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Chromatrap reports benefits of using ChIP-seq kit for histone methylation applications

Chromatrap reports on the advantages of using its Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits for histone methylation applications.

From Chromatrap® - Porvair Sciences Ltd 16 Sep 2016

New study provides most comprehensive picture to date of head and neck cancer stem cells

Cancer stem cells resist therapy and are a major cause of relapse, long after the bulk of a tumor has been killed.

15 Sep 2016

Research findings may pave way for innovative treatments of multiple sclerosis

Researchers at the Research Center for Immunotherapy and the Focus Program Translational Neurosciences of Johannes Gutenberg University Mainz have identified a new mechanism that is involved in the development of autoimmune diseases.

14 Sep 2016

Researchers identify genes that regulate cellular senescence

A research group including Professor KAMADA Shinji, Research Fellow NAGANO Taiki (both from the Kobe University Biosignal Research Center), and Unit Chief ENARI Masato (National Cancer Research Institute) has succeeded in identifying genes that control cellular senescence - permanently arrested cell growth.

13 Sep 2016

New four-stranded version of DNA may hold key to development of targeted cancer therapies

Scientists have identified where a four-stranded version of DNA exists within the genome of human cells, and suggest that it may hold a key to developing new, targeted therapies for cancer.

13 Sep 2016

Heat shock proteins may play role in triggering Schistosoma invasion

A protein known for helping cells withstand stress may also act as a switch that triggers free-swimming Schistosoma larvae to begin penetrating the skin and transforming into the parasitic flatworms that burden more than 240 million people worldwide with schistosomiasis.

9 Sep 2016

Triptolide molecule can turn into 'cruise missile' against cancer

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant.

9 Sep 2016

MIT biologists unravel lncRNA structure-to-function relationships

Several years ago, biologists discovered a new type of genetic material known as long noncoding RNA. This RNA does not code for proteins and is copied from sections of the genome once believed to be "junk DNA."

9 Sep 2016

Nanopores can be effective way to measure DNA interactions with emerging anti-cancer drugs

Cancer thrives when mutated cells undergo frequent division. Most anti-cancer drugs work by inserting themselves in between the DNA base pairs that encode our genetic information.

1 Sep 2016

Epigenetic changes from stress exposure can be passed from traumatized parent to offspring

The children of traumatized people have long been known to be at increased risk for posttraumatic stress disorder (PTSD), and mood and anxiety disorders.

1 Sep 2016

Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study.

31 Aug 2016

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846.

26 Aug 2016

Protein complex could play key role in natural development of stem cells into healthy blood cells

A group of proteins best known for helping to activate all mammalian genes has been found to play a particularly commanding role in the natural development of specialized stem cells into healthy blood cells, a process known as hematopoiesis.

25 Aug 2016

DNA methylation changes that alter excitability may be involved in neuropsychiatric diseases

Diseases such as epilepsy, neuropathic pain, anxiety, depression, drug addiction and Alzheimer's are all associated with changes in the excitability of brain neurons.

24 Aug 2016

Study may show ways to maintain immunity in older people

A study from Oxford and Basel universities may point the way to maintaining our immune systems as we get older.

22 Aug 2016

Researchers unravel mechanism by which hippocampal stem cells regulate their own fate

To date, it has been assumed that the differentiation of stem cells depends on the environment they are embedded in.

18 Aug 2016

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Scientists at The Scripps Research Institute (TSRI) have taken a big step toward the laboratory re-creation of the “RNA world,” which is generally believed to have preceded modern life forms based on DNA and proteins.

17 Aug 2016

MSU scientists show how special genes stay open to fight against infections

A new discovery at Michigan State University has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections.

17 Aug 2016

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Maintaining appropriate levels of proteins within cells largely relies on a cellular component called the proteasome, which degrades unneeded or defective proteins to recycle the components for the eventual assembly of new proteins.

16 Aug 2016

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Researchers have used CRISPR -- a revolutionary new genetic engineering technique -- to convert cells isolated from mouse connective tissue directly into neuronal cells.

11 Aug 2016

Transcription News and Research

Chromatrap reports benefits of using ChIP-seq kit for histone methylation applications

New study provides most comprehensive picture to date of head and neck cancer stem cells

Research findings may pave way for innovative treatments of multiple sclerosis

Researchers identify genes that regulate cellular senescence

New four-stranded version of DNA may hold key to development of targeted cancer therapies

Heat shock proteins may play role in triggering Schistosoma invasion

Triptolide molecule can turn into 'cruise missile' against cancer

MIT biologists unravel lncRNA structure-to-function relationships

Nanopores can be effective way to measure DNA interactions with emerging anti-cancer drugs

Epigenetic changes from stress exposure can be passed from traumatized parent to offspring

Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Protein complex could play key role in natural development of stem cells into healthy blood cells

DNA methylation changes that alter excitability may be involved in neuropsychiatric diseases

Study may show ways to maintain immunity in older people

Researchers unravel mechanism by which hippocampal stem cells regulate their own fate

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

MSU scientists show how special genes stay open to fight against infections

MGH investigators discover key molecules essential for sensing proteasome dysfunction

Researchers develop new strategy to convert fibroblasts directly into neuronal cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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