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SynCardia Systems submits an IDE application for study of its Freedom discharge driver

On Nov. 5, SynCardia Systems, Inc., manufacturer of the SynCardia temporary CardioWest™ Total Artificial Heart, announced it has submitted an application to the FDA to conduct an Investigational Device Exemption (IDE) clinical study of the Freedom™ discharge driver, designed to power the Total Artificial Heart outside the hospital.

6 Nov 2009

Pfizer extends JAK3 research collaboration with Ligand Pharmaceuticals

Ligand Pharmaceuticals Incorporated announced today that its research collaboration with Pfizer for JAK3 has been extended by one year. The Research and License Agreement entered into in December 2006 with Wyeth provided for an initial three year research term. Under this extension, Ligand will receive $3.1 million in research payments to continue conducting drug discovery and lead candidate optimization.

6 Nov 2009

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Promedior, Inc., a leader in the development of novel therapeutics for the treatment of fibrotic diseases and tissue remodeling, announced today the publication of results from preclinical studies demonstrating that human Serum Amyloid P (hSAP) potently inhibited fibrosis in two independent model systems of kidney fibrosis.

5 Nov 2009

Medivir presents OPERA-1 Phase IIa trial data at the AASLD meeting

Data were presented from the phase IIa trial (OPERA-1) for TMC435 at the ongoing 60th annual meeting of the American Association for the Study of Liver Diseases in Boston, USA.

4 Nov 2009

GI and hepatology societies take initiative to evaluate the current medical school curriculum

Due to the increasing complexities of treating digestive diseases, allowing gastroenterological (GI) trainee physicians the opportunity to develop enhanced abilities and experiences in specific disease areas or procedures will be a great benefit to patients, according to a "Report of the Multisociety Task Force on GI Training."

4 Nov 2009

Comparative study reveals similar brain networks in human and monkey brains

A study published this week in PNAS provides a comprehensive comparative functional anatomy study in human and monkey brains which reveals highly similar brain networks preserved across evolution.

4 Nov 2009

Lung transplant ordeal

After doctors told her that John, her gravely ill husband of 29 years, was too high of a risk for a lung transplant, Ann Lograsso lay next to him in his hospital bed and together the pair wept.

4 Nov 2009

FDA update on BYETTA injection: Amylin Pharmaceuticals and Eli Lilly respond

Amylin Pharmaceuticals, Inc., and Eli Lilly and Company today issued the following statement in response to the U.S. Food and Drug Administration (FDA) update on BYETTA® (exenatide) injection.

3 Nov 2009

Therapy with EBV-specific CTLs effective for severely immune-compromised patients

Specially developed immune system cells that target the common Epstein-Barr virus can protect immune-suppressed bone marrow transplant recipients against lymph system disease and cancers that arise from the viral infection, said a group of researchers led by those from Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital.

3 Nov 2009

Interim data from Bristol-Myers Squibb's BARACLUDE study for chronic hepatitis B patients

Bristol-Myers Squibb today announced 48-week data from an ongoing study (ETV-048) of chronic hepatitis B patients with decompensated cirrhosis, in which BARACLUDE demonstrated greater viral suppression compared to adefovir. The new BARACLUDE data were presented today at the 60th Annual Meeting of the American Association for the Study of Liver Diseases.

2 Nov 2009

Extending hepatitis C treatment for liver transplant patients results in sustained viral clearance

Extending hepatitis C treatment for liver transplant patients beyond current practice results in high rates of clearance of the hepatitis C virus from the blood, as well as a low rate of relapse, according to a Henry Ford Hospital study.

2 Nov 2009

Switching to new immunosuppressant drug may reduce skin cancer after kidney transplantation

Switching to a newer type of immunosuppressant drug may reduce the high rate of skin cancer after kidney transplantation, according to research being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

2 Nov 2009

Lupus patients rarely develop kidney disorders after a kidney transplant

Individuals with a history of lupus who receive a kidney transplant rarely develop the serious inflammatory condition lupus nephritis in their new organ, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

2 Nov 2009

Amgen publishes Phase 3 study results of Aranesp

Amgen today announced the publication of results from TREAT (the Trial to Reduce Cardiovascular Events with Aranesp® Therapy), a large, randomized, double-blind, placebo-controlled, Phase 3 pivotal study of patients with chronic kidney disease (CKD) not on dialysis, moderate anemia and type-2 diabetes.

31 Oct 2009

Dialysis patients at increased risk of infections during travel: Study

If you're sick, traveling to a foreign land may boost your spirits, but jeopardize your health, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA. The findings indicate that dialysis patients who travel on vacation risk infections, anemia, and other complications that can compromise their dialysis treatments.

31 Oct 2009

Race of kidney donors may affect the survival rates of transplant recipients

The race of kidney donors may affect the survival rates of transplant recipients according to a study by Henry Ford Hospital.

31 Oct 2009

Immunotherapy, a new therapeutic area to destroy tumor cells

Targeted immunotherapy has been an attractive new therapeutic area for a number of cancers because it has the potential to destroy tumor cells without damaging surrounding normal tissue. New study results demonstrate high success rates using specialized white blood cells to prevent or treat lymphoma associated with the Epstein-Barr virus (EBV-lymphoma) in patients who have received a hematopoietic stem cell transplant (HSCT).

31 Oct 2009

FDA approves an expanded indication for BYETTA injection

Amylin Pharmaceuticals, Inc., and Eli Lilly and Company (NYSE: LLY) today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded indication for BYETTA® (exenatide) injection. BYETTA is now approved for use as a stand-alone medication (monotherapy) along with diet and exercise to improve glycemic control in adults with type 2 diabetes.

31 Oct 2009

Left side grafting has lower risk to donors; small graft size not the only cause of 'small-for-size graft syndrome'

A recent study by doctors at Shinshu University, School of Medicine, in Japan determined that left side grafting has lower risk to donors compared to grafts taken from the right lobe, and it appears to be the procedure of choice for adult-to-adult living donor liver transplantation (LDLT).

30 Oct 2009

Young medical school graduates more likely to recommend kidney transplantation for CKD patients

Compared with veteran doctors, recent medical school graduates are more likely to refer chronic kidney disease (CKD) patients for kidney transplantation before their patients require dialysis, according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

30 Oct 2009

Transplant News and Research

SynCardia Systems submits an IDE application for study of its Freedom discharge driver

Pfizer extends JAK3 research collaboration with Ligand Pharmaceuticals

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Medivir presents OPERA-1 Phase IIa trial data at the AASLD meeting

GI and hepatology societies take initiative to evaluate the current medical school curriculum

Comparative study reveals similar brain networks in human and monkey brains

Lung transplant ordeal

FDA update on BYETTA injection: Amylin Pharmaceuticals and Eli Lilly respond

Therapy with EBV-specific CTLs effective for severely immune-compromised patients

Interim data from Bristol-Myers Squibb's BARACLUDE study for chronic hepatitis B patients

Extending hepatitis C treatment for liver transplant patients results in sustained viral clearance

Switching to new immunosuppressant drug may reduce skin cancer after kidney transplantation

Lupus patients rarely develop kidney disorders after a kidney transplant

Amgen publishes Phase 3 study results of Aranesp

Dialysis patients at increased risk of infections during travel: Study

Race of kidney donors may affect the survival rates of transplant recipients

Immunotherapy, a new therapeutic area to destroy tumor cells

FDA approves an expanded indication for BYETTA injection

Left side grafting has lower risk to donors; small graft size not the only cause of 'small-for-size graft syndrome'

Young medical school graduates more likely to recommend kidney transplantation for CKD patients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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