Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Making sense of the data in a controversial trial of a "clot-busting drug" for treating stroke

In December 1995, a highly controversial trial was published, which tested a clot-busting drug called rt-PA (recombinant tissue plasminogen activator) in patients who had suffered an acute stroke.

20 May 2008

Minocycline may find new life as a stroke treatment

An old intravenous antibiotic may have new life as a stroke treatment, researchers say. Minocycline appears to reduce stroke damage in multiple ways - inhibiting white blood cells and enzymes that, at least acutely, can destroy brain tissue and blood vessels, respectively, says Dr. David Hess, chair of the Department of Neurology in the Medical College of Georgia School of Medicine.

19 May 2008

Stroke plays a role in epilepsy development, especially for elderly

Seizures may be a sign of significant brain injury, and may occur in patients that experience any type of stroke. A new study finds that stroke patients with ensuing seizures are more likely to die in the 30 days following stroke than patients without seizures. The findings show a mortality rate of over 30 percent at thirty days after stroke.

19 May 2008

Thiazide-type diuretic shown to be best first-choice drug for hypertensive patients

A study based at The University of Texas Health Science Center at Houston provides added justification that a thiazide-type diuretic is the best first-choice drug for hypertensive patients. The findings, published in the American Heart Association's Circulation, Volume 117, Issue 20, evaluate the results of a previous trial coordinated by researchers at The University of Texas School of Public Health, along with other recent studies.

19 May 2008

Erection problems may signal serious heart disease

Erectile dysfunction is always a matter of the heart, but new research shows that more than romance is at stake. Two new studies of men with type 2 diabetes found that erectile dysfunction (ED) was a powerful early warning sign for serious heart disease, including heart attack and death.

19 May 2008

Bypass not to blame for heart patients' mental decline

Heart patients often experience lasting problems with memory, language, and other cognitive skills after bypass surgery. However, these problems aren't caused by the surgery itself or the pump used to replace heart function during surgery, a new study by Johns Hopkins researchers suggests. The findings may lead to better approaches to prevent cognitive decline regardless of which treatment heart disease patients receive.

19 May 2008

Treatment of obstructive sleep apnea with CPAP may lower blood pressure

Treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) may also lower blood pressure among hypertensive adults, according to researchers in Spain, who will present his findings at the American Thoracic Society's 2008 International Conference in Toronto on Sunday, May 18.

19 May 2008

Most drinkers clueless about how much alcohol a glass of wine contains

A survey carried out in Britain has revealed that most people haven't a clue how much alcohol the average glass of wine contains.

19 May 2008

Effectiveness of antiretroviral therapy causing 'complacency' among high-risk groups

HIV/AIDS clinicians and scientists have been "witness to a transformation in disease management that is virtually unprecedented in the history of medicine," Mark Wainberg, director of McGill University's AIDS Centre at Jewish General Hospital, and Julio Montaner, director of the BC Centre for Excellence in HIV/AIDS, write in a National Post opinion piece.

19 May 2008

A transgenic monkey model of Huntington's disease developed

Scientists have developed the first genetically altered monkey model that replicates some symptoms observed in patients with Huntington's disease, according to a new study funded by the National Institutes of Health. Researchers are now able to better understand this complex, devastating and incurable genetic disorder affecting the brain.

19 May 2008

Traffic pollution can be deadly as it increases the risk of deep vein thrombosis

Scientists in the U.S. have confirmed a long held suspicion that traffic pollution can be deadly for some people.

13 May 2008

Beta blockers after surgery more risky than beneficial

The results of new research has shown that patients given high doses of beta blocker drugs following non-cardiac surgery were more likely to have a stroke or die. However they were less likely to suffer a heart attack.

13 May 2008

Scientists identify heat sensing regulator - better understanding pain sensitivity

Neuroscientists at Johns Hopkins are a step closer to understanding pain sensitivity - specifically why it's variable instead of constant - having identified a gene that regulates a heat-activated molecular sensor.

12 May 2008

Think before you drink, says University research

People are being urged to think before they drink as part of a research project aimed at changing people's binge drinking habits.

12 May 2008

Discovery of mechanism of action of antibiotic able to reduce neuronal cell death in brain

Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer's disease, Huntington's disease, epilepsy, stroke, dementia and malignant gliomas.

11 May 2008

Childhood and adolescent obesity impacts cardiac health

Study findings presented at the May 2008 Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting indicate that childhood and adolescent obesity negatively impacts vascular endothelial function, which relates to cardiac health.

11 May 2008

New guidelines say botulinum toxin effective for many neurological disorders, but not headache

New guidelines developed by the American Academy of Neurology confirm that the drug botulinum toxin is safe and effective for treating a variety of neurological conditions. Surprisingly, the drug may not be effective for chronic headaches, accrding to Allison Brashear, M.D., professor and chairman of the Department of Neurology at Wake Forest University Baptist Medical Center, who helped develop the guidelines.

9 May 2008

Study finds darapladib lowers biomarker for cardiovascular problems

Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and block blood flow. The drug darapladib may offer a way to fight that risk, according to new research led by the University of Pennsylvania School of Medicine.

8 May 2008

Medicare fee cuts could devastate rehabilitation services

Pending cuts to the Medicare physician fee schedule could severely hamper the ability of physical therapists to serve the rehabilitation needs of seniors and people with disabilities -- driving up overall costs while decreasing quality of care, according to the American Physical Therapy Association (APTA) and its Private Practice Section.

8 May 2008

New journal - Circulation: Heart Failure

The American Heart Association has named the editor of Circulation: Heart Failure, its second of the planned six-publication extension to the weekly flagship journal, Circulation: Journal of the American Heart Association. The journals will be published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

7 May 2008