Systemic Lupus Erythematosus News and Research

RSS

Systemic lupus erythematosus (SLE) is the form of the disease that most people are referring to when they say "lupus." The word "systemic" means the disease can affect many parts of the body. The symptoms of SLE may be mild or serious. Although SLE usually first affects people between the ages of 15 and 45 years, it can occur in childhood or later in life as well.

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery-; successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

Patients with rheumatologic disease can safely receive life-saving cancer immunotherapy

In the largest single-center study of patients with rheumatologic diseases who were prescribed modern cancer immunotherapy with what are called immune checkpoint inhibitors, only a minority of patients experienced a flare of their rheumatologic disease or immune-related side effects.

24 Jan 2018

Study finds link between lupus and elevated risk of dementia

A new International Journal of Geriatric Psychiatry study indicates that the risk of dementia may be elevated in individuals with systemic lupus erythematosus (SLE), an autoimmune disease affecting a range of systems including the peripheral and central nervous system.

8 Nov 2017

Study shows lupus support line as valuable resource to help patients cope with disease

A free telephone support and education program for people with lupus is a valuable resource to help them cope with the disease, according to a study at Hospital for Special Surgery in New York City.

7 Nov 2017

Obesity linked to worse patient-reported outcomes in women with lupus

Obesity is independently associated with worse patient-reported outcomes in women with systemic lupus erythematosus, including disease activity, depressive symptoms, pain and fatigue, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Dietary intake of omega-3 and omega-6 fatty acids may affect outcomes in lupus patients

Higher intake of omega-3 fatty acids was associated with better sleep quality and a decrease in depressive symptoms in lupus patients, among other patient-reported outcomes, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Vitamin D insufficiency associated with higher rates of renal disease in lupus patients

Low levels of vitamin D were associated with higher rates of end-stage renal disease in patients with systemic lupus erythematosus, or lupus, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

UH professors developing new home test kit for kidney nephritis

With a four-year $1.4 million grant from the National Institutes of Health, two University of Houston engineering professors are developing a home test kit for kidney nephritis, or inflammation, in patients who have Systemic Lupus Erythematosus.

25 Oct 2017

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked.

20 Oct 2017

New guideline on care of adults with lupus published

A University of Birmingham academic has led the authorship of the UK's first guideline on the care of adults with systemic lupus erythematosus (lupus).

11 Oct 2017

Study: Lupus affects Hispanic, Asian women in Manhattan more frequently than white women

Within Manhattan's diverse population, the chronic and often debilitating autoimmune disease lupus affects Hispanic and Asian women more frequently than white women, according to a new study led by investigators at NYU School of Medicine.

11 Sep 2017

Researchers find striking racial, ethnic disparities in incidence and prevalence of lupus

Two new papers reveal striking racial and ethnic disparities in the incidence and prevalence of lupus, a systemic autoimmune disease that can affect virtually any organ system.

11 Sep 2017

Scientists uncover new genetic markers that predispose individuals to lupus

Scientists from an international consortium have identified a large number of new genetic markers that predispose individuals to lupus.

18 Jul 2017

ACR, AAHKS release new guideline to reduce joint infections after total hip and knee replacements

According to a new guideline released by the American College of Rheumatology and American Association of Hip and Knee Surgeons, the risk of joint infection resulting from total hip and knee replacements can be reduced with careful management of anti-rheumatic medications during the perioperative process.

16 Jun 2017

Scientists uncover mechanism that directly links inflammation to mental illness

Up to 75 percent of patients with systemic lupus erythematosus -- an incurable autoimmune disease commonly known as lupus -- experience neuropsychiatric symptoms.

14 Jun 2017

Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Researchers in France have developed a new method that will allow doctors to detect minute amounts of a protein called interferon-a in patient samples.

18 Apr 2017

Women have statistically lower incidence of severe psoriasis compared to men, study reveals

The fact that men are overrepresented in psoriasis registers and consume more psoriasis care have long led researchers to believe that the common skin disease disproportionally affects men.

24 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Using red blood cells modified to carry disease-specific antigens, scientists in the laboratories of Hidde Ploegh and Harvey Lodish have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.

7 Mar 2017

Systemic Lupus Erythematosus News and Research

Scientists discover the genetic cause of immune disorders

Scientists discover how gene mutation affects T cell function to promote immune disorders

Patients with rheumatologic disease can safely receive life-saving cancer immunotherapy

Study finds link between lupus and elevated risk of dementia

Study shows lupus support line as valuable resource to help patients cope with disease

Obesity linked to worse patient-reported outcomes in women with lupus

Dietary intake of omega-3 and omega-6 fatty acids may affect outcomes in lupus patients

Vitamin D insufficiency associated with higher rates of renal disease in lupus patients

UH professors developing new home test kit for kidney nephritis

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

New guideline on care of adults with lupus published

Study: Lupus affects Hispanic, Asian women in Manhattan more frequently than white women

Researchers find striking racial, ethnic disparities in incidence and prevalence of lupus

Scientists uncover new genetic markers that predispose individuals to lupus

ACR, AAHKS release new guideline to reduce joint infections after total hip and knee replacements

Scientists uncover mechanism that directly links inflammation to mental illness

Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Women have statistically lower incidence of severe psoriasis compared to men, study reveals

New drug-like compound shows potential to treat symptoms of lupus

Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News