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Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children's Hospital has revealed that an immune protein impacts neuronal protein synthesis in the aging brain.

15 Jul 2024

New technology reveals the critical role of sleep in infant brain development

Researchers have developed advanced technology to measure neonatal sleep patterns, revealing how sleep significantly impacts brain development before and after birth.

8 Jul 2024

Breakthrough in auditory research: Supranormal hearing achieved

A study from Michigan Medicine's Kresge Hearing Research Institute was able to produce supranormal hearing in mice, while also supporting a hypothesis on the cause of hidden hearing loss in humans.

28 Jun 2024

KU researchers uncover role of Src gene in nervous system development

Many people are familiar with oncogenes -; genes long known to be involved in cancers in humans, such as the gene "Src."

24 Jun 2024

How ketone bodies contribute to brain health and memory preservation

The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice.

17 Jun 2024

MIT researchers develop revolutionary system for high-resolution brain imaging

A suite of three innovations by an MIT-based team enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution.

13 Jun 2024

Revolutionary platform unveils detailed human brain architecture at multiple scales

A new platform enables simultaneous capture of protein expression, cellular morphology, neural projection, and synapse distribution in large-scale human brain tissues at multiple scales, researchers report.

13 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Targeting synaptic lipid signaling: A novel approach to mental health treatment

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders.

6 Jun 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

23 May 2024

Breakthrough ATP sensor sheds light on cellular energy dynamics

A molecule called adenosine triphosphate (ATP) is the basic unit of biochemical energy that fuels the activities of all cells.

17 May 2024

Brain cell connections weakened during first half of sleep, study reveals

During sleep, the brain weakens the new connections between neurons that had been forged while awake – but only during the first half of a night's sleep, according to a new study in fish by UCL scientists.

2 May 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Exploring the versatile roles of tissue macrophages beyond immune defense

The role of resident tissue macrophages (RTMs) in homeostasis and disease.

17 Apr 2024

Research offers first insights into the mechanism behind synaptic development

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders.

28 Mar 2024

Paper-based sensor that operates like the brain paves way for AI-based health monitoring devices

From creating images, generating text, and enabling self-driving cars, the potential uses of artificial intelligence (AI) are vast and transformative.

11 Mar 2024

Kobe University study identifies FAM81A as key player for synaptic function

A protein that appears in postsynaptic protein agglomerations has been found to be crucial to their formation.

7 Mar 2024

Study reveals surge of a neural-specific protein as the earliest-yet biomarker for Alzheimer's disease

A surge of a neural-specific protein in the brain is the earliest-yet biomarker for Alzheimer's disease, report University of Illinois Urbana-Champaign researchers studying a mouse model of the disease.

6 Mar 2024