Transplant News and Research

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UQ-led clinical trial to test the effectiveness of diabetes drug for polycystic kidney disease

Patient recruitment is underway for a University of Queensland-led clinical trial to test the effectiveness of a diabetes drug to slow the progression of polycystic kidney disease (PKD).

30 Aug 2023

Man-made antibody successfully prevents organ rejection after transplantation

A man-made antibody successfully prevented organ rejection when tested in primates that had undergone a kidney transplant, Duke Health researchers report.

30 Aug 2023

New mechanism of action discovered for pulmonary distress in immunocompromised patients

When an immunocompromised person's system begins to recover and produce more white blood cells, it's usually a good thing – unless they develop a potentially deadly inflammatory condition.

30 Aug 2023

A move to cut drug prices has patients with rare diseases worried

For people with cystic fibrosis, like Sabrina Walker, Trikafta has been a life-changer.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

UC San Francisco scientists develop implantable bioreactor to treat kidney failure

Scientists at UC San Francisco are working on a new approach to treating kidney failure that could one day free people from needing dialysis or having to take harsh drugs to suppress their immune system after a transplant.

29 Aug 2023

Texas Heart Institute receives $2 million NIH grant to develop transplantable bioartificial hearts

The Texas Heart Institute recently received a five-year, $2 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to advance the technology supporting development of transplantable bioartificial hearts.

25 Aug 2023

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

Researchers from the University of Minnesota Medical School and College of Pharmacy have found that high costs for hepatic encephalopathy treatment in patients with end-stage liver disease were associated with decreased treatment retention for patients.

25 Aug 2023

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Alcohol-associated liver disease accounts for 50% of liver-related deaths, and its rates are rising worldwide.

24 Aug 2023

Pioneering drug for rare kidney disease improves outcome for patients

A pioneering drug for a rare kidney disease prevents organ failure and significantly improves the outcome for patients, new research has confirmed.

24 Aug 2023

People with compromised immune systems less likely to have COVID-19 antibodies, study finds

New research has identified which people with compromised immune systems are less likely to have COVID-19 antibodies - making them more vulnerable to a severe infection.

23 Aug 2023

New matching system enables world's first four-way liver exchange

In a breakthrough in liver transplantation that may lead to the ability to connect more living donors and patients, a new matching system designed by a team led by Boston College economists enabled the world's first four-way liver exchange and a cascade of additional matches, researchers reported recently in the American Journal of Transplantation.

22 Aug 2023

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) recently awarded The Texas Heart Institute (THI) a two-year, $1.14 million grant to develop a novel, first-in-class drug to treat cardiovascular disease (CVD) as a significant improvement to current treatment regimens -; specifically for adverse events arising from atherosclerosis.

22 Aug 2023

Doctors advocate fresh efforts to combat Chagas disease, a silent killer

When Maira Gutiérrez was diagnosed with Chagas disease in 1997, neither she nor her primary care physician had even heard of the malady. She discovered her illness only by chance, after participating in a Red Cross blood drive organized by her employer, Universal Studios.

22 Aug 2023

Study finds no link between short-term immunosuppressant use and cancer

Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published today in the journal BMJ Oncology.

21 Aug 2023

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

18 Aug 2023

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

18 Aug 2023

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

Cleveland Clinic London is the first hospital in London to successfully perform a total knee replacement procedure with the assistance of an augmented reality-based surgical platform that was designed with artificial intelligence and machine learning.

18 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Transplant News and Research

UQ-led clinical trial to test the effectiveness of diabetes drug for polycystic kidney disease

Man-made antibody successfully prevents organ rejection after transplantation

New mechanism of action discovered for pulmonary distress in immunocompromised patients

A move to cut drug prices has patients with rare diseases worried

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

UC San Francisco scientists develop implantable bioreactor to treat kidney failure

Texas Heart Institute receives $2 million NIH grant to develop transplantable bioartificial hearts

High cost of hepatic encephalopathy treatment may lead to medication non-adherence

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Pioneering drug for rare kidney disease improves outcome for patients

People with compromised immune systems less likely to have COVID-19 antibodies, study finds

New matching system enables world's first four-way liver exchange

Texas Heart Institute receives $1.14 million grant to develop first-in-class drug to treat cardiovascular disease

Doctors advocate fresh efforts to combat Chagas disease, a silent killer

Study finds no link between short-term immunosuppressant use and cancer

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

A new Medicare proposal would cover training for family caregivers

Pig kidney xenotransplantation continues to function well after 32 days

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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