Structural Biology News and Research

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Scientists elucidate 3D structure of protein involved in cancer

The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses.

6 Jun 2018

Detailed structure of protein pair offers blueprint for new medicines

Walter and Eliza Hall Institute researchers have visualized for the first time how the protein SOCS1 'switches off' cell signaling to dampen immune responses and block cancer growth.

4 Jun 2018

Researcher develops small molecules that inhibit derailment of gene expression in cancer

Not everyone person who has a "cancer gene" will inevitably develop this disease in their lifetime. Thanks to a new area of research called epigenetics, we now know that many genes are only read under certain circumstances.

17 May 2018

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research.

16 May 2018

Biochemists isolate protein supercomplex from bacteria that generates voltage

Biochemists at the University of Illinois have isolated a protein supercomplex from a bacterial membrane that, like a battery, generates a voltage across the bacterial membrane.

15 May 2018

3D structures of nicotine receptor could lead to new ways for treating addiction

UT Southwestern researchers today published in Nature atomic-scale blueprints of the most abundant class of brain nicotinic acetylcholine receptors. A structural understanding of the protein, found in neurons, could lead to new ways to treat nicotine addiction from smoking and vaping.

3 May 2018

Scripps Research team receives $12 million grant to improve flu and malaria vaccines

Scientists at The Scripps Research Institute aim to improve flu and malaria vaccines with the support of a new $12 million grant from the Bill & Melinda Gates Foundation.

3 May 2018

Study findings could open new possibilities for treating cancer with adenovirus

Adenovirus is a common virus that causes infectious diseases of the respiratory tract, eyes and gastrointestinal tract in humans and animals. Researchers at Umeå University study molecular mechanisms of infection in order to understand how adenovirus causes disease.

20 Apr 2018

CNIO researchers determine structure of protein complex related to cell survival

A team from the Spanish National Cancer Research Centre has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer.

16 Apr 2018

Researchers reveal molecular structure of 'anti-aging' protein

Researchers from UT Southwestern's Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Internal Medicine's Division of Nephrology recently published work in Nature that reveals the molecular structure of the so-called "anti-aging" protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic processes.

29 Mar 2018

Platypus milk may help combat antibiotic resistance

According to researchers, milk obtained from the duck-billed platypus could soon be used to fight antibiotic resistance. The new study report was published in the journal Structural Biology Communications.

18 Mar 2018

Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Research consortium develops first 3D computer model of metabolic processes

An international research consortium developed, with significant involvement of Luxembourg Centre for Systems Biomedicine scientists, the first computer model to include 3D in the representation of human metabolic processes.

22 Feb 2018

Novel motion capture-like technology for tracking how proteins fold into certain shape

In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology.

13 Feb 2018

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by prof. Savvas Savvides has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease.

18 Jan 2018

Study finds new mechanism regulating giant protein essential for muscle and heart function

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role in the function of skeletal muscle and the heart.

12 Jan 2018

Structural Biology News and Research

Scientists elucidate 3D structure of protein involved in cancer

Detailed structure of protein pair offers blueprint for new medicines

Researcher develops small molecules that inhibit derailment of gene expression in cancer

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Biochemists isolate protein supercomplex from bacteria that generates voltage

3D structures of nicotine receptor could lead to new ways for treating addiction

Scripps Research team receives $12 million grant to improve flu and malaria vaccines

Study findings could open new possibilities for treating cancer with adenovirus

CNIO researchers determine structure of protein complex related to cell survival

Researchers reveal molecular structure of 'anti-aging' protein

Platypus milk may help combat antibiotic resistance

Researchers discover key inner control mechanism of cell's 'smart glue'

Research consortium develops first 3D computer model of metabolic processes

Novel motion capture-like technology for tracking how proteins fold into certain shape

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

Study finds new mechanism regulating giant protein essential for muscle and heart function

New discovery could help treat breast cancer through precision medicine

Discovery of key protein’s structure may help improve drug design

Researchers discover ‘brake’ that interferes with HIV's development into infectious agent

University of Michigan and AstraZeneca partner to improve treatment for CKD patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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