Transplant News and Research

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Stem cell funding for Parkinson’s disease

The Parkinson's Disease Society (PD) has announced funding of £170k to the University of Bristol for research into how to make stem cells produce dopamine and live longer after they have been transplanted into animals.

4 Mar 2008

Statistical modeling improves quality of laboratory data

Many areas of research and medicine rely critically upon knowing a person's individual immune system proteins, as they determine an individual's ability to fight disease or mistakenly attack their own tissues.

1 Mar 2008

Cause of effectiveness discovered for a cirrhosis treatment useful in 40 percent of patients

Scientists of the Center for Applied Medical Research (CIMA) of the University of Navarra have discovered the molecular mechanism responsible for the effectiveness of an existing treatment for primary biliary cirrhosis, which combines two substances in order to produce an effect that does not result from either substance separately.

28 Feb 2008

Are cataract rates on the decline?

Should glaucoma patients seeking alternative therapies trust what they find online? Are seatbelts still important to protect eyes in auto accidents, now that most cars have airbags? What's the connection between hearing loss and one form of glaucoma? These are among the topics explored in the March 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

28 Feb 2008

URMC cardiac team celebrates 100th heart transplant

The Program in Heart Failure and Transplantation at the University of Rochester Medical Center has reached a milestone, performing its 100th cardiac transplant surgery.

27 Feb 2008

Researchers engineer first system of human nerve-cell tissue

Researchers at the University of Pennsylvania School of Medicine have demonstrated that living human nerve cells can be engineered into a network that could one day be used for transplants to repair damaged to the nervous system.

27 Feb 2008

Adult-onset obesity seen in mice when gene ubiquitin disrupted

Texas and California scientists who disrupted one type of the gene ubiquitin (Ubb) in mice observed neuronal death in the hypothalamus, impaired control of energy balance and adult-onset obesity in the rodents.

27 Feb 2008

Kidney donor age linked to aortic siffening

Transplantation of kidneys from older donors is followed by increased stiffening of the recipient's aorta - which may help to explain the higher rates of cardiovascular disease and death in patients receiving kidneys from "expanded criteria" donors, reports a study in the April Journal of the American Society of Nephrology.

22 Feb 2008

Protein found in the saliva of deer ticks prevents the HIV-1 virus from attaching to the surface of T cells

The HIV-1 virus cripples the human immune system by targeting white blood cells called T cells that form the body's first line of defense in fighting infections.

17 Feb 2008

Major milestone in the culturing of human blood stem cells

Patients with leukemia, certain autoimmune diseases and genetic defects such as sickle-cell anemia can be treated with blood stem cells either from a donor's bone marrow or from cord blood - but the supply of effective stem cells often runs short.

17 Feb 2008

Researchers use embryonic stem cells to develop functioning immune system blood cells

For the first time, researchers have used embryonic stem cells to develop functioning immune system blood cells -- an important step in eventually using embryonic stem cells as an alternative source of cells for traditional bone marrow transplantations.

14 Feb 2008

New Jefferson trial to test radiation-emitting beads against advanced liver cancer

Liver cancer specialists at Jefferson's Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer.

13 Feb 2008

Discovery that embryonic stem cells can be used to create functional immune system blood cells

A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for bone marrow transplantation.

13 Feb 2008

Researchers study airway bypass procedure for severe emphysema

Researchers at Pulmonary Associates today announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial, an international, multi-center clinical trial to explore an investigational treatment that may offer a new, minimally invasive option for those suffering with advanced widespread emphysema.

12 Feb 2008

Donors' health associated with risk of infection among recipients of corneal transplants

Corneal grafts obtained from donors dying in the hospital or with cancer may be associated with an increased risk of infection for the recipient, according to a report in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

12 Feb 2008

New islet transplantation for patients with Type 1 diabetes

A team led by Dr Richard Smith, Consultant Senior Lecturer in Renal Medicine at North Bristol NHS Trust and the University of Bristol, will offer a pioneering new treatment for some patients with Type 1 diabetes, the Department of Health announced today.

11 Feb 2008

Researchers find new U.S. trend in antibiotic resistance

A research team from The University of Texas Health Science Center at San Antonio, examining bacterial isolates obtained in hospital and non-hospital clinical settings between 2000 and 2006, has identified drug-resistant strains of E. coli and Klebsiella bacteria in more than 50 blood, urine and respiratory samples.

11 Feb 2008