Surgery News and Research

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SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

A unique, targeted anti-cancer drug appears to show promise against neuroendocrine tumors-stubborn cancers that have traditionally responded poorly to chemotherapy, according to research findings announced at the 2005 Annual Meeting of the American Society of Clinical Oncology (ASCO).

17 May 2005

Patients with suspicious axillary lymph nodes in their breasts should first undergo ultrasound-guided fine-needle aspiration to avoid unnecessary surgery

Currently, breast cancer patients undergo axillary lymph node dissection for accurate staging and control of the cancer. In many cases, this major procedure can be replaced by sentinel lymph node biopsy, which is a more simple and less invasive surgical procedure, but many still have to undergo axillary dissection after the sentinel lymph node biopsy.

17 May 2005

Expandable electrodes safe and effective for radiofrequency ablation of liver tumors

The use of expandable electrodes with multiple tips in the treatment of liver tumors by radiofrequency ablation (RFA) is safe and effective, making it a useful alternative to surgery in selected patients, say researchers from the University of Brescia in Italy.

17 May 2005

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Ulcerative colitis affects about one out of every 2,000 Americans, and after living with the disease for 30 years, nearly 22 percent of those people will develop colon cancer.

16 May 2005

Identifying high-risk prostate cancer means more prudent treatment decisions

While prostate cancer is a very common diagnosis, it is a deadly disease in relatively few men. One in 6 men will develop prostate cancer during his lifetime. However, of these, only one in 10 cases will be life-threatening.

16 May 2005

High-risk for melanoma patients no more likely to take proper precautions in the sun

Those considered high-risk for melanoma--the most dangerous form of skin cancer--are no more likely to sunbathe protected than those who are unaware of their risk, according to a new study conducted by McGill University Health Centre (MUHC) researchers.

16 May 2005

Improvements in critical care decrease risk of post-injury multiple organ failure

Improvements in critical care and decreased use of blood transfusions over the course of the last decade are associated with decreases in the rate, severity and risk of death from post-injury multiple organ failure, according to a study in the May issue of Archives of Surgery.

16 May 2005

Survival rates higher for children receiving living donor liver transplant

Children who undergo liver transplantation have better survival rates with living donor liver transplant graft than with deceased donor organ transplant, although factors other than the type of graft also are important, according to a study in the May issue of Archives of Surgery.

16 May 2005

New study demonstrates high rates of tumor death in patients receiving regimen

A new pilot study suggests that treating soft-tissue sarcoma with a new regimen of intense chemotherapy and a short course of radiation before surgery may be beneficial. About 41 percent of study participants were found to have complete tumor death at the time of surgery.

16 May 2005

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

A targeted cancer drug given with low-dose chemotherapy shrank ovarian tumors and slowed progression of ovarian cancer in patients with recurrent disease, according to research findings presented by Agustin Garcia, M.D., principal investigator of the study and Director of Breast Cancer Research at the Women's Cancer Research Institute at the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center.

16 May 2005

The American College of Surgeons publishes manual on surgical patient safety

The American College of Surgeons (ACS) has announced the publication of its new manual Surgical Patient Safety: Essential Information for Surgeons in Today's Environment. Edited by Barry M. Manuel, MD, FACS, and Paul F. Nora, MD, FACS, the manual is intended to provide guidance and leadership in evolving areas of patient safety in the surgical profession.

16 May 2005

Colon cancer patients who took aspirin regularly fared better after surgery

Colon cancer patients who took aspirin regularly fared better after surgery, reducing their risk of disease recurrence and death by half compared to non-users, researchers will report at the annual meeting of the American Society of Clinical Oncology.

16 May 2005

Study shows the longest reported survival rate for patients with locally advanced lung cancer

Five-year data from a study evaluating the use of docetaxel (Taxotere) administered after cisplatin/etoposide chemotherapy plus radiation therapy demonstrate the best long-term survival rates reported in patients with locally advanced (Stage IIIB) non-small cell lung cancer (NSCLC).

16 May 2005

Botox injections decrease drooling in children with neurologic impairments

Ultrasound-guided Botox injections into the salivary glands decrease drooling in children with neurologic impairments such as cerebral palsy, say researchers from Toronto’s Hospital for Sick Children.

16 May 2005

Taxotere shows significant survival benefit in the treatment of advanced gastric cancer

Final results from the largest international study in the treatment of advanced stomach cancer, also known as gastric cancer, demonstrated that patients who received a Taxotere (docetaxel) Injection Concentrate-based chemotherapy regimen (Taxotere, cisplatin and 5-fluorouracil) had significantly improved overall survival rates compared to patients who received a standard treatment (cisplatin and 5- fluorouracil).

16 May 2005

Zometa reduces bone loss in patients receiving breast cancer treatment

Data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida, demonstrate that Zometa (zoledronic acid), an intravenous bisphosphonate, was shown to inhibit bone loss in postmenopausal women treated with Femara (letrozole) in the adjuvant breast cancer setting (directly following surgery to prevent cancer recurrence).

16 May 2005

Black children are more than twice as likely to die from a traumatic injury as are white children

“Trauma has a far greater impact on minority children than it does on white children,” said Jonathan Groner, the study's lead author and a clinical associate professor of surgery at Ohio State University . “As a group, black children tend to have more serious injuries.”

15 May 2005

Tonsil swabbing is terrible - it makes people gag

Mayo Clinic ear, nose and throat surgeons hoped to find a more user-friendly test for strep throat than swabbing the tonsils directly, but instead discovered that the swab has to touch the tonsils to accurately detect the infection.

15 May 2005

Research findings help predict risk of blood clots in women receiving tamoxifen therapy for breast cancer

New research findings may help physicians determine which women have an increased risk of blood clots when taking tamoxifen for the management of breast cancer, a team led by Dana-Farber Cancer Institute investigators will report at the American Society of Clinical Oncology's annual meeting.

15 May 2005

Surgical technique provides the first permanent solution to treating vocal-cord spasms

The first large, long-term study of patients who had surgery to control vocal-cord spasms showed excellent results in the majority of cases, reports new UCLA research presented May 14 at the 126th Annual Meeting of the American Laryngological Association.

15 May 2005

Surgery News and Research

SU11248 drug show promise against neuroendocrine tumors-stubborn cancers that respond poorly to chemotherapy

Patients with suspicious axillary lymph nodes in their breasts should first undergo ultrasound-guided fine-needle aspiration to avoid unnecessary surgery

Expandable electrodes safe and effective for radiofrequency ablation of liver tumors

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Identifying high-risk prostate cancer means more prudent treatment decisions

High-risk for melanoma patients no more likely to take proper precautions in the sun

Improvements in critical care decrease risk of post-injury multiple organ failure

Survival rates higher for children receiving living donor liver transplant

New study demonstrates high rates of tumor death in patients receiving regimen

Bevacizumab (Avastin) combined with low-dose chemotherapy slows ovarian cancer

The American College of Surgeons publishes manual on surgical patient safety

Colon cancer patients who took aspirin regularly fared better after surgery

Study shows the longest reported survival rate for patients with locally advanced lung cancer

Botox injections decrease drooling in children with neurologic impairments

Taxotere shows significant survival benefit in the treatment of advanced gastric cancer

Zometa reduces bone loss in patients receiving breast cancer treatment

Black children are more than twice as likely to die from a traumatic injury as are white children

Tonsil swabbing is terrible - it makes people gag

Research findings help predict risk of blood clots in women receiving tamoxifen therapy for breast cancer

Surgical technique provides the first permanent solution to treating vocal-cord spasms

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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