Thrombus News and Research

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A blood clot or thrombus, is the final product of the blood coagulation step in hemostasis. It is achieved via the aggregation of platelets that form a platelet plug, and the activation of the humoral coagulation system (i.e. clotting factors).

Review of haemodynamics in stent development shows spiral flow may be key to improving peripheral arterial stent performance

Vascular Flow Technologies, the medical device company using proprietary Spiral Laminar Flow (SLF™) technology to replicate natural blood flow for enhanced patient outcomes, today announces that 'Haemodynamics and Flow Modification Stents for Peripheral Arterial Disease: A Review’, co-authored by VFT’s non-executive Medical Director Graeme Houston, has been published in the Annals of Biomedical Engineering. The paper reviews the importance of haemodynamics in stent development as a method of improving patency and longevity of the stent.

4 Nov 2015

New tool may help identify high risk atherosclerotic plaques

Researchers have developed and validated a new tool to help identify unstable or high risk atherosclerotic plaques--inflamed fatty deposits in the artery wall and a main contributor to cardiovascular disease (CVD). This breakthrough may lead to better identifying which plaques are considered at the highest risk for rupturing and causing a heart attack or stroke.

14 Oct 2015

New approach helps create virtual models for treating abdominal aortic aneurysms

Virtual models can be created in the angiography room thanks to an approach developed by researchers at the University of Montreal Hospital Research Centre and the university's departments of radiology, radiation oncology, and nuclear medicine. The latest advances were presented by Dr. Gilles Soulez at the Cardiovascular and Interventional Radiology Society of Europe conference on September 27, 2015.

8 Oct 2015

Acute Cardiovascular Care 2015 to be held in Vienna from 17 to 19 October

Acute Cardiovascular Care 2015 will highlight innovations and controversies in the field, guaranteeing great stories on topics relevant to the press.

18 Sep 2015

SLU scientist receives grant to solve blood-clotting mysteries

Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a "linker" region that may be the key to developing better life-saving drugs.

1 Sep 2015

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

Retrieval of larger thrombi during intra arterial treatment (IAT) is associated with improved neurological recovery after acute ischaemic stroke, according to a sub study of the MR CLEAN trial presented at ESC Congress today by Dr Anouchska Autar, PhD candidate at the Erasmus Medical Centre in Rotterdam, the Netherlands.

1 Sep 2015

PRESTIGE study suggests novel target to prevent stent thrombosis

Recruitment of leukocytes is a hallmark of stent thrombosis, according to results from the PRESTIGE study presented today at ESC Congress and published in European Heart Journal. The findings suggest that immune cell mediated thrombotic processes may be a realistic target for novel therapies to prevent stent thrombosis.

1 Sep 2015

Symic receives $1.5M NIH Phase II SBIR grant to develop AVF therapeutic candidate

Platform therapeutic company Symic Biomedical, Inc. announced today that it has received a $1.5M Phase II SBIR grant from the National Institutes of Health to further develop its therapeutic agent to reduce arteriovenous fistula (AVF) failures, a significant unmet clinical need in end stage renal disease (ESRD) patients undergoing hemodialysis.

27 Aug 2015

Neovasc's second quarter revenues drop 18%

Neovasc Inc. today announced financial results for the quarter ended June 30, 2015.

6 Aug 2015

Surgeons describe positive outcomes in kidney cancer patients treated with robotic IVC thrombectomy

Surgery is required when cancer of the kidney causes a Level III thrombus, or clot, to develop in the major vein leading back to the heart. Traditionally this complicated procedure, inferior vena cava (IVC) thrombectomy, is performed using a large open incision, primarily because the vein is often difficult to reach.

30 Jul 2015

Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

The National Institute for Health and Care Excellence has recommended a new treatment to help patients suffering from blood clots in the legs and lungs.

13 Jul 2015

Using nanocarriers and microbubbles in drug delivery for treating thrombotic disease

Future Science Group today announced the publication of a new article in Future Science OA, covering the use of nanocarriers and microbubbles in drug delivery for thrombotic disease.

