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Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

A new study, released as a preprint on bioRxiv* server, shows that a combination of the biological interferon-α and the small molecule nafamostat are effective against SARS-CoV-2 infection in vitro, as well as in vivo.

18 Jun 2021

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

A new study, released as a preprint on the bioRxiv* server, reveals the high neutralizing efficacy of hyperimmune horse serum against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could prove, if validated, to be a more affordable yet potent therapeutic in reducing the morbidity and mortality caused by this virus.

18 Jun 2021

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Despite tremendous efforts by the global scientific community to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by developing more efficient testing protocols, therapies, and vaccines at a rapid pace, relatively little is known about the dynamics of SARS-CoV-2 replication within cells.

18 Jun 2021

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19.

18 Jun 2021

Convalescent plasma can improve chances of survival among blood cancer patients with COVID-19

A large, retrospective, multicenter study involving Washington University School of Medicine in St. Louis indicates that convalescent plasma from recovered COVID-19 patients can dramatically improve likelihood of survival among blood cancer patients hospitalized with the virus.

18 Jun 2021

Which vitamins and minerals help with COVID?

A study published in the journal Inflammopharmacology reviewed recent data related to the role of vitamins and minerals in treating COVID-19 patients. The primary goal of the review is to highlight the possible therapeutic role of vitamins A, B, C, D, E and K, and micronutrients as immunity boosters in COVID-19 patients.

18 Jun 2021

$Researchers report a new genetic cause for infantile fractures$

Researchers report a new genetic cause for infantile fractures

An intrauterine fracture is a rare finding during routine prenatal imaging. This condition can be due to maternal trauma, genetic disorders of the skeleton, as well as other predisposing maternal metabolic and vascular disorders.

18 Jun 2021

The SARS-CoV-2 virus and its vaccines pose unique challenges

Iranian researchers recently provided a review of the attempts made to develop safe SARS-CoV-2 vaccines. The researchers outlined potential challenges and concerns, including disease enhancement, virus mutation, and public acceptability. Their work is published in the journal Immunological Investigations.

18 Jun 2021

Alarming COVID study indicates long-term loss of gray matter and other brain tissue

In a research paper recently uploaded to the preprint server medRxiv* by Prof. Gwenaëlle Douaud et al. (June 15th, 2021), participants that had taken part in a brain study prior to the onset of the COVID-19 pandemic were invited back for a series of follow-up tests, revealing significant losses of grey matter surrounding the olfactory and gustatory system in those that had been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Jun 2021

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

Researchers reporting on findings from the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial in the UK are recommending that any therapeutic use of REGEN-COV may be best restricted to individuals without detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Jun 2021

The role of natural killer cells in fight against viral infections including SARS-CoV-2

In an effort to further understand the role of NK cells in combatting COVID-19, a group of researchers explored NK cells in acute viral infections, citing flavivirus and influenza virus infections as examples.

17 Jun 2021

New insight into SARS-CoV-2 mRNA vaccine breakthrough infections

In the current study, vaccine breakthrough infections were noted in 24 people who had previously received COVID-19 vaccines.

17 Jun 2021

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

A team of scientists from the United States has recently evaluated the efficacy of a ferritin nanoparticle-formulated, SARS-CoV-2 spike-based vaccine against newly emerged Variants of Concern (VOCs).

17 Jun 2021

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Researchers have found that both type I and type III interferons can inhibit SARS-CoV-2 infection in human intestinal cells, but type III interferons can act faster and for a longer period, making them suitable for potential therapeutics.

17 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

A new preprint recently released on the bioRxiv* server describes the immunogenicity and protective potential of a novel adenovirus SARS-CoV-2 vaccine candidate against a form of the virus adapted to cause severe disease in mice. The findings show that this provides a useful mouse model for the study of new vaccines, in addition to demonstrating the protective efficacy of the current rhesus adenovirus vaccine candidate RhAd52.

17 Jun 2021

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

A recent study discusses the efficacy of an AI-enhanced ECG technique that has been used to diagnose left ventricular dysfunction in COVID-19 patients.

17 Jun 2021

How the common cold can provide protection against COVID-19

In a recent study, researchers found that prior infection with the rhinovirus can provide a more effective immune response against SARS-CoV-2 infection.

17 Jun 2021

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Researchers in the United States have demonstrated the effectiveness of early treatment with REGEN-COV™ at preventing symptomatic disease among people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jun 2021

Full vaccination prevents emergency care and hospitalization in cases of breakthrough COVID-19

Researchers in the United States have demonstrated the effectiveness of the Pfizer-BioNTech, Moderna, and Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccines at reducing the need for emergency care or hospitalization following breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Jun 2021

Syndrome News and Research

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Nanodecoys made from human lung spheroid cells can neutralize SARS-CoV-2

Convalescent plasma can improve chances of survival among blood cancer patients with COVID-19

Which vitamins and minerals help with COVID?

Researchers report a new genetic cause for infantile fractures

The SARS-CoV-2 virus and its vaccines pose unique challenges

Alarming COVID study indicates long-term loss of gray matter and other brain tissue

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

The role of natural killer cells in fight against viral infections including SARS-CoV-2

New insight into SARS-CoV-2 mRNA vaccine breakthrough infections

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

How the common cold can provide protection against COVID-19

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Full vaccination prevents emergency care and hospitalization in cases of breakthrough COVID-19

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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