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Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Following the success of their ongoing alliance, Boehringer Ingelheim and the University of Dundee extend their collaboration to develop new medicines that target and destroy key cancer causing proteins.

12 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

New research training group established at MLU for protein research

A new research training group will start conducting research on proteins at the Martin Luther University Halle-Wittenberg in June 2019.

30 May 2019

Newly identified internal regulator helps control body's response to fight infection

Scientists have identified a new internal regulator which helps control the body's response to fight infection.

30 May 2019

Research into structure of anticoagulant protein may open new avenues for treatment of thrombosis

A collaboration between researchers from Brazil and the United States may open new avenues for the treatment of thrombosis, the leading cause of death among cancer patients.

27 May 2019

Electron microscopy project could revolutionize the search for new drugs

The search for new drugs to combat diseases more effectively could be revolutionized through a new £30 million electron microscopy project.

17 May 2019

NIH announces awards to advance development of vaccines for sexually transmitted infections

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, today announced awards to establish four Cooperative Research Centers focused on developing vaccines to prevent sexually transmitted infections.

10 May 2019

Biophysicists study structure of KR2 rhodopsin under physiological conditions

A team of biophysicists from Russia, Germany, and France, featuring researchers from the Moscow Institute of Physics and Technology, has discovered and studied the structure of the KR2 rhodopsin under physiological conditions.

8 May 2019

Researchers use structural biology techniques to understand how lipids bind proteins

Normal cells have a complex system of checks and balances that regulate cell division.

30 Apr 2019

Researchers discover how an executioner mechanism is triggered to kill damaged cells

Researchers led by St. Jude Children's Research Hospital structural biologists have discovered how the cell switches on an executioner mechanism called necroptosis that induces damaged or infected cells to commit suicide to protect the body.

27 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Neuronal transport factor detects its target transcripts in more complex manner than previously thought

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought.

16 Apr 2019

High levels of blood lipids may worsen multiple sclerosis symptoms in obese patients

A newly published paper in the Lancet journal EBioMedicine identifies a link between high levels of blood lipids and worsening of disease in multiple sclerosis patients who are overweight or obese.

12 Apr 2019

Scientists solve mystery surrounding common genetic cause of ALS

St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis, or Lou Gehrig's disease.

11 Apr 2019

Bruker announces innovative UHF magnet technology for high-resolution NMR in structural biology

At the 60th Experimental Nuclear Magnetic Resonance Conference (ENC, www.enc-conference.org ), Bruker announced today a breakthrough in ultra-high field high-resolution NMR spectroscopy applied to structural biology and the study of functional intrinsically disordered proteins.

From Bruker BioSpin - NMR, EPR and Imaging 10 Apr 2019

‘Hit-and-run’ interaction between proteins appears to be key trigger for cell death

A 'hit-and-run' interaction between two proteins could be an important trigger for cell death, according to new research from Walter and Eliza Hall Institute researchers.

10 Apr 2019

Researchers aim to identify potential new drugs for wide range of diseases using AI

A half dozen University of Connecticut researchers are now working to identify potential new drugs to treat a wide range of diseases and conditions through a unique partnership that offers access to cutting-edge artificial intelligence technology and screening compounds at no cost.

10 Apr 2019

New Research Unit funded by DFG aims to improve diagnosis of genetic diseases

How can we improve the identification and prompt diagnosis of genetic diseases? A new Research Unit at Charité - Universitätsmedizin Berlin will set out to identify and reliably interpret important non-coding sections of our genomes in the hope of finding the diagnosis for unsolved diseases.

5 Apr 2019

New class of molecules could someday become basis for Zika-specific therapeutic

The Zika virus is widely known for causing microcephaly and other brain defects in the fetuses of pregnant, infected women.

4 Apr 2019

Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.