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Even small-stage oral SCC metastases impact prognosis

The presence of even small tumor-cell deposits in the lymph nodes of patients with early oral and oropharyngeal squamous cell carcinoma reflects a potential for the primary tumor to metastasize, report researchers in Head and Neck.

21 Jun 2012

FOXO3a transcription factor actually promotes growth of anaplastic thyroid cancer

A molecule widely believed to fight many forms of cancer actually helps deadly thyroid tumors grow, and cancer therapies now being tested in humans might boost the activity of this newly revealed bad guy, researchers at Mayo Clinic in Florida say.

21 Jun 2012

GBM patients with CNP subtype may have less aggressive subtype of cancer

A diagnosis of glioblastoma multiforme (GBM) is generally a death sentence, but new research from the University of Wisconsin-Madison lab of Dr. John Kuo shows that at least one subtype is associated with a longer life expectancy. This discovery could help with better patient prognoses and lead to targeted drug treatments for GBM subtypes.

21 Jun 2012

New robotic device can improve detection of breast cancer

One in eight women in the United States will develop breast cancer over the course of her lifetime. Lorraine G. Olson, professor of mechanical engineering at the Rose-Hulman Institute of Technology in Terre Haute, Indiana, was diagnosed in 2005 at the age of 45. Fortunately, her breast cancer was caught early from a routine mammogram, but like many women, she was prodded by her physician to do the exam.

21 Jun 2012

Omega-3 fatty acid supplements can reduce inflammation in overweight older adults

New research shows that omega-3 fatty acid supplements can lower inflammation in healthy, but overweight, middle-aged and older adults, suggesting that regular use of these supplements could help protect against and treat certain illnesses.

21 Jun 2012

Value of pathology review highlighted in node-negative breast cancer

Secondary pathology review results in significant changes in diagnosis and treatment for women with node-negative breast cancer, Canadian researchers report.

20 Jun 2012

Researchers determine structure of MRN complex

Double-stranded breaks in cellular DNA can trigger tumorigenesis. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have now determined the structure of a protein involved in the repair and signaling of DNA double-strand breaks. The work throws new light on the origins of neurodegenerative diseases and certain tumor types.

20 Jun 2012

Combination therapy may help defeat pancreatic cancer

Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held here June 18-21.

20 Jun 2012

KPT-SINEs might offer new treatment for people with acute leukemia

A novel family of experimental agents that blocks a molecule from shuttling proteins out of the cell nucleus might offer a new treatment for people with acute leukemia, according to a study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

20 Jun 2012

Commensal bacteria essential to fight off viral infections

Healthy humans harbor an enormous and diverse group of bacteria and other bugs that live within their intestines. These microbial partners provide beneficial aid in multiple ways - from helping digest food to the development of a healthy immune system.

19 Jun 2012

FORMA, TD2 leverage synergistic capabilities to jointly develop transformative cancer therapies

FORMA Therapeutics and TGen Drug Development (TD2) today announced an agreement to jointly develop transformative cancer therapies, leveraging the synergistic capabilities of both organizations.

19 Jun 2012

Study on identification of novel stem cell population in neuroblastoma to be presented at ANR conference

Dr. Eugene Kim, a pediatric surgeon with Texas Children's Cancer Center and assistant professor of surgery at Baylor College of Medicine (BCM), and Dr. Jason Shohet, chair of the Neuroblastoma Research Program at Texas Children's Cancer Center and associate professor in the Section of Hematology-Oncology at BCM, will speak at the Advances in Neuroblastoma Research (ANR) conference about the identification of a novel stem cell population in neuroblastoma.

19 Jun 2012

Multi-institutional research uncovers new mechanism for treatment of lung cancer

A multi-institutional research study has uncovered a new mechanism that may lead to unique treatments for lung cancer, one of the leading causes of death worldwide.

