standardise practices across different labs is, however, a balancing act where the autonomy of scientists and fragility of living material need to be weighed against the need for comparable data.

17 Jul 2008

New ultrasound imaging system spots early evidence of peripheral arterial disease

Researchers at Oregon Health & Science University have devised an ultrasound imaging technique that picks up subtle early evidence of peripheral arterial disease (PAD) that current conventional tests miss.

17 Jul 2008

New technology revolutionizing drug discovery

The National Science Foundation has awarded Weill Cornell Medical College researcher Dr. Scott Blanchard its prestigious Career Award, recognizing his groundbreaking work in cell biology -- work that is poised to revolutionize research for the next generation of young scientists.

15 Jul 2008

Stem cells help keep the brain healthy and active

For some years, scientists have been speculating over why stem cells exist in the brain, as brain regeneration is limited. A German team of neuroscientists believe these stem cells help keep the brain healthy and active.

13 Jul 2008

Proof-of-concept that purified muscle stem cells can be used in therapy

By injecting purified stem cells isolated from adult skeletal muscle, researchers have shown they can restore healthy muscle and improve muscle function in mice with a form of muscular dystrophy. Those muscle-building stem cells were derived from a larger pool of so-called satellite cells that normally associate with mature muscle fibers and play a role in muscle growth and repair.

10 Jul 2008

Potential new way to prevent graft-versus-host disease

A new University of Michigan study in mice suggests that a drug recently approved to fight cancer tumors is also able to reduce the effects of graft-versus-host disease, a common and sometimes fatal complication for people who have had bone marrow transplants.

10 Jul 2008

Scientists identify 22 genes that control embryonic stem cell fate

Scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The limbo lies between the embryonic stage and fully differentiated, or specialized, cells, such as bone, muscle or fat.

10 Jul 2008

Stopping drinking may lead to health problems including depression

Scientific evidence has long suggested that moderate drinking offers some protection against heart disease, certain types of stroke and some forms of cancer.

8 Jul 2008

Stem Cell Sciences granted UK patent for new growth medium for authentic embryonic stem cells

Stem Cell Sciences plc today announced that the UK Patent Office has granted it a patent covering the Company's new range of stem cell culture media. The new Culticell iSTEM range uses the inhibitor based technology discovered by Professor Austin Smith and recently published in Nature (vol. 453, pp.519-523).

8 Jul 2008

Japanese encephalitis damages the brain in two ways

Japanese encephalitis (JE), commonly known as brain fever, is one of the prevalent mosquito-borne encephalitis in India and entire South East (SE) Asia.

8 Jul 2008

Discovery of new function for an old enzyme in sialidosis

The lack of a single protein usually thought of as a run-of-the-mill enzyme that helps to recycle molecules in cells causes an incurable and often fatal disease of children, according to St. Jude Children's Research Hospital investigators.

7 Jul 2008

New method to evaluate variations identified in breast cancer susceptibility genes

Using mouse embryonic stem cells, researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have developed a new method to evaluate which mutations, or changes, in a gene known to increase breast cancer susceptibility, may lead to cancer. The new test, called a functional assay, is more comprehensive and reliable than most current methods.

7 Jul 2008

Scientists shed new light into early mechanisms governing cardiovascular specification

The mature heart is composed by different cell types, including contractile cardiac cells, vascular cells, smooth muscle cells as well as pacemaker cells.

3 Jul 2008

Statins have unexpected effect on pool of powerful brain cells

Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

3 Jul 2008