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Diverse gut microbiome may help children survive stem cell transplant

Researchers in Italy have shown for the first time that among children who have undergone a donor stem cell transplant, the presence of diverse species of micro-organisms in the intestinal tract before the transplant resulted in significantly better overall patient survival and fewer complications.

10 Aug 2023

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

In the ongoing search for a cure for Alzheimer's disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system.

9 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

7 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications.

1 Aug 2023

Three doses of mRNA vaccine provide good protection for vulnerable people

Even vulnerable people, who are at risk of severe Covid-19, achieved good antibody levels after three doses of mRNA vaccine.

1 Aug 2023

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

Study examined the role of plasma metagenomic next-generation sequencing.

1 Aug 2023

New technology could revolutionize treatment for age-related macular degeneration

Scientists have found a way to use nanotechnology to create a 3D 'scaffold' to grow cells from the retina –paving the way for potential new ways of treating a common cause of blindness.

28 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Home sweet parking lot: Some hospitals welcome RV living for patients, families, and workers

Jim Weaver has had two major surgeries in the past decade: one to remove cancerous tumors from his bladder and another to clear a blocked artery.

27 Jul 2023

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

An injectable biomaterial activated by pulses of low-energy blue light has tremendous potential for on-the-spot repair to the domed outer layer of the eye, a team of University of Ottawa researchers and their collaborators have revealed.

26 Jul 2023

Donating a kidney can be safe for people living with HIV, study shows

Based on findings from a study published today in the journal The Lancet Regional Health - Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.

24 Jul 2023

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Study looks at how and where patients with CKD have been excluded from CVD RCTs over the last two decades.

24 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Congress considers easing regulations on air transport of donated organs

What do kidney and pancreas transplants have to do with airplane regulations? Tucked into the hundreds of pages of legislative language to reauthorize the Federal Aviation Administration is a provision to change the life-or-death process by which human organs are flown commercially from donor to recipient.

20 Jul 2023

Proteins CEACAM1 and TIM-3 may help protect liver transplants

A new study identifies how certain proteins in the immune system interact leading to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body's immune response during liver transplantation.

19 Jul 2023

Transplant News and Research

Diverse gut microbiome may help children survive stem cell transplant

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

Understanding variations in SARS-CoV-2 evolution and clearance by immunodeficiency status

UCLA study finds new way to protect livers during transplantation

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Three doses of mRNA vaccine provide good protection for vulnerable people

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

New technology could revolutionize treatment for age-related macular degeneration

New gene editing approach could revolutionize the treatment of blood disorders

Home sweet parking lot: Some hospitals welcome RV living for patients, families, and workers

Biomimetic materials pulsed with low-energy blue light can reshape damaged corneas

Donating a kidney can be safe for people living with HIV, study shows

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Six new Damon Runyon Clinical Investigators announced for 2023

Congress considers easing regulations on air transport of donated organs

Proteins CEACAM1 and TIM-3 may help protect liver transplants

Study sheds light on how viruses override host cell's DNA replication machinery

Normothermic machine preservation shows promise in liver transplantation

Study highlights the potential of cell replacement therapy for Huntington's disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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