Supercoiling News and Research

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New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

Fungal endophytes: A promising frontier for breast cancer treatment

Fungal endophytes: A promising frontier for breast cancer treatment

Study reveals how DNA gyrase resolves DNA entanglements

Study reveals how DNA gyrase resolves DNA entanglements

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

UVA researchers solve a decades-old mystery about how bacteria can move

UVA researchers solve a decades-old mystery about how bacteria can move

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

Supercoiling and looping can transmit mechanical stress along the DNA backbone, research shows

Harnessing DNA’s properties to craft “‘topologically tunable” DNA-based materials

Harnessing DNA’s properties to craft “‘topologically tunable” DNA-based materials

DNA supercoiling is involved in the control of gene expression

DNA supercoiling is involved in the control of gene expression

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

Critical mechanism allows deadly bacteria to gain resistance to antibiotics

DNA sequences encode information in many different ways

DNA sequences encode information in many different ways

There is a new twist on the question of how biological clocks work

There is a new twist on the question of how biological clocks work

Antitumour drugs impede DNA uncoiling by topoisomerase I

Antitumour drugs impede DNA uncoiling by topoisomerase I

Magnetic nano tweezers show how cancer drug works

Magnetic nano tweezers show how cancer drug works

Proteins transform DNA into molecular velcro

Proteins transform DNA into molecular velcro

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