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Intravenous Phenoxodiol-cisplatin combination well tolerated in platinum resistant ovarian cancer

Marshall Edwards, Inc., an oncology company focused on the clinical development of novel therapeutics targeting cancer metabolism, announced today the publication of results from a Phase II clinical trial of intravenous Phenoxodiol in combination with cisplatin in women with platinum-resistant ovarian cancer.

21 Mar 2011

Organic, non-toxic, biodegradable nanoparticle uses light and heat to treat cancer

A team of scientists from Princess Margaret Hospital have created an organic nanoparticle that is completely non-toxic, biodegradable and nimble in the way it uses light and heat to treat cancer and deliver drugs.

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

ACRIN, ECOG, NCI intent to merge their clinical cancer research programs

The American College of Radiology's Imaging Network and the Eastern Cooperative Oncology Group, National Cancer Institute Clinical Trials Cooperative Group members, today announced their intent to merge their clinical cancer research programs.

19 Mar 2011

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Polaris Group announced today the enrollment of the first patient in a Phase 2 clinical trial of ADI-PEG 20, the company's novel enzyme-based treatment for malignant mesothelioma.

19 Mar 2011

Cancer Care Partners first in U.S. to use new, advanced cancer treatment

On March 7, 2010, Cancer Care Partners became the first cancer center in the United States to use the new TomotherapyHD, a comprehensive, image guided radiation therapy system that enables Cancer Care Partners to more efficiently treat complex tumors with improved precision.

18 Mar 2011

GHDX presents Oncotype DX breast cancer test study results at St. Gallen conference

Genomic Health, Inc. today announced results from nine studies utilizing the Oncotype DX test in early-stage breast cancer patients at the 12th Annual St. Gallen International Breast Cancer Conference in St. Gallen, Switzerland.

18 Mar 2011

FDA advisory panel votes in favor of NovoTTF-100A System for supra-tentorial glioblastoma multiforme tumors

Novocure announced today that the U.S. Food and Drug Administration (FDA) Neurological Devices Advisory Panel of the Medical Devices Advisory Committee voted (7 yes; 3 no; 2 abstain) that for patients with supra-tentorial glioblastoma multiforme (GBM) tumors that recur after maximal surgical and radiation treatments, there is reasonable assurance that the benefits of the NovoTTF-100A System (NovoTTF) outweigh its risks when administered as a monotherapy in place of standard medical therapy.

18 Mar 2011

Individualized dentritic cell vaccine may increase survival time in patients with glioblastoma

A dendritic cell vaccine personalized for each individual based on the patient's own tumor may increase median survival time in those with a deadly form of brain cancer called glioblastoma, an early phase study at UCLA's Jonsson Comprehensive Cancer Center has found.

18 Mar 2011

BUSM scientists identify new biomarker and melanoma treatment target

Researchers at Boston University School of Medicine, in collaboration with Johns Hopkins University, have identified a potential new biomarker and therapeutic target for melanoma.

18 Mar 2011

CytRx commences INNO-206 Phase 1b trial in advanced solid tumors

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced that it has initiated an open-label Phase 1b safety and dose escalation clinical trial with INNO-206 at the Sarcoma Oncology Center in Santa Monica, California. The clinical trial will include up to 24 patients with advanced solid tumors who have failed standard therapies.

17 Mar 2011

Inovio signs agreement with OncoSec to sell non-DNA cancer vaccine technology

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that it has signed an agreement with OncoSec Medical Inc. providing for the sale to OncoSec of certain non-DNA vaccine technology and intellectual property relating to electroporation technology useful for electrochemical and cytokine based immune therapies for treating solid tumors.

17 Mar 2011

Researchers update 'Hallmarks of Cancer' seminal review

Renowned cancer researchers Robert Weinberg, a Founding Member of Whitehead Institute, and Douglas Hanahan, Director of the Swiss Institute for Experimental Cancer Research have updated their seminal review, "Hallmarks of Cancer," which has influenced the study of cancer and the development of therapeutics for more than a decade.

17 Mar 2011

Leading cancer center to acquire GammaMed brachytherapy from Varian

Cancer patients in China will gain access to Varian's state-of-the-art cancer care with the announcement that a leading cancer center is acquiring a GammaMed brachytherapy afterloader from Varian Medical Systems.

17 Mar 2011

HGSI, FivePrime enter agreement to develop, commercialize FP-1039 for multiple cancers

Human Genome Sciences, Inc. and FivePrime Therapeutics, Inc. announced today that they have entered into an agreement to develop and commercialize FivePrime's FP-1039 product for multiple cancers.

17 Mar 2011

Personalized dendritic cell vaccine may increase median survival in mesenchymal glioblastoma patients

17 Mar 2011

Scientists create new drug delivery system to treat cancer

Scientists in Syracuse University's Chemistry Department have created a new drug delivery system expected to advance the effectiveness of cancer-killing drugs. It uses gold nanoparticles with attached DNA that binds to a proven anti-cancer drug, Doxorubicin or DOX.

16 Mar 2011

Researcher argues against use of Cop1-inhibitory drugs for cancer treatment

Jean-Christophe Marine strongly argues against the use of Cop1-inhibitory drugs. The protein Cop1 has -for a long time - been seen as an attractive drug target for cancer. But Jean-Christophe Marine found out that Cop1 acts as a tumor suppressor, and thus inhibits tumor formation. His new data will have direct implications for the development of cancer drug targets.

16 Mar 2011

Malaria drug shrinks, slows resistant pancreatic tumors

Dana-Farber Cancer Institute scientists report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis.

16 Mar 2011

BRAF gene defect leads to pilocytic astrocytoma in children

Pilocytic astrocytoma, the most common brain tumor in children, is usually slow-growing and benign. However, surgeons often cannot completely remove the diffusely growing tumor.

16 Mar 2011

Tumor News and Research

Intravenous Phenoxodiol-cisplatin combination well tolerated in platinum resistant ovarian cancer

Organic, non-toxic, biodegradable nanoparticle uses light and heat to treat cancer

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

ACRIN, ECOG, NCI intent to merge their clinical cancer research programs

Polaris initiates ADI-PEG 20 Phase 2 trial in patients with malignant mesothelioma

Cancer Care Partners first in U.S. to use new, advanced cancer treatment

GHDX presents Oncotype DX breast cancer test study results at St. Gallen conference

FDA advisory panel votes in favor of NovoTTF-100A System for supra-tentorial glioblastoma multiforme tumors

Individualized dentritic cell vaccine may increase survival time in patients with glioblastoma

BUSM scientists identify new biomarker and melanoma treatment target

CytRx commences INNO-206 Phase 1b trial in advanced solid tumors

Inovio signs agreement with OncoSec to sell non-DNA cancer vaccine technology

Researchers update 'Hallmarks of Cancer' seminal review

Leading cancer center to acquire GammaMed brachytherapy from Varian

HGSI, FivePrime enter agreement to develop, commercialize FP-1039 for multiple cancers

Personalized dendritic cell vaccine may increase median survival in mesenchymal glioblastoma patients

Scientists create new drug delivery system to treat cancer

Researcher argues against use of Cop1-inhibitory drugs for cancer treatment

Malaria drug shrinks, slows resistant pancreatic tumors

BRAF gene defect leads to pilocytic astrocytoma in children

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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