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Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Study investigates the impact of helminth infection on COVID-19 mRNA vaccine efficacy, revealing that while antibody responses remain largely unaffected, T-cell responses are significantly impaired, particularly against Omicron variants.

17 Jan 2024

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Could spinach extract accelerate wound healing in those with diabetes?

A recent Scientific Reports study evaluated the effect of spinach extract on wound healing in diabetic rats.

13 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

The immunomodulatory and antiviral function of vitamin D

Vitamin D's immunomodulatory and antiviral function.

4 Aug 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Researchers explored the impact of biological interventions in reducing cardiovascular risk among psoriasis patients.

6 Feb 2023

Correlating circulating adipokine levels with COVID-19 severity

Researchers determine whether plasma adipokine levels were associated with COVID-19-related systemic inflammation and severity.

14 Dec 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

Do SSRIs lower the risk of long COVID?

Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).

15 Nov 2022

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

In a new study, researchers compared serum cytokine expression among healthy individuals and those with PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)].

10 Oct 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

UK study finds an increase in cardiovascular diseases and diabetes up to 12 months after COVID-19

Researchers determined whether the incidence of new diabetes mellitus (DM) and cardiovascular diseases (CVDs) increases in a year among those recovering from COVID-19.

21 Jul 2022

TNFα News and Research

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study reveals intestinal helminth infection diminishes T cell response to COVID-19 mRNA vaccine

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Could spinach extract accelerate wound healing in those with diabetes?

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The immunomodulatory and antiviral function of vitamin D

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

What is the role of B cells in breast cancer pathology?

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Correlating circulating adipokine levels with COVID-19 severity

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Do SSRIs lower the risk of long COVID?

Reduced expression of interleukin 8 and interferon-gamma cytokines identified in long COVID

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

What is the association between body fat and COVID-19?

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A good night's sleep promotes immunity

UK study finds an increase in cardiovascular diseases and diabetes up to 12 months after COVID-19

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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