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City of Hope cures oldest person of blood cancer and achieves HIV remission

City of Hope, one of the largest cancer research and treatment organizations in the United States, treated the oldest person to be cured of a blood cancer and then achieve remission for HIV after receiving a blood stem cell transplant from a donor with a rare genetic mutation.

15 Feb 2024

Groundbreaking study sheds light on the potential of the heart to achieve self-repair and regeneration

A groundbreaking scientific study published in Nature Cardiovascular Research has unveiled a remarkable discovery that may have far-reaching implications for the treatment of heart disease.

14 Feb 2024

New guideline aims to improve diagnosis and treatment of cryptococcosis

A group of international mycology experts led by Professor Dr Oliver A. Cornely at the University of Cologne has jointly drafted a guideline for the diagnosis and treatment of cryptococcosis, which aims at improving infection management and thus the survival rate of patients.

13 Feb 2024

Using 3D ice printing to create structures that resemble blood vessels

Over 100,000 individuals in the United States are currently in need of organ transplants. The demand for organs, such as hearts, kidneys, and livers, far exceeds the available supply and people sometimes wait years to receive a donated organ.

12 Feb 2024

GoFundMe has become a health care utility

GoFundMe started as a crowdfunding site for underwriting "ideas and dreams," and, as GoFundMe's co-founders, Andrew Ballester and Brad Damphousse, once put it, "for life's important moments."

12 Feb 2024

Small ultrasound sticker can monitor the stiffness of internal organs

MIT engineers have developed a small ultrasound sticker that can monitor the stiffness of organs deep inside the body.

9 Feb 2024

Stigmatizing language on websites delays care for liver disease patients

The vast majority of liver transplant centers in the United States use language on their websites that can be considered stigmatizing through their use of words like "alcoholism," "alcoholic" and "alcohol abuse,' potentially hindering care and the willingness of patients to seek treatment, a study by Massachusetts General Hospital (MGH) has found.

8 Feb 2024

Ovarian tissue freezing offers hope for extended fertility

Most women agree that menopause has its advantages and disadvantages. Some relish the end of menstruation and concerns about unplanned pregnancies, while others dread the possibililty of hot flashes, moodiness, and other unpleasant symptoms.

6 Feb 2024

NIH awards $1.9 million to investigate how complex communities of microbes impact human health

The bacteria and microorganisms that live within the human body -; the microbiota -; can impact human health, disease risk and even how the body absorbs medications, but the details of these processes are unclear.

5 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

$Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery$

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic.

2 Feb 2024

CRISPR revolutionized: New method edits genes directly in the body

Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient.

1 Feb 2024

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

A recent study co-authored by Dr. Matthew Segar, a third-year cardiovascular disease fellow at The Texas Heart Institute and led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey, utilized a machine learning-based approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF).

31 Jan 2024

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

30 Jan 2024

Study offers insights into who's at risk for long COVID among immunocompromised patients

Early in the pandemic, clinicians noticed that certain immunocompromised patients were experiencing persistent SARS-CoV-2 infections, some lasting weeks to months at a time.

26 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments.

24 Jan 2024

Bladder and gut fermentation syndromes: Uncommon disorders with significant implications

Study reviews bladder fermentation syndrome (BFS) and gut fermentation syndrome (GFS), highlighting their etiology, diagnosis, and treatment, and emphasizing the importance of recognizing these conditions to avoid misinterpretation in abstinence monitoring.

23 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).

23 Jan 2024

Transplant News and Research

City of Hope cures oldest person of blood cancer and achieves HIV remission

Groundbreaking study sheds light on the potential of the heart to achieve self-repair and regeneration

New guideline aims to improve diagnosis and treatment of cryptococcosis

Using 3D ice printing to create structures that resemble blood vessels

GoFundMe has become a health care utility

Small ultrasound sticker can monitor the stiffness of internal organs

Stigmatizing language on websites delays care for liver disease patients

Ovarian tissue freezing offers hope for extended fertility

NIH awards $1.9 million to investigate how complex communities of microbes impact human health

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

CRISPR revolutionized: New method edits genes directly in the body

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

Study offers insights into who's at risk for long COVID among immunocompromised patients

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Bladder and gut fermentation syndromes: Uncommon disorders with significant implications

3D-printed liver model paves way for new MASH treatments

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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