TDP 43 News and Research

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Scientists determine structure of the molecule associated with ALS for the first time

Scientists determine structure of the molecule associated with ALS for the first time

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Scientists identify new compound that reverses ALS neuron damage

Scientists identify new compound that reverses ALS neuron damage

Researchers identify link between ALS and accumulation of DNA-RNA hybrids in the genome

Researchers identify link between ALS and accumulation of DNA-RNA hybrids in the genome

Study reveals new biomarker for amyotrophic lateral sclerosis

Study reveals new biomarker for amyotrophic lateral sclerosis

New technique can detect TDP-43 protein in patients with ALS and frontotemporal dementia

New technique can detect TDP-43 protein in patients with ALS and frontotemporal dementia

ALS and FTLD result from reduced transportation of messenger RNA

ALS and FTLD result from reduced transportation of messenger RNA

Scientists unlock crucial molecular details regarding tau's activity

Scientists unlock crucial molecular details regarding tau's activity

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

New criteria to differentiate between frontotemporal dementia and LATE disease

New criteria to differentiate between frontotemporal dementia and LATE disease

Study indicates a potential link between Alzheimer's and common brain disorder

Study indicates a potential link between Alzheimer's and common brain disorder

Study highlights a complex and under-recognized form of dementia

Study highlights a complex and under-recognized form of dementia

Link between ALS and Alzheimer's disease can help advance the search for new therapies

Link between ALS and Alzheimer's disease can help advance the search for new therapies

Blue light illuminates key ALS pathologies in zebrafish

Blue light illuminates key ALS pathologies in zebrafish

Supplementing diet with amino acid delays signs of ALS in animal study

Supplementing diet with amino acid delays signs of ALS in animal study

Unexpected findings could lead to new therapeutic intervention for ALS

Unexpected findings could lead to new therapeutic intervention for ALS