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Chromatin accessibility as an early marker of severe COVID-19

A new study explores the possible use of chromatin remodeling in predicting a severe clinical trajectory for COVID-19.

11 Apr 2022

COVID-19 vaccines and reports of menstrual disorders

A new study estimates the potential relationship between COVID-19 vaccines and menstrual disorders.

11 Apr 2022

Researchers make progress to develop a drug for treating metabolic syndrome

Metabolic syndrome increases a person's risk for diabetes, heart disease, and stroke, and includes conditions such as obesity, high blood pressure and high blood sugar.

11 Apr 2022

NK cells combined with bispecific antibody achieve effective responses in patients with lymphoma

Researchers from The University of Texas MD Anderson Cancer Center showed that natural killer (NK) cells derived from donated umbilical cord blood, combined with a novel bispecific antibody known as AFM13 that targets CD16A and CD30, achieved effective responses in patients with pretreated and refractory CD30+ lymphoma.

11 Apr 2022

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Scientists have discovered a new generation of angiotensin receptor blockers that may be used to treat coronavirus disease 2019.

11 Apr 2022

Safety profile of colchicine in COVID-19 patients

Researchers evaluated the use of colchicine in COVID-19 patients.

11 Apr 2022

Pre-infection stress may increase the risk of long COVID and specific long COVID symptoms

Researchers predicted the development of long COVID and its three specific symptoms - difficulty with mobility, cognition, and self-care, based on the adversity experiences and worries about adversity experiences.

11 Apr 2022

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Researchers tested whether a subunit vaccine could generate mucosal immunity in mice and prevent SARS-CoV-2 infection and related pathology.

11 Apr 2022

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

Researchers performed high-throughput evolutionary analyses of genes encoding 334 SARS-CoV-2 viral-interacting proteins of modern humans, primates, and bats.

11 Apr 2022

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

A new study illustrated that inadequate population immunity exacerbated the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Hong Kong.

11 Apr 2022

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

Researchers evaluated the human antibody response to the NTD of the S protein by investigating a group of individuals who had previously been infected with SARS-CoV-2 or who had received an mRNA vaccine.

11 Apr 2022

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

A new study depicted plant-based biologically active antiviral agents that are effective against SARS-CoV-2 infection.

11 Apr 2022

Study demonstrates multinuclear MRI is sensitive to functional pulmonary changes in the follow up of patients hospitalized with COVID-19

In this study, researchers subjected patients to a pulmonary 1H and 129Xe MRI protocol at 6, 12, 25, and 50 weeks after hospitalization.

11 Apr 2022

Efficacy of miniaturized electrostatic precipitator respirators in removal of SARS-CoV-2 bioaerosols compared to N95 masks

Researchers developed a prototype of a miniaturized electrostatic precipitator that can be used as an apparatus to effectively remove SARS-CoV-2 containing bioaerosols.

11 Apr 2022

Study explores COVID-19 vaccine hesitancy among those with underlying medical conditions

In a recent study posted to the medRxiv* preprint server, researchers examined the coronavirus disease 2019 (COVID-19) vaccine uptake and hesitancy among people with chronic or severe health conditions.

11 Apr 2022

New research on SARS-CoV-2 Omicron variant mutations and sotrovimab therapy

A recent study posted to the medRxiv* preprint server assessed the impact of sotrovimab treatment on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant-infected immunocompromised (IC) patients.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

In a recent study posted to the medRxiv* preprint server, researchers reported coronavirus disease 2019 (COVID-19) prognosis worsened by the presence of cardiovascular diseases (CVDs) in pregnant and postpartum women.

11 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

Syndrome News and Research

Chromatin accessibility as an early marker of severe COVID-19

COVID-19 vaccines and reports of menstrual disorders

Researchers make progress to develop a drug for treating metabolic syndrome

NK cells combined with bispecific antibody achieve effective responses in patients with lymphoma

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Safety profile of colchicine in COVID-19 patients

Pre-infection stress may increase the risk of long COVID and specific long COVID symptoms

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Exploring evolutionary trajectories of SARS-CoV-2 interacting proteins in bats and primates

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Study explores phytochemical-based antivirals against SARS-CoV-2 infection

Study demonstrates multinuclear MRI is sensitive to functional pulmonary changes in the follow up of patients hospitalized with COVID-19

Efficacy of miniaturized electrostatic precipitator respirators in removal of SARS-CoV-2 bioaerosols compared to N95 masks

Study explores COVID-19 vaccine hesitancy among those with underlying medical conditions

New research on SARS-CoV-2 Omicron variant mutations and sotrovimab therapy

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

Immunocompromised hosts with Delta/Omicron co-infections

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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