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New 'nanoPCR' technology can accurately diagnose COVID-19 in less than 20 minutes

A "nanoPCR" technology was developed for the point-of-care (POC) diagnosis of coronavirus disease-19 (COVID-19).

8 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

A team of researchers from various institutes in Switzerland report how saliva samples may be a strong alternative to nasal swaps in PCR-related SARS-CoV-2 testing.

8 Dec 2020

Single-cell sequencing provides new fundamental insights into 'abdominal brain'

Researchers at Karolinska Institutet have succeeded in mapping the neuron types comprising the enteric nervous system in the intestine of mice.

7 Dec 2020

Genetic variants in pediatric cancer survivors of African ancestry increase risk of heart problems

Scientists at St. Jude Children's Research Hospital recently identified genetic variants in childhood cancer survivors of African ancestry that increase their risk of treatment-related heart problems.

7 Dec 2020

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

A new study indicates that the topoisomerase 1 (Top1) is intimately related to the lethal inflammation associated with SARS-CoV-2 infection in a large proportion of cases.

7 Dec 2020

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

A group of researchers developed a promising fix to CRISPR-Cas9's problem with unwanted genetic changes using a method that allows them to turn off gene-editing until it reaches key cell cycle phases where more accurate repairs are likely to happen.

4 Dec 2020

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

The sugar residues decorating the spike (S) protein of SARS-CoV-2 are essential to the viral-receptor binding.

3 Dec 2020

New insight into role of autophagy in controlling SARS-CoV-2 infection

A team of researchers at the University of Manitoba in Canada said that nanoparticle targeting of autophagy at the sites could be a potent tool to effectively overcome COVID-19 while preventing the common adverse effects of the drug.

2 Dec 2020

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

A team of researchers at the University of Tokyo in Japan have detected a sarbecovirus, called Rc-o319, which is phylogenetically positioned in the same clade as SARS-CoV-2 in Rhinolophus cornutus bats in Japan.

2 Dec 2020

Researchers evaluate the most appropriate test for COVID-19

Until a vaccine is available, curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined.

2 Dec 2020

POSTECH researchers solve the enigma to treating neurological diseases

Neurological diseases of the brain such as dementia, autism and schizophrenia are now a growing social problem. Nevertheless, studies on their definitive cause are still insufficient.

2 Dec 2020

Nanomedicine's giant step into the fight against the COVID-19

A recent editorial in Nature Nanotechnology discusses the enormous feat of scientific innovation, with messenger RNA (mRNA)-based vaccines developed to deliver the gene sequence of specific SARS-CoV-2 viral proteins into host cells using nanotechnology platforms.

1 Dec 2020

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Researchers in Algeria have reviewed some of the evidence suggesting that flavonols commonly found in many plants and vegetables could be used as a therapeutic approach to coronavirus disease 2019 (COVID-19).

1 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Researchers find way for customized programming of human stem cells

Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues for drug testing and cell replacement therapies. However, the "recipes" for this conversion are often complicated and difficult to implement.

30 Nov 2020

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

Many antiviral development studies have focused on the possibility of inhibiting the main viral protease (Mpro), and papain-like protease (PLpro), given their central role in viral replication. A new study draws attention to the high odds that these may not have anti-infective activity because of the redundant pathways present in human host cells.

30 Nov 2020

Transcription News and Research

New 'nanoPCR' technology can accurately diagnose COVID-19 in less than 20 minutes

Study findings can guide personalized breast cancer therapies based on melatonin

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

Single-cell sequencing provides new fundamental insights into 'abdominal brain'

Genetic variants in pediatric cancer survivors of African ancestry increase risk of heart problems

Topoisomerase 1 inhibition prevents SARS-CoV-2-induced inflammation and death in animal models

Researchers develop a promising fix to CRISPR-Cas9's unwanted changes problem

N-Glycosylation sites may contribute to spike-mediated invasion by SARS-CoV-2

New insight into role of autophagy in controlling SARS-CoV-2 infection

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

Researchers evaluate the most appropriate test for COVID-19

POSTECH researchers solve the enigma to treating neurological diseases

Nanomedicine's giant step into the fight against the COVID-19

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

SARS-CoV-2's microRNAs may have promoted its jump to humans

Researchers find way for customized programming of human stem cells

Are SARS-CoV-2 protease inhibitors effective antivirals in treating COVID-19?

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Researchers identify the gene responsible for cellular aging

SARS-CoV-2 launches multipronged attack against host cell protein synthesis, study finds

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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