Thymus News and Research

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Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery-; successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

Mayo Clinic study: Increasing physical activity decreases risk of death from lymphoma

An observational study by researchers at Mayo Clinic has found that increasing physical activity not only decreased the risk of death from all causes but also decreased the risk of death specifically from lymphoma.

13 Dec 2017

FDA grants accelerated approval to new treatment for mantle cell lymphoma

The U.S. Food and Drug Administration today granted accelerated approval to Calquence (acalabrutinib) for the treatment of adults with mantle cell lymphoma who have received at least one prior therapy.

1 Nov 2017

Study provides early glimpse of gut's microbial landscape

A collaborative effort by a team of researchers from three institutions including the Marine Biological Laboratory in Woods Hole, the Forsyth Institute in Cambridge and Washington University in St. Louis provided an early glimpse of how microbial communities in the gut - known collectively as the gut microbiome - are spatially organized, uncovering a surprising degree of mixing among different bacterial members.

11 Oct 2017

Neurohistology: how whole slide scanning impacts workflow

MultiBrain technology can accelerate the R&D preclinical and safety assessment processes many fold and perform them less expensively.

From Huron Digital Pathology 21 Sep 2017

Research deepens understanding of interconnection between nervous and immune system

A newly-discovered reflex arc mediates a process which leads to a disruption in the hormones secreted by the adrenal glands which, in turn, results in an increased susceptibility to bacterial infections.

19 Sep 2017

FDA grants accelerated approval to new drug for treating relapsed follicular lymphoma

The U.S. Food and Drug Administration today granted accelerated approval to Aliqopa (copanlisib) for the treatment of adults with relapsed follicular lymphoma who have received at least two prior treatments known as systemic therapies.

14 Sep 2017

Researchers identify new in-utero treatment to reverse cleft palate in mouse models

Researchers at University of Utah Health clarified a molecular pathway responsible for the formation of cleft palate and identified a new treatment to reverse this defect in mouse pups in-utero.

13 Sep 2017

ActuRx and Insillico Medicine collaborate to prevent, treat age-related illnesses

Can big data and financial engineering cure Cancer, Alzheimer's, and other age-related illnesses? ActuRx and Insillico Medicine think so.

5 Jul 2017

Finnish researchers find accumulation of gene mutations in some patients with rheumatoid arthritis

Gene mutations accumulating in cells are typical of the development of cancer. Finnish researchers found that a similar accumulation of mutations occurs also in some patients with rheumatoid arthritis.

21 Jun 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Study sheds light on role of Armc5 protein in foetal development and T-cell immune responses

Genetic mutations of the Armc5 gene disrupt foetal development and compromise the immune response.

8 Feb 2017

Johns Hopkins scientists reveal extra centrosomes can promote tumor formation in mice

When a cell is dividing, two identical structures, called centrosomes, move to opposite sides of the cell to help separate its chromosomes into the new cells.

28 Jan 2017

Scientists report new molecular mechanism that could be cause of autoimmune diseases

Scientists at the Immunology Frontier Research Center (IFReC), Osaka University, Japan, report a new molecular mechanism that could explain the cause of some autoimmune diseases.

27 Dec 2016

Blocking protein that initiates immune response against viral infections may help combat HIV

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV.

23 Dec 2016

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response.

17 Dec 2016

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016