The Microbiome Project News and Research

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The human microbiome refers to the entire community of microorganisms that live on or in the human body. More specifically, it refers to all of the genes in these microbes, which include bacteria, fungi, protozoa, and viruses.

New evidence may explain how gut microorganisms affect human physiology

Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies.

30 Dec 2016

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Further to a successful follow-up audit, IBBL (Integrated BioBank of Luxembourg) becomes the first biobank worldwide to be accredited for the next-generation 16S rRNA gene sequencing, a cutting-edge method that takes forward research into the human microbiome.

23 Dec 2016

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge.

21 Dec 2016

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered.

19 Dec 2016

Researchers use worms as model system to study how gut microbiome influences disease

The billions of microorganisms living within the human digestive tract appear to play a significant role in health and disease, notably metabolic syndrome, autoimmune disorders and diabetes - but how these organisms do so is not well understood.

17 Dec 2016

Review highlights link between intestinal microbiota and colorectal cancer development

Recent evidence from animal models suggests a role for specific types of intestinal bacteria in the development of colorectal cancer (CRC).

9 Dec 2016

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota (bacteria in the uterine cavity) play an important role in determining whether women are able to get pregnant via in vitro fertilization (IVF), according to a new study published in the American Journal of Obstetrics and Gynecology.

6 Dec 2016

Gut microbes may play important role in exacerbated post-dieting weight gain

Following a successful diet, many people are dismayed to find their weight rebounding - an all-too-common phenomenon termed "recurrent" or "yo-yo" obesity.

5 Dec 2016

New Baylor study aims to investigate antibiotic effect in children with ASD

Over the Thanksgiving holiday in 2012, John Rodakis, a father of a child with autism, observed his son's condition dramatically improve while taking a common antibiotic.

1 Dec 2016

Scientists create comprehensive computational metabolic models for different gut microbes

Hundreds of different bacterial species live in the human gut, helping us to digest our food. The metabolic processes of these bacteria are not only tremendously important to our health -- they are also tremendously complex.

29 Nov 2016

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology.

29 Nov 2016

TUM scientists explore link between gastrointestinal microbiota and dietary fats

Gut bacteria play a little-understood role in the body’s energy balance, which is influenced by diet. However, the crucial nutritional components are unknown. A team at the Technical University of Munich was able to demonstrate for the very first time that mice without gastrointestinal microbiota grow obese when fed with dietary fat from plant sources, but not from animal sources.

25 Nov 2016

New research provides insights into how gut microbes drive host gene expression

In our guts, and in the guts of all animals, resides a robust ecosystem of microbes known as the microbiome. Consisting of trillions of organisms — bacteria, fungi and viruses — the microbiome is essential for host health, providing important services ranging from nutrient processing to immune system development and maintenance.

23 Nov 2016

New research shows impact of fiber deprivation on mouse gut

It sounds like the plot of a 1950s science fiction movie: normal, helpful bacteria that begin to eat their host from within, because they don't get what they want.

17 Nov 2016

Enterome, Bristol-Myers Squibb enter into Immuno-Oncology collaboration to identify new microbiome-derived biomarkers for cancer

Bristol-Myers Squibb (NYSE: BMY) and Enterome SA (Enterome), a pioneer in the development of pharmaceuticals and diagnostics based on the gut microbiome, announced that they have entered into an Immuno-Oncology focused collaboration agreement for the discovery and development of microbiome-derived biomarkers, drug targets and bioactive molecules to be developed as potential companion diagnostics and therapeutics for cancer.

16 Nov 2016

Gut microbiota may play important role in influencing onset of blinding wet AMD

Age-related Macular Degeneration (AMD) is the leading cause of irreversible blindness in the industrialized world, affecting over 10 million individuals in North America.

15 Nov 2016

Prenatal exposure to mother's stress causes microbial changes that persist into adulthood

Prenatal exposure to a mother's stress contributes to anxiety and cognitive problems that persist into adulthood, a phenomenon that could be explained by lasting - and potentially damaging - changes in the microbiome, according to new research in mice.

15 Nov 2016

Identifying foods that trigger IBS: an interview with Dr Bill Chey

IBS is a common medical condition which is diagnosed in the presence of characteristic gastrointestinal symptoms including recurring bouts of abdominal pain and diarrhea and/or constipation. IBS patients also commonly report bloating and abdominal distension or swelling.

15 Nov 2016

Researchers lay foundation for improved TB treatment by targeting new enzyme

Researchers at Johns Hopkins report they have laid the foundation to develop novel antibiotics that work against incurable, antibiotic-resistant bacteria like tuberculosis by targeting an enzyme essential to the production and integrity of bacterial cell walls.

10 Nov 2016

Researchers shed light on how success of gut microbiome treatments may depend on genetics

Our gut microbiomes--the bacteria that live in our digestive tract--play major roles in our health. Scientists around the world are studying therapies that manipulate the microbiome, including probiotics (such as live bacterial cultures in yogurt), prebiotics (edible fibers meant to promote beneficial bacteria), antibiotics and transplants of microbes from healthy people.

7 Nov 2016

The Microbiome Project News and Research

Further Reading

New evidence may explain how gut microorganisms affect human physiology

IBBL becomes first biobank to be accredited for next-generation microbial sequencing

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Researchers use worms as model system to study how gut microbiome influences disease

Review highlights link between intestinal microbiota and colorectal cancer development

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Gut microbes may play important role in exacerbated post-dieting weight gain

New Baylor study aims to investigate antibiotic effect in children with ASD

Scientists create comprehensive computational metabolic models for different gut microbes

Early life history and genetics may play crucial role in shaping gut microbiome

TUM scientists explore link between gastrointestinal microbiota and dietary fats

New research provides insights into how gut microbes drive host gene expression

New research shows impact of fiber deprivation on mouse gut

Enterome, Bristol-Myers Squibb enter into Immuno-Oncology collaboration to identify new microbiome-derived biomarkers for cancer

Gut microbiota may play important role in influencing onset of blinding wet AMD

Prenatal exposure to mother's stress causes microbial changes that persist into adulthood

Identifying foods that trigger IBS: an interview with Dr Bill Chey

Researchers lay foundation for improved TB treatment by targeting new enzyme

Researchers shed light on how success of gut microbiome treatments may depend on genetics

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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