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Potential cure for heart disease via cancer gene upregulation

Researchers have found that by switching on a gene that promotes the spread of cancers, they can enhance the regeneration of damaged heart muscle. The study results, published in April 2020 in the journal Nature Communication, could mark the beginning of curative therapy for heart disease.

14 Apr 2020

Technologies converge on interacting surfaces in protein complexes

Researchers have fine-tuned a method to pinpoint surfaces within interacting large multi-protein complexes.

14 Apr 2020

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Chinese scientists report high-resolution crystal structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

13 Apr 2020

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

Researchers pinpoint genetic variation responsible for development of IBD

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

9 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020

New Fleischner Society statement on chest imaging and management of COVID-19 published

A multinational consensus statement from the Fleischner Society on the role of chest imaging in the management of patients with COVID-19 was jointly published today in the journals Radiology and Chest.

7 Apr 2020

Thermo Fisher announces availability of AcroMetrix Coronavirus 2019 (COVID-19) RNA Control

Thermo Fisher Scientific, the world leader in serving science, today announced the availability of the Thermo Scientific AcroMetrix Coronavirus 2019 (COVID-19) RNA Control, its latest quality control product to monitor and validate COVID-19 molecular diagnostic tests.

From Thermo Fisher Scientific Inc. 1 Apr 2020

Coronavirus shown to spread in high heat and humidity

A new study explores the possibility that the novel coronavirus, which is ravaging the world, can spread in hot and humid conditions, dispelling the view held by some investigators that the virus is more easily transmissible in colder climates.

30 Mar 2020

Grifols Announces Formal Collaboration with US Government to Produce the First Treatment Specifically Targeting COVID-19

Grifols today announces that it has entered into a formal collaboration with the US Government alongside other health agencies, to treat COVID-19 disease.

From GRIFOLS U.K. Ltd. 27 Mar 2020

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Oncotarget Volume 11, Issue 12 reported that using the HL-60 human non-APL AML model where ATRA causes nuclear enrichment of c-Raf that drives differentiation/G0-arrest, the research team now observe that roscovitine enhanced nuclear enrichment of certain traditionally cytoplasmic signaling molecules and enhanced differentiation and cell cycle arrest.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Coronavirus unlikely to spread through tears

While researchers are certain that coronavirus spreads through mucus and droplets expelled by coughing or sneezing, it is unclear if the virus is spread through other bodily fluids, such as tears.

25 Mar 2020

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Treating T cells harvested from a patient with a combination of an epigenetic drug and a cytokine while expanding the cells in the lab re-programs them into a stronger T cell type that persists longer than its comrades, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Immunology Research, a journal of the American Association for Cancer Research.

25 Mar 2020

Cancer could potentially be treated with new immunotherapy approach, say researchers

Researchers have made a discovery about EGR4 that could instigate a new immunotherapy approach to treating cancer.

25 Mar 2020

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers.

25 Mar 2020

Transcription News and Research

Potential cure for heart disease via cancer gene upregulation

Technologies converge on interacting surfaces in protein complexes

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Chinese scientists report high-resolution crystal structure of COVID-19 main protease

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

Researchers pinpoint genetic variation responsible for development of IBD

Researchers identify protein that plays critical role in cancer treatment-related heart damage

New Fleischner Society statement on chest imaging and management of COVID-19 published

Thermo Fisher announces availability of AcroMetrix Coronavirus 2019 (COVID-19) RNA Control

Coronavirus shown to spread in high heat and humidity

Grifols Announces Formal Collaboration with US Government to Produce the First Treatment Specifically Targeting COVID-19

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Coronavirus unlikely to spread through tears

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Cancer could potentially be treated with new immunotherapy approach, say researchers

YAP signal pathway plays a vital role in the onset of head-and-neck cancer

Study sheds light on myelin's role in 'chemobrain' and multiple sclerosis

A review of the literature on acute promyelocytic leukemia

Researcher working to measure gene expression in blood of patients treated for opioid use disorder

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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