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OncoSec to purchase $7.75M of securities in registered public offering

OncoSec Medical Incorporated, which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumor cancers, announced today that it has entered into definitive agreements with institutional investors to purchase $7.75 million of securities in a registered public offering.

26 Mar 2012

Enrollment complete in Clovis' CO-101 pivotal study for metastatic pancreatic cancer

Clovis Oncology, Inc. announced today that it has reached the target enrollment in its pivotal LEAP (Low hENT1 and Adenocarcinoma of the Pancreas) study of CO-101 in metastatic pancreatic cancer.

26 Mar 2012

National Colon Cancer Awareness Month attempts to widen screening efforts

March is the National Colon Cancer Awareness Month and to mark it Ferrell Hospital and Harrisburg Medical Center have teamed up with the American Cancer Society to provide free take-home colon cancer tests to anyone who is interested.

25 Mar 2012

Genetic marker identifies tumors unable to repair DNA damage by platinum agents

Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will likely respond to platinum-based chemotherapies.

23 Mar 2012

Treatment with aromatase inhibitors enables some women to have lumpectomy

Preoperative treatment with aromatase inhibitors increases the likelihood that postmenopausal women with estrogen receptor-positive breast cancer will be able to have breast-conserving surgery rather than a mastectomy, according to the results of a national clinical trial presented today at the Society of Surgical Oncology annual meeting in Orlando, Fla.

23 Mar 2012

OncoSec to present data from head and neck cancer studies at two upcoming conferences

OncoSec Medical Incorporated., which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumor cancers, today announced that the company has been selected to present data from its Phase III and IV head and neck cancer studies at two upcoming conferences.

23 Mar 2012

Boston Scientific's WallFlex Stent technology now available for interventional radiologists

Boston Scientific Corporation announces the U.S. and international launch of the WallFlex Biliary Transhepatic Stent System.

23 Mar 2012

Scientists artificially derive brain stem cells from connective tissue of mice

These stem cells can reproduce and be converted into various types of brain cells. To date, only reprogramming in brain cells that were already fully developed or which had only a limited ability to divide was possible. The new reprogramming method presented by the Bonn scientists and submitted for publication in July 2011 now enables derivation of brain stem cells that are still immature and able to undergo practically unlimited division to be extracted from conventional body cells.

23 Mar 2012

PFKFB4 gene leads to excessive growth of prostate cancer cells

Cancer cell metabolism may present a new target for therapy as scientists have uncovered a possible gene that leads to greater growth of prostate cancer cells.

23 Mar 2012

WCI technique uses MRS to detect oncometabolites

Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite", a chemical produced by some brain tumors' warped metabolism, via non-invasive imaging.

23 Mar 2012

Study demonstrates molecular mechanisms of cadmium-induced prostate cancer

A recent study conducted at Marshall University may eventually help scientists develop new treatments for prostate cancer, the most common malignancy in American men.

22 Mar 2012

Opioids may influence breast cancer survival

A new study in the April issue of Anesthesiology analyzed inherited (genetic) differences in how the body responds to its own morphine-like chemicals and pain-relieving opioid drugs, and whether they influence breast cancer survival. Preclinical animal studies have suggested that opioids may promote tumor growth.

22 Mar 2012

AACR to honor PU professor with Award for Outstanding Achievement in Cancer Research

A researcher from The Cancer Institute of New Jersey (CINJ) and Princeton University who is helping to advance the molecular understanding of cancer metastasis is being recognized for his work by cancer specialists from around the globe.

22 Mar 2012

Researchers explain how obscurins suppress breast cancer formation

A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast.

22 Mar 2012

Scientists create worm model of back-up telomere repair strategy

Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome.

22 Mar 2012

Thromboembolic events can occur after musculoskeletal injury and related surgery

Below is a news summary of an orthopaedic research study appearing in the March 21, 2012 issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issues' full Table of Contents.

22 Mar 2012

CBSM intervention can alter tumor-promoting processes in women with breast cancer

A team of researchers led by Michael H. Antoni, director of the Center for Psycho-Oncology Research at the University of Miami (UM) has shown that a stress management program tailored to women with breast cancer can alter tumor-promoting processes at the molecular level. The new study recently published in the journal Biological Psychiatry is one of the first to link psychological intervention with genetic expression in cancer patients.

22 Mar 2012

Advances in Neuroimmune Biology explores maternal-fetal interactions

Fertility problems, recurrent miscarriages, and pregnancy complications can occur when maternal immunological tolerance of the fetus is impaired. G-rard Chaouat and colleagues from Inserm et Assistance Publique et Universit- Paris Sud Orsay, Hopital Antoine B-cl-re, Clamart Cedex, France, trace the evolution of the science of reproductive immunology to show how the current understanding of maternal-fetal tolerance/dialogue has developed, and its implications for the treatment of infertility disorders

22 Mar 2012

Study finds higher death rate in calorie-restricted models of IBD

In a surprising result, Michigan State University researchers looking at the effects of diet on bowel disease found that mice on a calorie-restricted diet were more likely to die after being infected with an inflammation-causing bacterial pathogen in the colon.

21 Mar 2012

Fat-enclosed nanoparticles can directly irradiate brain tumor

For the past 40 years, radiation has been the most effective method for treating deadly brain tumors called glioblastomas. But, although the targeting technology has been refined, beams of radiation still must pass through healthy brain tissue to reach the tumor, and patients can only tolerate small amounts before developing serious side effects.

21 Mar 2012