Systemic Lupus Erythematosus News and Research

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Systemic lupus erythematosus (SLE) is the form of the disease that most people are referring to when they say "lupus." The word "systemic" means the disease can affect many parts of the body. The symptoms of SLE may be mild or serious. Although SLE usually first affects people between the ages of 15 and 45 years, it can occur in childhood or later in life as well.
Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Patients with autoimmune diseases at greater risk of complications after heart attack

Patients with autoimmune diseases at greater risk of complications after heart attack

New data analysis approach could help uncover the genetic basis of many diseases

New data analysis approach could help uncover the genetic basis of many diseases

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

The origins, breadth, and resolution of autoreactivity in severe COVID-19

The origins, breadth, and resolution of autoreactivity in severe COVID-19

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

Video game intervention improves attention and executive functioning in patients with lupus

Video game intervention improves attention and executive functioning in patients with lupus

The global succinylation and protein abundance in SARS-CoV-2–infected cells

The global succinylation and protein abundance in SARS-CoV-2–infected cells

Booster dose of SARS-CoV-2 vaccine benefits lupus patients

Booster dose of SARS-CoV-2 vaccine benefits lupus patients

Novel molecular pathway may explain how stress affects neuropsychiatric lupus

Novel molecular pathway may explain how stress affects neuropsychiatric lupus

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

UH expert in lupus reports two new discoveries

UH expert in lupus reports two new discoveries

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Elevated and sustained autoantibodies following COVID-19

Elevated and sustained autoantibodies following COVID-19

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus