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Scientists discover how excess oxygen changes a handful of proteins in the cells

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs.

8 Mar 2023

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

In a recent study posted to the Preprints with The Lancet SSRN* server, a team of researchers in China developed a machine learning-based diagnostic tool to detect tuberculosis and drug-resistant tuberculosis using nanoparticle-enhanced laser desorption/ionization mass spectrometry (NPELDI MS) to determine metabolic fingerprints from serum samples.

28 Feb 2023

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Scientists discover how a "poisoned" form of protein could spur cancer formation

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

Novel method for comparing whole protein-coding genes between metagenomic data detects an environmental gradient for the microbiota

Researchers from Japan compared phylogenetic trees based on proteomic data of microbiota with dendrograms of environmental factors to determine the role of environmental gradients in establishing microbial communities.

7 Feb 2023

Can reducing air pollution prevent multimorbidity?

Researchers argues for the need to more studies to identify a potential association between multimorbidity and air pollution, if it exists.

31 Jan 2023

What are the long-term effects of PM2.5 components on the prevalence of hypertension?

Researchers conducted a nationwide cross-sectional analysis of the long-term consequences of particulate matter and its five components on hypertension among participants from 13 Chinese provinces.

30 Jan 2023

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

New clue may explain why women are at greater risk for Alzheimer's disease

Scientists at Scripps Research and Massachusetts Institute of Technology (MIT) have found a clue to the molecular cause of Alzheimer's-;a clue that may also explain why women are at greater risk for the disease.

15 Dec 2022

Newly identified pathway transforms biologically inert peptide into structurally complex antibiotics

Researchers in the Princeton University Department of Chemistry have discovered a new multi-step pathway through which bacteria found in the mammalian gut produce antimicrobial peptides.

14 Nov 2022

How air pollution affects the central nervous system over time

An article published in the journal Toxics describes how air pollutants adversely impact the human nervous system.

13 Nov 2022

Children exposed to air pollution in early years more likely to develop food allergies

A new research paper explores associations between food allergies and pre- or post-natal exposure to pollutants in the air, thus paving the way for future studies on the potential sensitization of the gut by exposure of the skin or airway to pollutants, in addition to the alimentary route.

7 Nov 2022

Researchers use AI to predict compounds that could neutralize baldness

Hair loss is undesirable for many men -; and women -; because one's hairstyle is often closely tied to their self-confidence.

31 Oct 2022

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible.

12 Oct 2022

Plasma proteome signature predictive of occurrence of persistent symptoms following SARS-CoV-2 infection

In a new study, researchers performed a proteomic multiple-reaction monitoring analysis of 91 pre-selected proteins using the plasma samples of 156 healthcare workers (HCW) in the United Kingdom (UK).

30 Sep 2022

Auranofin inhibits SARS-CoV-2 replication

In a new ISCIENCE journal study, scientists identified an FDA-approved NF-κB inhibitor, Auranofin, which can also control inflammation.

6 Sep 2022

Study reveals the ill effects of common air pollutants on pregnant women and their unborn children

Mild exposure to common smog pollutants such as inhalable airborne particles and carbon monoxide during pregnancy results in adverse maternal and fetal health outcomes, a new study of women in China finds.

5 Aug 2022

Mild exposure to smog pollutants during pregnancy affects maternal and fetal health outcomes

5 Aug 2022

Latest advancements in space health and medicine

When astronauts go to outer space, microgravity, intense cosmic radiation and extreme cold can have negative impacts on their bodies and health. Scientists want to better understand the intricate details of what happens to humans in space, and they're trying to come up with ways to counteract these effects.

25 Jul 2022

DNA may act as nutritional source for E. coli

Findings of a new experiment could be helpful in understanding how DNA acts as a nutrient for gut bacteria, and its impact on the health of the host.

18 Jul 2022