Toxin News and Research

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Scientist examines tungsten contamination in drinking water

A Kansas State University scientist is digging deep to solidify information about potential tungsten contamination in the nation's groundwater and aquifers.

28 Jan 2011

USPTO issues Notice of Allowances to Lakewood's three patent applications for treatment of HUS

Lakewood-Amedex, a leading developer of novel anti-infective pharmaceuticals, announced today that the United States Patent and Trademark Office has issued Notice of Allowances on three patent applications relating to the use of novel monoclonal antibodies for the treatment of hemolytic uremic syndrome caused by shiga toxin II secreting E.coli O157: H7 strain.

28 Jan 2011

Soligenix and CU enter definitive license agreement for novel vaccine thermostabilization technology

Soligenix, Inc., a late-stage biopharmaceutical company, today announced that it has entered into a definitive license agreement with the University of Colorado (CU) for novel technology for use in the development of subunit vaccines with long-term stability, including stability at elevated temperatures.

28 Jan 2011

FDA grants Soligenix Orphan Drug Designation to RiVax for prevention of ricin intoxication

Soligenix, Inc., a late-stage biopharmaceutical company, announced today that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation to RiVax™ for the prevention of ricin intoxication. RiVax™ is a proprietary vaccine that contains a recombinant subunit of the A chain of ricin toxin which induces ricin neutralizing antibodies in humans and animals.

20 Jan 2011

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

A complex sugar may someday become one of the most effective weapons to stop the spread of cholera, a disease that has claimed thousands of lives in Haiti since the devastating earthquake last year.

19 Jan 2011

Kenneth D. Steinsapir receives rare USPTO patent for Microdroplet BOTOX

Kenneth D. Steinsapir, M.D., has been issued a rare patent (US 7,846,457 B2) by The United States Patent and Trademark Office for the invention of a breakthrough method for administering cosmetic botulinum toxin. The patent for Microdroplet botulinum toxin, a nonsurgical cosmetic facial treatment that improves upon standard BOTOX treatments, was officially approved on December 7, 2010.

13 Jan 2011

Star Scientific develops moist snuff tobacco product with low carcinogenic levels

Star Scientific, Inc. reports that it has successfully developed a moist snuff tobacco product that has extremely low levels of carcinogens -- much lower than any snuff products currently in the marketplace. This new product has levels of tobacco-specific nitrosamines (TSNAs) -- recognized by scientists worldwide as one of the most powerful cancer-causing agents in tobacco leaf and smoke -- below 20 parts per billion (nanograms-per-gram moist weight, as used) in initial testing.

4 Jan 2011

Mercury Policy Project welcomes WHO's support for 'phasing down' amalgam

While an FDA panel re-examines risks of amalgam over the next two days, the World Health Department is expected to release a key report soon recommending that amalgam use be "phased down" globally, consistent with its earlier recommendations.

14 Dec 2010

Intercell to stop further development of Travelers' Diarrhea Vaccine Patch

Intercell AG announced today preliminary clinical results on its investigational Travelers' Diarrhea (TD) Vaccine Patch program and the decision not to pursue further the development of this vaccine candidate. The decision was made following the receipt of results of its randomized and placebo-controlled Phase III study (ELT301) with 2036 travelers from Europe to Mexico and Guatemala as well as the pilot efficacy Phase II trial (ELT209) with 723 travelers from Europe to India.

13 Dec 2010

Origin of Haiti cholera epidemic traced to South Asia

The strain of cholera currently sweeping through post-earthquake Haiti originated in South Asia, conclude scientists who did a rapid genetic analysis of bacteria collected from Haitian patients. The finding supports the notion that the cholera bacteria fueling the outbreak arrived on the island via recent visitors.

13 Dec 2010

Silencing the TLR4 gene can prevent cardiovascular disease in diabetic patients

Silencing the TLR4 gene can stop the process which may lead to cardiovascular disease in diabetic patients. Researchers demonstrated that TLR4 plays a critical role in hyperglycaemic cardiac apoptosis, and that silencing the gene using specific small interfering RNA can prevent it.

10 Dec 2010

Vibrio cholerae evolves two new mechanisms to cause similar disease

New clinical strains of cholera appear to have evolved a distinctly different mechanism to cause the same disease according to research published in the current issue of the online journal mBio-.

9 Dec 2010

Study raises questions about therapeutic use of botulinum toxin A

A new study by researchers at the Faculty of Kinesiology, University of Calgary, is raising questions about the therapeutic use of botulinum toxin A.

3 Dec 2010

Biomagnetics identifies second biomarker for tuberculosis assay

Biomagnetics Diagnostics Corp., a developer of revolutionary diagnostic systems and technology for HIV, hepatitis, tuberculosis, cholera and malaria detection, and other innovative technologies, today announced the identification of a second biomarker for development of a tuberculosis assay.

2 Dec 2010

Humanitarian benefits of rapid cholera vaccines deployment to at risk areas could be enormous

In the wake of devastating cholera outbreaks in refugee camps in earthquake-wracked Haiti, a group of leading experts from Harvard Medical School, George Washington University, and the International Vaccine Institute (IVI) have urged the United States to create an emergency stockpile of cholera vaccines for future humanitarian use.

25 Nov 2010

Ziconotide could promote suicidal tendencies in vulnerable patients: Research

24 Nov 2010

Researchers find link between acrolein and multiple sclerosis

Researchers have found evidence that an environmental pollutant may play an important role in causing multiple sclerosis and that a hypertension drug might be used to treat the disease.

24 Nov 2010

Ziconotide could promote suicidal tendencies: Study

The active agent ziconotide, the synthetic toxin of the cone snail (Conus magus), was acclaimed a safe alternative to morphine when it was introduced six years ago. Now it is increasingly suspected of causing patients to commit suicide. Researchers working under the auspices of Prof. Christoph Maier (Director of the Pain Clinic Bergmannsheil at the Ruhr University in Bochum) presume that ziconotide not only suppresses the transmission of pain stimuli, but also deteriorates the frame of mind and could simultaneously reduce anxiety and impulse control.

23 Nov 2010

Botox Cosmetics increase overall quality of life and self-esteem

Chicago Facial Plastic Surgeon, Steven H. Dayan, MD, FACS, publishes a study in the November 2010 issue of Dermatologic Surgery, a prominent Dermatology journal, demonstrating that increases in overall quality of life and self-esteem were observed in participants treated with Botulinum Toxin Type A or Botox Cosmetic. In this double-blind randomized placebo-controlled survey, Dr. Dayan and DeNova research worked with one hundred participants who were treated with either Botox Cosmetic or a saline placebo for facial wrinkles.

23 Nov 2010

Soligenix receives U.S patent for modified immunogen in RiVax vaccine

Soligenix, Inc., a late-stage biopharmaceutical company, announced today that the United States Patent and Trademark Office has granted patent #7,829,668, entitled Compositions and methods for modifying toxic effects of proteinaceous compounds.

22 Nov 2010