7 Jul 2015

Inari Medical closes $12.4 million Series B venture capital financing

Inari Medical, Inc. announced today that it has closed a $12.4 million Series B venture capital financing. The financing was led by members of the board of directors and returning investors Versant Ventures and US Venture Partners. The round also included participation by several medical device industry veterans.

30 Jun 2015

LMU cardiologists study new approach to inhibit atherosclerotic plaque-induced platelet activation

Blood clots often form when lipid-rich plaques on the inner surface of arteries rupture and platelets aggregate at the site of injury. Cardiologists from Ludwig-Maximilians-Universitaet in Munich have now compared the effects of two new platelet aggregation inhibitors.

4 Jun 2015

Lung cancer surgery patients at higher risk of developing venous thromboembolism

New evidence suggests that lung cancer surgery patients are at higher risk of developing venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), than previously thought, with elevated risks of complications or death. When thromboemboli occur, they may be asymptomatic or attributed to post-surgical pain or complications, and may reflect both the lung cancer itself as well as compromised lung function after surgery.

29 Apr 2015

Two case studies provide potential new avenue for treatment of kidney cancer

UT Southwestern Medical Center Kidney Cancer Program investigators have published what is believed to be the first reported successful use of stereotactic body radiation therapy for an often deadly complication of kidney cancer.

8 Apr 2015

MHIF investigator performs first atrial fibrillation ablation in U.S. using SMARTTOUCH SF catheter

Dr. Daniel Melby, an investigator at the Minneapolis Heart Institute Foundation, performed the first atrial fibrillation ablation in the U.S. using Biosense Webster's new THERMOCOOL SMARTTOUCH SF contact force sensing catheter as part of an FDA regulated safety trial (SMART-SF).

1 Apr 2015

CT measures can refine PAH prognosis

Structural features identifiable on computed tomography pulmonary angiography can provide prognostic information for patients with pulmonary arterial hypertension, say UK researchers.

16 Jan 2015

Thrombus aspiration for acute myocardial infarction does not reduce mortality

Thrombus aspiration for acute myocardial infarction (AMI) does not reduce mortality or other clinical endpoints long term, according to the awaited one-year follow-up results from the Thrombus Aspiration in ST- Elevation myocardial infarction in Scandinavia (TASTE) trial.

2 Sep 2014

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes.

3 Jun 2014

Thrombus News and Research

Further Reading

Review of haemodynamics in stent development shows spiral flow may be key to improving peripheral arterial stent performance

New tool may help identify high risk atherosclerotic plaques

New approach helps create virtual models for treating abdominal aortic aneurysms

Acute Cardiovascular Care 2015 to be held in Vienna from 17 to 19 October

SLU scientist receives grant to solve blood-clotting mysteries

Study: Retrieval of larger thrombi during IAT linked to improved neurological recovery after acute ischaemic stroke

PRESTIGE study suggests novel target to prevent stent thrombosis

Symic receives $1.5M NIH Phase II SBIR grant to develop AVF therapeutic candidate

Neovasc's second quarter revenues drop 18%

Surgeons describe positive outcomes in kidney cancer patients treated with robotic IVC thrombectomy

Lixiana (edoxaban) recommended for treating, preventing recurrent DVT and PE in adults

Using nanocarriers and microbubbles in drug delivery for treating thrombotic disease

Inari Medical closes $12.4 million Series B venture capital financing

LMU cardiologists study new approach to inhibit atherosclerotic plaque-induced platelet activation

Lung cancer surgery patients at higher risk of developing venous thromboembolism

Two case studies provide potential new avenue for treatment of kidney cancer

MHIF investigator performs first atrial fibrillation ablation in U.S. using SMARTTOUCH SF catheter

CT measures can refine PAH prognosis

Thrombus aspiration for acute myocardial infarction does not reduce mortality

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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