TSC1 News and Research

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Findings could lead to potential new therapies for tumor-causing disorder

Findings could lead to potential new therapies for tumor-causing disorder

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

TSC1 status may predict response to Hsp90 inhibitors in bladder cancer patients

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

Drug treatment at a young age could help reverse autism-like behavior in tuberous sclerosis

Scientists develop new drug for treating skin lesions in rare intractable disease

Scientists develop new drug for treating skin lesions in rare intractable disease

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Study links heart failure biomarker to tumors observed in rare genetic diseases

Study links heart failure biomarker to tumors observed in rare genetic diseases

Study suggests new ways to treat neurological symptoms linked to tuberous sclerosis complex

Study suggests new ways to treat neurological symptoms linked to tuberous sclerosis complex

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Two candidate mTOR therapy biomarkers identified in RCC

Two candidate mTOR therapy biomarkers identified in RCC

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Study demonstrates effectiveness of everolimus for TSC patients

Study demonstrates effectiveness of everolimus for TSC patients

Deleting a single gene results in autism-like behavior

Deleting a single gene results in autism-like behavior

FDA approves Novartis’ Afinitor for treatment of renal angiomyolipomas and TSC

FDA approves Novartis’ Afinitor for treatment of renal angiomyolipomas and TSC

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

Scientists identify key immune system regulator in white blood cells

Scientists identify key immune system regulator in white blood cells

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

Novartis Afinitor Phase III trial on tuberous sclerosis meets primary endpoint

CINJ: Common genetic variation impacts diagnosis of breast cancer in postmenopausal women

CINJ: Common genetic variation impacts diagnosis of breast cancer in postmenopausal women

Autism spectrum disorders result from miswiring of connections in developing brain

Autism spectrum disorders result from miswiring of connections in developing brain

TSC proteins regulate Notch activity

TSC proteins regulate Notch activity

Prenatal molecular diagnosis for tuberous sclerosis complex

Prenatal molecular diagnosis for tuberous sclerosis complex