Tularemia is a disease of animals and humans caused by the bacterium Francisella tularensis. Rabbits, hares, and rodents are especially susceptible and often die in large numbers during outbreaks. Humans can become infected through several routes, including tick and deer fly bites, skin contact with infected animals, ingestion of contaminated water, or inhalation of contaminated dusts or aerosols. In addition, humans could be exposed as a result of bioterrorism. Symptoms vary depending upon the route of infection. Although tularemia can be life-threatening, most infections can be treated successfully with antibiotics. Steps to prevent tularemia include use of insect repellent, wearing gloves when handling sick or dead animals, and not mowing over dead animals. In the United States, naturally occurring infections have been reported from all States except Hawaii.
In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.
A new study has been launched in Burkina Faso for Bharat Biotech's typhoid conjugate vaccine. It is the second clinical study underway in Africa for the vaccine and the first in West Africa.
In Germany, 41 cases of tularemia were reported in 2016. The infections are mainly due to direct contact with infected animals or with insect vectors like ticks and mosquitos.
National Institutes of Health researchers have identified a naturally occurring lipid--a waxy, fatty acid--used by a disease-causing bacterium to impair the host immune response and increase the chance of infection. Inadvertently, they also may have found a potent inflammation therapy against bacterial and viral diseases.
Scientists from the National Institute of Allergy and Infectious Diseases--part of the National Institutes of Health--have unraveled the process by which the bacteria cause disease.
The Centers for Disease Control and Prevention (CDC) has released a new report warning people about the myriad of diseases that are transmitted via bites of blood-sucking insects such as ticks, mosquitoes and fleas calling it a “growing health problem” in the United States.
Today the University of Maryland School of Medicine's Center for Vaccine Development is proud to be part of vaccine history in Africa.
Tularemia is an infectious bacterial disease that is life-threatening for rodents, rabbits and hares, but which can also infect humans and dogs.
During World War II, the Soviet Red Army was forced to move their biological warfare operations out of the path of advancing Nazi troops. Among the dangerous cargo were vials of Francisella tularensis, the organism that causes tularemia and one of the world's most infectious pathogens.
Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.
Everyone agrees that ticks are exceedingly nasty creatures. For hundreds of millions of years, they have survived on Earth by sucking blood from their victims for days, often leaving behind terrible diseases as a thank-you note.
The virulent pathogen that causes the disease tularemia, or "rabbit fever," was weaponized during past world wars and is considered a potential bioweapon.
Researchers in the College of Veterinary Medicine at Kansas State University have validated a model showing growth in Kansas for the habitat of the troublesome lone star tick.
Bacteria have evolved thousands of clever tactics for invading our bodies while evading our natural defenses. Now, UNC School of Medicine scientists studying one of the world's most virulent pathogens and a separate very common bacterium have discovered a new way that some bacteria can spread rapidly throughout the body - by hitchhiking on our own immune cells.
Saint Louis University's Vaccine and Treatment Evaluation Unit has received a five-year, $5.8 million contract from the National Institutes of Health to support an "omics" research initiative to study the safety and effectiveness of vaccines and other ways to fight infectious diseases.
A mild disease spread by the aggressive Lone star tick that is now colonizing large swaths of the United States is being mistaken for Rocky Mountain spotted fever, according to a new study from scientists at the U.S. Centers for Disease Control and Prevention.
Recent outbreaks of plague, tularemia and increasing incidents of rabies exposure highlight the importance of zoonotic disease education for physicians and public health professionals.
The Entomological Society of America (ESA) recently released a statement supporting the creation and implementation of a national strategy using Integrated Tick Management to better control tick populations and reduce the rapidly escalating impact of tick-borne diseases such as Rocky Mountain spotted fever, tularemia, and Lyme disease.
Tick-borne diseases are a major public health problem around the world. Ticks carry and transmit a variety of microbes that cause disease. These illnesses, which include Lyme disease, Rocky Mountain spotted fever, and Tularemia, can cause a variety of symptoms, often serious and sometimes deadly.
Research led by scientists at St. Jude Children's Research Hospital has identified key molecules that trigger the immune system to launch an attack on the bacterium that causes tularemia.