The Microbiome Project News and Research

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The human microbiome refers to the entire community of microorganisms that live on or in the human body. More specifically, it refers to all of the genes in these microbes, which include bacteria, fungi, protozoa, and viruses.

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

MicroBiome Therapeutics LLC, a biotechnology company developing pharmaceutical and medical food products that shift the human microbiome in specific ways for improved health, today reported publication of a case report suggesting a potentially important new application for its lead product, NM504. NM504 is in clinical development to promote healthy blood glucose levels and metabolic fitness in prediabetic and diabetic populations.

11 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Affinium Pharmaceuticals announced today that it has initiated dosing in a Phase 1 intravenous clinical trial of its new antibiotic prodrug, AFN-1720. AFN-1720 is the prodrug of the active drug, AFN-1252.

5 Sep 2013

JCVI Receives $1.25M For Healthy Aging Study

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29 Aug 2013

JCVI Receives $1.25M For Healthy Aging Study

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28 Aug 2013

Review Article examines FMT methodology as effective treatment for C. difficile infection

Fecal microbiota transplantation has emerged as a highly effective treatment for recurrent Clostridium difficile infection, with very early experience suggesting that it may also play a role in treating other gastrointestinal and non-GI diseases.

23 Aug 2013

Caltech biologists identify mechanism by which beneficial bacteria reside, thrive in gastrointestinal tract

The human body is full of tiny microorganisms-hundreds to thousands of species of bacteria collectively called the microbiome, which are believed to contribute to a healthy existence. The gastrointestinal (GI) tract-and the colon in particular-is home to the largest concentration and highest diversity of bacterial species.

20 Aug 2013

Probiotic supplements have no effect on the incidence of diarrhoea in elderly patients

Probiotic supplements given to elderly patients on antibiotics appear to have no effect on the incidence of diarrhoea, a common and sometimes life-threatening side effect of using antibiotics for many elderly patients, according to a new study published in The Lancet.

9 Aug 2013

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Roche announced today the global launch of a new software update that significantly extends the range of amplicon lengths available for targeted next-generation sequencing studies on the 454 GS FLX+ System.

7 Aug 2013

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

Call it therapeutic poop, if you will, but the best hope yet for an effective treatment of childhood infections with the drug-resistant bacterium C. difficile may come straight from the gut, according to recent research.

30 Jul 2013

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Rebiotix Inc. announced today that the U.S. Food and Drug Administration has approved the company's Investigational New Drug application to begin the Phase 2 clinical study of RBX2660 for the treatment of recurrent Clostridium difficile infection.

30 Jul 2013

Study shows environmental conditions have stronger influence on human microbiome

Environmental conditions have a much stronger influence on the mix of microbes living in various parts of your body than does competition between species. Instead of excluding each other, microbes that fiercely compete for similar resources are more likely to cohabit the same individual.

17 Jul 2013

Specific types of intestinal bacteria are major contributors to lymphoma

Researchers from UCLA's Jonsson Comprehensive Cancer Center (JCCC) have discovered that specific types of bacteria that live in the gut are major contributors to lymphoma, a cancer of the white blood cells that are part of the human immune system.

16 Jul 2013

Oral probiotic supplement increases vitamin D levels in blood, says study

A study published in the Journal of Clinical Endocrinology & Metabolism is the first report of an oral probiotic supplement significantly increasing circulating vitamin D levels in the blood.

20 Jun 2013

New technique offers potential to screen patients for viruses

In research published in Biochemical and Biophysical Research Communications, Saint Louis University researchers describe a technology that can detect new, previously unknown viruses. The technique offers the potential to screen patients for viruses even when doctors have not identified a particular virus as the likely source of an infection.

18 Jun 2013

Drug targeting of phages could offer a potential new path to mitigate antibiotic resistance

Bacteria in the gut that are under attack by antibiotics have allies no one had anticipated, a team of Wyss Institute scientists has found. Gut viruses that usually commandeer the bacteria, it turns out, enable them to survive the antibiotic onslaught, most likely by handing them genes that help them withstand the drug.

11 Jun 2013

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Linneah sat at a desk at the Center for Sexual Medicine at Sheppard Pratt in the suburbs of Baltimore and filled out a questionnaire. She read briskly, making swift checks beside her selected answers, and when she was finished, she handed the pages across the desk to Martina Miller, who gave her a round of pills.

24 May 2013

The Microbiome Project News and Research

Further Reading

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

JCVI Receives $1.25M For Healthy Aging Study

JCVI Receives $1.25M For Healthy Aging Study

Review Article examines FMT methodology as effective treatment for C. difficile infection

Caltech biologists identify mechanism by which beneficial bacteria reside, thrive in gastrointestinal tract

Probiotic supplements have no effect on the incidence of diarrhoea in elderly patients

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Study shows environmental conditions have stronger influence on human microbiome

Specific types of intestinal bacteria are major contributors to lymphoma

Oral probiotic supplement increases vitamin D levels in blood, says study

New technique offers potential to screen patients for viruses

Drug targeting of phages could offer a potential new path to mitigate antibiotic resistance

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Research highlights benefits of vitamin D, diet changes in patients with Crohn's disease

AGA researchers to present exciting data on GI disorders at DDW 2013

AGA announces new grant to study relationship between gut microbiota, digestive disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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