Therapeutics News and Research

RSS

‘They see a cash cow’: Corporations could consume $50 billion of opioid settlements

The marketing pitches are bold and arriving fast: Invest opioid settlement dollars in a lasso-like device to help police detain people without Tasers or pepper spray.

18 Dec 2023

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria -; albumin in urine, a sign of kidney damage -; for 50% of participants.

15 Dec 2023

$9M awarded to study HIV and substance use at intersection of vulnerable populations

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) received an annual award for $3 million funded by the NIH Office of AIDS Research.

15 Dec 2023

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells.

15 Dec 2023

Hemoglobin-like protein plays an important role in the development of the heart, study finds

In a landmark study led by the University of Maryland School of Medicine, researchers discovered for the first time that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart.

15 Dec 2023

RNA-seq analysis reveals key factors in intervertebral disc degeneration

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD).

15 Dec 2023

New AI framework can rapidly identify new use cases for existing therapeutics

Scientists at Klick Applied Sciences have created an artificial intelligence framework that can rapidly identify new use cases for existing therapeutics, according to findings presented Friday at the NeurIPS conference that could greatly improve the drug repurposing process and transform the pharmaceutical industry.

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Mount Sinai wins $1.3 million NIH award to expand the New York City Virus Hunters program

The Icahn School of Medicine at Mount Sinai has received more than $1.3 million from the National Institute of General Medical Sciences of the National Institutes of Health (NIH) to expand the New York City Virus Hunters program.

14 Dec 2023

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Genome-wide association studies (GWAS) on patient blood samples are useful for identifying the genetic basis of blood cell traits and their links to common diseases.

14 Dec 2023

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome" -; the 98 percent of our DNA that has largely unknown biological function.

14 Dec 2023

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.

14 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

UK drug regulators failing to protect patients from harmful weight loss

UK organizations responsible for protecting the public from prescription-only drug adverts are putting patients at risk from the harms of weight loss drugs by not enforcing the law, reveals an investigation published by The BMJ today.

14 Dec 2023

Scientists unlock secret to repairing malnourished children's guts

A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children's underdeveloped gut microbiomes was superior to a widely used standard therapeutic food.

13 Dec 2023

Gavi commits more than US$1.8 billion to support vaccine production in Africa

Gavi, the vaccine alliance, says it has committed more than US$1.8 billion to support vaccine production in Africa, a move that could bolster the continent’s efforts to address historical dependence on imported vaccines and establish its own robust biotechnology sector.

12 Dec 2023

UMSOM receives $29 million research award to improve health outcomes in people who inject opioid drugs

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that the school will receive a $29 million research award over four years from the National Institutes of Health to lead a multicenter trial that aims to improve health outcomes in people who inject opioid drugs and are hospitalized with infectious complications of their drug use.

11 Dec 2023

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

In a study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, patients recently diagnosed with a common and aggressive form of acute myeloid leukemia reported having improved quality of life when a newly approved drug was part of the treatment plan.

11 Dec 2023

Research uncovers potential treatment target for rare, genetic type of epilepsy

Researchers at the Francis Crick Institute, UCL and MSD have identified a potential treatment target for a genetic type of epilepsy.

11 Dec 2023

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who are likely to experience a disease recurrence -; potentially letting some patients who are predicted to have favorable outcomes forgo lengthy treatment.

11 Dec 2023

Therapeutics News and Research

‘They see a cash cow’: Corporations could consume $50 billion of opioid settlements

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

$9M awarded to study HIV and substance use at intersection of vulnerable populations

Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

Hemoglobin-like protein plays an important role in the development of the heart, study finds

RNA-seq analysis reveals key factors in intervertebral disc degeneration

New AI framework can rapidly identify new use cases for existing therapeutics

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Mount Sinai wins $1.3 million NIH award to expand the New York City Virus Hunters program

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Unlocking the secrets of our "dark genome": Scientists crack the code of LINE-1

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

UK drug regulators failing to protect patients from harmful weight loss

Scientists unlock secret to repairing malnourished children's guts

Gavi commits more than US$1.8 billion to support vaccine production in Africa

UMSOM receives $29 million research award to improve health outcomes in people who inject opioid drugs

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

Research uncovers potential treatment target for rare, genetic type of epilepsy

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News