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Cerasome filled molecular-sized bubbles to target liver cancer cells

Nanotechnology may open a new door on the treatment of liver cancer, according to a team of Penn State College of Medicine researchers. They used molecular-sized bubbles filled with chemotherapy drugs to prevent cell growth and initiate cell death in test tubes and mice.

23 Feb 2011

American Journal of Clinical Oncology publishes CTI's OPAXIO phase II results against esophageal cancer

Cell Therapeutics, Inc. announced today that updated phase II study results of OPAXIO in patients with advanced esophageal cancer conducted by the Brown University Oncology Group were published in the February 3, 2011 issue of the American Journal of Clinical Oncology, Dipetrillo, et al., which demonstrate that 38% of the patients receiving OPAXIO in combination with cisplatin and concurrent radiation achieved a pathologic or endoscopic complete response.

23 Feb 2011

Mechanism of cancer treatment related to infertility in women

Chemotherapeutic agents, used in cancer treatment, destroy not only cancer cells but also healthy cells, thus affecting germ cells as well. Consequently, after surviving cancer many female patients are confronted with the diagnosis: infertility. For a long time a relationship between infertility and chemotherapeutic agents has been assumed, but until now, the exact mechanism was not known.

23 Feb 2011

Researchers discover biological pathway that alters normal cells into aggressive tumors

A biological pathway that transforms normal cells into aggressive tumors has been discovered by researchers at Cleveland Clinic's Lerner Research Institute.

23 Feb 2011

Research: Drug developed for controlling cholesterol synthesis can kill human breast cancer cells

A University of Missouri researcher believes there could be a new drug compound that could kill breast cancer cells. The compound might also help with controlling cholesterol.

23 Feb 2011

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced the initiation of the randomized Phase 2 portion of the trial of IPI-926 in combination with gemcitabine in patients with previously untreated, metastatic, pancreatic cancer.

22 Feb 2011

First robotically-assisted liver resection performed at Jefferson University Hospital

Cataldo Doria, M.D., Ph.D., Nicoletti Family Professor of Transplant Surgery at Jefferson Medical College of Thomas Jefferson University; director of the Division of Transplantation; and co-director of the liver tumor program at Thomas Jefferson University Hospital is the first surgeon at Jefferson to perform a robotically-assisted liver resection. He is only one of a handful of surgeons across the country certified to do so.

22 Feb 2011

Studies identify protein that drives inflammation in pancreatic, breast tumors

Separate studies published online on February 21 in the Journal of Experimental Medicine (www.jem.org) identify a protein that drives tumor-promoting inflammation in pancreatic and breast tumors.

21 Feb 2011

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

ADVANCELL, an emerging biopharmaceutical company, today announced positive results from a clinical study conducted with Acadra (Acadesine) in Chronic Lymphocytic Leukemia patients resistant to current therapies. The company also announced promising non-clinical results in Multiple Myeloma (MM), Mantle Cell Lymphoma (MCL) and other lymphoproliferative disorders. Synergism of Acadra in combination with current treatment in these indications has been demonstrated.

21 Feb 2011

ESMO creates new Community Oncology Working Group to ensure best standards of care

Receiving a cancer diagnosis is a devastating experience. Still under the shock of the bad news, patients must make many choices including who to turn to for advice and treatment, with the possibility to choose among a comprehensive cancer center, a university hospital or a community oncology hospital.

21 Feb 2011

Researchers receive $2 million NIH grant to identify biomarkers in children with hemangiomas

A nearly $2 million grant from the National Institutes of Health will help investigators at Nationwide Children's Hospital search for biomarkers that may be linked to the development and outcome of hemangiomas, the most common soft tissue tumor in children.

21 Feb 2011

John Theurer chief to present videos on new limb-sparing surgical techniques at AAOS conference

James C. Wittig, M.D., chief of the division of skin and sarcoma cancer at the John Theurer Cancer Center at Hackensack University Medical Center will present eleven different educational videos on innovative approaches to orthopedic oncology at the upcoming American Academy of Orthopaedic Surgeons Conference.

