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LegoChem Biosciences and Iksuda Therapeutics expand License Agreement for development of antibody-drug conjugates

Iksuda Therapeutics today announced that it has expanded its research collaboration and License Agreement with LegoChem Biosciences, Inc.

From Iksuda Therapeutics 22 Jun 2021

Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Scientists at Duke-NUS Medical School and National Heart Centre Singapore, in collaboration with colleagues in Singapore and the UK, have shown that the human form of the signaling protein interleukin 11 (IL-11) has a damaging effect on human liver cells--overturning a prior hypothesis that it could help livers damaged by paracetamol poisoning.

18 Jun 2021

Study paves the way for development of new therapeutics for C. difficile infection

A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.

18 Jun 2021

P-glycoprotein shows ability to remove a toxin associated with Alzheimer's from the brain

\A team of SMU biological scientists has confirmed that P-glycoprotein (P-gp) has the ability to remove a toxin from the brain that is associated with Alzheimer's disease.

16 Jun 2021

Restoration can improve mining contamination, indicates study

Mining involves moving a lot of rock, so some mess is expected. However, mining operations can continue to affect ecosystems long after activity has ended. Heavy metals and corrosive substances leach into the environment, preventing wildlife and vegetation from returning to the area.

9 Jun 2021

Cows can pass on hypoglycin A toxin through their milk, shows study

Cows can pass on the hypoglycin A toxin through their milk, a study by the Martin Luther University Halle-Wittenberg (MLU) and the Leibniz Institute of Plant Biochemistry (IPB) in Toxins shows. The substance can cause severe symptoms in humans and animals.

8 Jun 2021

Pseudomonas aeruginosa poses a serious threat to human health

No one knows exactly when humans and pathogenic bacteria were encountered with each other. But since then, the war began over life and survival between them. During this time, both sides of the war tried to equip themselves with all their might.

2 Jun 2021

Weaker association between brain activity and cerebrospinal fluid flow increases the likelihood of Alzheimer's disease

New imaging research shows that brain activity during sleep was less connected with cerebrospinal fluid flow in patients with Alzheimer's disease.

1 Jun 2021

Researchers develop mathematical model to prevent botulism

Food producers can use a mathematical model developed at the National Food Institute, Technical University of Denmark, to ensure their products do not cause botulism. It is the most comprehensive model of its kind.

27 May 2021

Study could lead to new antibiotics to fight bacterial infections

One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows.

21 May 2021

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology.

5 May 2021

ASPS survey reveals COVID-19's impact and patient demand for plastic surgery

The American Society of Plastic Surgeons (ASPS) - the world's largest plastic surgery organization, representing nearly 8,000 members - today released the 2020 results of the organization's annual procedure survey coupled with national consumer research reflecting trends during the COVID-19 era to help predict what 2021 will bring.

28 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

New technology shows encouraging results for treating osteosarcoma

A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells without damaging normal tissues.

13 Apr 2021