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New cell-free antibody generation platform successfully creates neutralizing antibodies effective against SARS-CoV-2

Researchers from the Broad Institute of MIT and Harvard have created a cell-free nanobody engineering platform that can produce antibodies effectively and quickly.

21 Sep 2021

Decline in SARS-CoV-2 neutralizing antibodies and unique cytokine profile in severe COVID-19 patients

A new study has focused on antibody levels and cytokine profiles of COVID-19 patients with mild symptoms, pneumonia, and severe pneumonia.

21 Sep 2021

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

An opinion article aims to provide evidence that SP could be the possible factor for initiating the cytokine storm during severe SARS-CoV-2 infection.

21 Sep 2021

Maintenance dialysis patients may need additional shots of COVID-19 vaccines

Researchers in the United States have conducted a study showing that the antibody response to vaccination designed to protect against coronavirus disease 2019 (COVID-19) wanes substantially over time among patients receiving maintenance dialysis.

21 Sep 2021

Count of severe COVID-19 no higher in children during second wave compared to first wave

Researchers in the UK have conducted a study suggesting that severe disease in children and young people admitted to hospital following infection with severe acute respiratory syndrome coronavirus (SARS-CoV-2) is still rare and was no more common during the second wave of infections than the first.

21 Sep 2021

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

In a recently published article on the bioRxiv* preprint server, scientists from the USA and UK have described the significance of early inflammatory signaling pathways in determining the severity of coronavirus disease 2019 (COVID-19).

21 Sep 2021

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Scientists hypothesize SARS-CoV-2 cryptically circulating among humans before the current outbreak

As nations begin to recover, researchers from the National Taiwan University and Academia Sinica in Taipei have been looking to identify the changes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underwent over the course of the pandemic in order to better understand why the disease showed such virulence.

20 Sep 2021

Drugs and surgery show promise for reducing long-term effects of obesity-related hypertension

Weight-loss medications and surgical procedures show promise for reducing the long-term effects of high blood pressure (also called hypertension) in people who are overweight or have obesity, according to a new American Heart Association scientific statement published today in the Association's journal Hypertension.

20 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

A novel FACS-based approach for SARS-CoV-2 serology

A recent study discusses a simple, sensitive, and quantitative serological test based on FACS assay to evaluate antibodies against SARS-CoV-2.

20 Sep 2021

Role of extracellular vesicles embedded with engineered ACE2 in the neutralization of the SARS-CoV-2 pseudovirus

Researchers discuss the preparation and characterization of EVs-ACE2, along with the production and characterization of SARS-CoV-2 S-pseudovirus.

20 Sep 2021

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

A new study proposes an integrative computational approach to model the structure of the SARS-CoV-2 envelope.

20 Sep 2021

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Researchers complete an extensive search on previously published studies to understand the efficacy of convalescent plasma in treating COVID-19.

20 Sep 2021

Study examines relationship between public health behavior and social capital indices during COVID

A recent study examines the relationship among public health behaviors during the COVID-19 pandemic and social capital indices in the United States.

20 Sep 2021

Role of host gene variants in COVID-19 severity

A new study discusses the importance of common, rare, and intermediate variants of several host genes to the clinical severity of infection with SARS-CoV-2.

20 Sep 2021

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

A new study finds that hypertension following the viral infection is associated with high placental viral load in pregnant women with COVID-19.

20 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Asymptomatic SARS-CoV-2 infections vary with age and geographical location

In this study, surveillance data were used to investigate how asymptomatic SARS-CoV-2 infections vary by age and geographic location.

20 Sep 2021

What impact has SARS-CoV-2 variant B.1.1.519 had on Mexico City?

The current study reports the effective reproduction number of B.1.1.519 and presents its geographical origin based on phylogenetic analysis.

20 Sep 2021

Syndrome News and Research

New cell-free antibody generation platform successfully creates neutralizing antibodies effective against SARS-CoV-2

Decline in SARS-CoV-2 neutralizing antibodies and unique cytokine profile in severe COVID-19 patients

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Maintenance dialysis patients may need additional shots of COVID-19 vaccines

Count of severe COVID-19 no higher in children during second wave compared to first wave

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Scientists hypothesize SARS-CoV-2 cryptically circulating among humans before the current outbreak

Drugs and surgery show promise for reducing long-term effects of obesity-related hypertension

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

A novel FACS-based approach for SARS-CoV-2 serology

Role of extracellular vesicles embedded with engineered ACE2 in the neutralization of the SARS-CoV-2 pseudovirus

Scientists simulate SARS-CoV-2 virion envelope using Martini 3

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Study examines relationship between public health behavior and social capital indices during COVID

Role of host gene variants in COVID-19 severity

Hypertension in COVID-19-affected pregnancy linked to high SARS-CoV-2 load in placenta

T cell immunity induced after mild COVID could contribute to protection against re-infection

Asymptomatic SARS-CoV-2 infections vary with age and geographical location

What impact has SARS-CoV-2 variant B.1.1.519 had on Mexico City?

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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