18 Jun 2012

BEAMing DNA blood testing technology detects drug resistance in colorectal cancer patients early

Two studies published back-to-back in last week's Nature applied DNA blood testing using the BEAMing technology to detect drug resistance mediated by KRAS mutations in colorectal cancer patients months before treatment failure was observed.

18 Jun 2012

Cancer publishes Aeterna Zentaris' perifosine Phase 2 trials in RCC

Aeterna Zentaris Inc. today announced that data from two Phase 2 trials in renal cell carcinoma (RCC) for the Company's oral anticancer drug, perifosine, have been published in the June 2012 issue of Cancer, a publication of the American Cancer Society.

18 Jun 2012

Agility MLC's new design provides better dose sculpting capabilities

Requiring only a quick upgrade to their existing Elekta Synergy linear accelerator, physicians at SALK and Paracelsus Medical University began using the new Agility 160-leaf multileaf collimator (MLC), treating 33 patients on its first day. In its first month of Agility use, the center now treats 50 patients per day, comprising about 700 individual treatment sessions that have benefited from this breakthrough in cancer care.

From Elekta 18 Jun 2012

Ascepion, Debiopharm partner to develop and commercialize ASP-08126 for solid tumors

Debiopharm Group, a global biopharmaceutical development specialist that focuses on serious medical conditions and particularly oncology, and Ascepion Pharmaceuticals, Inc., a privately-held, biopharmaceutical company dedicated to the discovery and development of breakthrough small molecule drugs for the treatment of oncology and related diseases, have entered into an exclusive worldwide license agreement concerning the development and commercialization of ASP-08126 (called Debio 1144 by Debiopharm) a multikinase inhibitor currently in pre-clinical development.

18 Jun 2012

NHS Supply Chain signs deal to purchase 10 Elekta Synergy radiation therapy treatment systems

NHS Supply Chain will bring state-of-the-art cancer treatment to the United Kingdom by signing a deal to purchase ten Elekta Synergy radiation therapy treatment systems.

From Elekta 18 Jun 2012

Surprising effects of brain injury

When Maria Ross' husband found his healthy and active wife unconscious on the bathroom floor, the pair had no idea they would embark on a journey into the world of brain injury, learning more about how trauma affects the brain - and your identity - than they ever cared to know.

16 Jun 2012

New approach to drug design may yield more effective and less toxic cancer medicines

A new approach to drug design, pioneered by a group of researchers at the University of California, San Francisco (UCSF) and Mt. Sinai, New York, promises to help identify future drugs to fight cancer and other diseases that will be more effective and have fewer side effects.

16 Jun 2012

Tumor News and Research

Even small-stage oral SCC metastases impact prognosis

FOXO3a transcription factor actually promotes growth of anaplastic thyroid cancer

GBM patients with CNP subtype may have less aggressive subtype of cancer

New robotic device can improve detection of breast cancer

Omega-3 fatty acid supplements can reduce inflammation in overweight older adults

Value of pathology review highlighted in node-negative breast cancer

Researchers determine structure of MRN complex

Combination therapy may help defeat pancreatic cancer

KPT-SINEs might offer new treatment for people with acute leukemia

Commensal bacteria essential to fight off viral infections

FORMA, TD2 leverage synergistic capabilities to jointly develop transformative cancer therapies

Study on identification of novel stem cell population in neuroblastoma to be presented at ANR conference

Multi-institutional research uncovers new mechanism for treatment of lung cancer

BEAMing DNA blood testing technology detects drug resistance in colorectal cancer patients early

Cancer publishes Aeterna Zentaris' perifosine Phase 2 trials in RCC

Agility MLC's new design provides better dose sculpting capabilities

Ascepion, Debiopharm partner to develop and commercialize ASP-08126 for solid tumors

NHS Supply Chain signs deal to purchase 10 Elekta Synergy radiation therapy treatment systems

Surprising effects of brain injury

New approach to drug design may yield more effective and less toxic cancer medicines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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