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Researchers find crucial signal that switches on eye development

Researchers at the University of Warwick, funded by Wellcome Trust, have uncovered a crucial signal that switches on eye development.

24 Oct 2007

Research shows how stem cells decide to become either skeletal or smooth muscle

Researchers have discovered a key protein that controls how stem cells "choose" to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels, according to a study published in the Proceedings of the National Academy of Sciences (PNAS).

11 Oct 2007

Heat shock proteins are co-opted for cancer

A Jekyll-Hyde mechanism that both protects healthy cells and enables cancer cells could be the basis for new cancer-fighting drugs.

21 Sep 2007

Heat shock proteins are co-opted for cancer

A Jekyll-Hyde mechanism that both protects healthy cells and enables cancer cells could be the basis for new cancer-fighting drugs.

20 Sep 2007

Scientists synthesize DNA-based memory loop in yeast cells

Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology.

17 Sep 2007

Novel mechanism discovered that balances the sizes of functional areas in the brain

In the cerebral cortex, the brain's powerful central processing unit responsible for higher functions, specialized subdivisions known as areas are laid out like a map, but little is known about the genetic forces that shape the geography of our brains.

11 Sep 2007

Research looks at prions and retroviruses

National Research Center for Environment and Health in Neuherberg/Munich (Helmholtz Association of German Research Centres) the group is continuing to search for cellular components whose make-up is changed as a result of a prion infection.

10 Sep 2007

Flies can turn off their immune response

The immune response is actively turned on to target and destroy foreign infectious elements, but in the interests of self-preservation, it is just as important to turn the immune system off to avoid damage to oneself by "friendly fire."

4 Sep 2007

Gene regulation in humans is closer than expected to simple organisms

Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc).

30 Aug 2007

Reactivating a critical gene lost in kidney cancer reduces tumor growth

Researchers at Mayo Clinic Jacksonville, have found that a key gene is often silenced in clear cell renal cell carcinoma, the most common type of kidney cancer, and when they restored that gene in human kidney cancer cells in culture and animal experiments, tumors stopped growing and many disappeared.

17 Aug 2007

Sirtuin protein instrumental in fat production and metabolism

A new Joslin Diabetes Center-led study has identified a protein found in fat cells that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk for type 2 diabetes.

17 Aug 2007

Gene regulation drives evolution

It is not just what's in your genes, it's how you turn them on that accounts for the difference between species , at least in yeast , according to a report by Yale researchers in this week's issue of Science.

11 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007

New gene therapy for 200 inherited forms of blindness

An improved approach to gene therapy may one day treat some of the nearly 200 inherited forms of blindness, scientists at Washington University School of Medicine in St. Louis suggest.

26 Jul 2007

New insights into acute promyelocytic leukemia

Results from two new studies provide key mechanistic insights into the complex molecular events that cause a deadly type of leukemia.

10 Jul 2007

New type of mouse embryonic stem cell discovered

Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem (ES) cells, the National Institutes of Health (NIH) have announced.

28 Jun 2007

Researchers reprogram normal tissue cells into embryonic stem cells

Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.

8 Jun 2007

Researchers turn normal tissue cells into embryonic stem cells

8 Jun 2007

Embryonic stem cells can be created without eggs

Embryonic stem cells are unique because they can develop into virtually any kind of tissue type, an attribute called pluripotency.

8 Jun 2007

Reprogrammed fibroblasts resemble embryonic stem cells

Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline.

8 Jun 2007