20 Feb 2011

Professor develops optical technology that can detect, examine skin lesions

University of Rochester optics professor Jannick Rolland has developed an optical technology that provides unprecedented images under the skin's surface.

20 Feb 2011

Gene that causes rare breast cancer identified

Researchers have found that a rare but hard-to-treat form of breast cancer is driven by a newly discovered gene. The gene ZNF703 is the first oncogene to be discovered in five years, and it could lead to more effective treatments down the road, Cancer Research UK said.

20 Feb 2011

Phase I/II safety, efficacy data for Bellicum's BPX-101 presented at 2011 Genitourinary Cancers Symposium

Bellicum Pharmaceuticals, Inc. today announced the presentation of Phase I/II safety and efficacy data for BPX-101, a novel drug-activated dendritic cell vaccine for metastatic castrate resistant prostate cancer (mCRPC), in three separate posters at the 2011 Genitourinary Cancers Symposium held in Orlando, Florida on February 17 – 19, 2011.

19 Feb 2011

NY neurosurgeon performs deep brain surgeries with hand-held CO2 laser

Lee Eric Tessler, MD, a neurosurgeon specializing in the treatment of brain tumors, is among the first in metro New York to use a new advanced, hand-held CO2 (carbon dioxide) laser for surgeries on certain types of tumors that are buried deep within the base of the skull. The laser allows surgeons to remove these difficult-to-reach tumors in less time, with lower risk of complications, less anesthesia and a smaller possibility of damage to surrounding healthy brain and nerve tissue.

19 Feb 2011

Biocare, HJF sign license agreement to distribute antibody against prostate cancer

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. has signed a licensing agreement with Biocare Medical, a biotechnology company based in Concord, Calif., for the exclusive worldwide sales and distribution rights for the immunohistochemistry of an antibody designed to detect tumor prevalence in prostate cancer patients.

18 Feb 2011

Medical expert speaks about effects of sugar on human body

With the many forms of sugar available, from table sugar, to high-fructose corn syrup to agave and honey, understanding the differences between sugars and their effects on the body is not all sweet.

18 Feb 2011

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Cyclacel Pharmaceuticals, Inc., today announced the publication of preclinical data in the Proceedings of the National Academy of Sciences (PNAS), demonstrating that cyclin E plays a major role in making Human Epidermal growth factor Receptor 2 positive (HER2+) breast cancer resistant to trastuzumab (Herceptin®), a widely used medicine for breast cancer patients who test positive for HER2.

18 Feb 2011

Positive interim data from cabozantinib Phase 2 metastatic castration-resistant prostate cancer trial

Exelixis, Inc. today reported updated interim data from the cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with cabozantinib (XL184) in an ongoing phase 2 adaptive randomized discontinuation trial.

18 Feb 2011

Tumor News and Research

Cerasome filled molecular-sized bubbles to target liver cancer cells

American Journal of Clinical Oncology publishes CTI's OPAXIO phase II results against esophageal cancer

Mechanism of cancer treatment related to infertility in women

Researchers discover biological pathway that alters normal cells into aggressive tumors

Research: Drug developed for controlling cholesterol synthesis can kill human breast cancer cells

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

First robotically-assisted liver resection performed at Jefferson University Hospital

Studies identify protein that drives inflammation in pancreatic, breast tumors

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

ESMO creates new Community Oncology Working Group to ensure best standards of care

Researchers receive $2 million NIH grant to identify biomarkers in children with hemangiomas

John Theurer chief to present videos on new limb-sparing surgical techniques at AAOS conference

Professor develops optical technology that can detect, examine skin lesions

Gene that causes rare breast cancer identified

Phase I/II safety, efficacy data for Bellicum's BPX-101 presented at 2011 Genitourinary Cancers Symposium

NY neurosurgeon performs deep brain surgeries with hand-held CO2 laser

Biocare, HJF sign license agreement to distribute antibody against prostate cancer

Medical expert speaks about effects of sugar on human body

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Positive interim data from cabozantinib Phase 2 metastatic castration-resistant prostate cancer trial

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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