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New imaging technique provides a much closer look at fibril assemblies

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably associated with Alzheimer's disease.

26 Apr 2024

Study suggests a common brain network exists between heart rate deceleration and depression

A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

26 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Surgeons at NYU Langone Health performed the first combined mechanical heart pump and gene-edited pig kidney transplant surgery.

24 Apr 2024

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

AI models fall short in medical coding accuracy

State-of-the-art artificial intelligence systems known as large language models (LLMs) are poor medical coders, according to researchers at the Icahn School of Medicine at Mount Sinai.

22 Apr 2024

Insightful review explores alcohol-related liver cancer pathogenesis

While heavy drinking is a well-established risk factor for liver cancer, the specific mechanisms by which alcohol contributes to A-HCC remain unclear.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

UCSF study identifies cells responsible for cough reflex

When a mouthful of water goes down the wrong pipe – heading toward a healthy person’s lungs instead of their gut – they start coughing uncontrollably.

18 Apr 2024

New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

Therapeutics News and Research

New imaging technique provides a much closer look at fibril assemblies

Study suggests a common brain network exists between heart rate deceleration and depression

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

NYU Langone surgeons perform first combined mechanical heart pump and gene-edited pig kidney transplant surgery

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Analysis finds significant variations in national COVID-19 treatment recommendations

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

CN Bio raises $21 million USD in first close of Series B investment round

AI models fall short in medical coding accuracy

Insightful review explores alcohol-related liver cancer pathogenesis

Top pharmaceutical company evaluates Optimer for precision liver medicine

UCSF study identifies cells responsible for cough reflex

New urine-based test improves identification of high-grade prostate cancer

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

Salk scientists explain how CBN protects the brain against aging and neurodegeneration

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Managing diabetes with probiotics and synbiotics

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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